En Huang
Associate Professor
Also affiliated: Wuhan Polytechnic University (2018); Brown University (2005); Ghent University (2021); The Ohio State University (2012–2024); Temple University (2022)
Faculty Researcher
Environmental Health Sciences, College of Public Health
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
En Huang researches the development of natural antimicrobial compounds to enhance food safety and quality. This work includes discovering and characterizing natural antimicrobial peptides, such as bacteriocins, and lipopeptides using chemical and genetic methods. These agents have potential applications as natural food preservatives, animal feed additives, or novel antibiotics against drug-resistant bacteria.
Huang also investigates the transmission, ecology, and evolution of foodborne pathogens and spoilage microorganisms. This research utilizes genomic, transcriptomic, and metagenomic approaches. Huang's work on cefiderocol resistance in carbapenem-resistant pathogens has been supported by a $1 grant from the NIH/National Institute of Allergy and Infectious Diseases, with Huang serving as PI.
With a career h-index of 18 and 957 citations across 48 publications, Huang actively collaborates with researchers at the University of Arkansas for Medical Sciences, including Sun Hee Moon (7 shared publications) and Se‐Ran Jun (5 shared publications). Huang maintains an active lab website and is a recently active researcher.
Metrics
- h-index: 18
- Publications: 48
- Citations: 970
Selected Publications
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Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce (2024)
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Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i> (2024)
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A Multidrug-Resistant Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacter hormaechei Strain from Mixed Sprouts (2024)
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Thermal Inactivation of Escherichia Phage OSYSP and Host Strain Escherichia coli O157:H7 EDL933: A Comparative Kinetic Analysis (2024)
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Lytic Escherichia phage OSYSP acts additively and synergistically with gaseous ozone against Escherichia coli O157:H7 on spinach leaves (2023)
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Carbapenem resistance in the food supply chain (2023)
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Cefiderocol Resistance in Klebsiella pneumoniae Is Linked to SHV Extended-Spectrum β-Lactamase Activities and Functional Loss of the Outer Membrane Porin OmpK35 (2023)
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Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas (2022)
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Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and β-lactamase activities (2022)
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Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences (2022)
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Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection (2021)
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Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States (2021)
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Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable (2021)
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Applications in food technology: antimicrobial peptides (2021)
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Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing (2020)
Federal Grants 1 $1 total
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Novel linear lipopeptide paenipeptins sensitize multidrug-resistant Gram-negative pathogens to antibiotics - Continuation Year 2020-2021 NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
- Real-Time High Resolution Method for Genomic Surveillance of ESKAPE pathogens NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
- Platelet-Leukocyte Axis in Patients with Chronic Kidney Disease Dialysis Clinic, Inc. Principal Investigator
- Assessment of antibiotic resistance in fresh vegetables from farm to fork National Institute of Food and Agriculture Principal Investigator
Collaboration Network
Top Collaborators
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and β-lactamase activities
- Cefiderocol Resistance in Klebsiella pneumoniae Is Linked to SHV Extended-Spectrum β-Lactamase Activities and Functional Loss of the Outer Membrane Porin OmpK35
- Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i>
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
Showing 5 of 7 shared publications
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and β-lactamase activities
- Treatment-emergent cefiderocol resistance in carbapenem-resistant <i>Acinetobacter baumannii</i> is associated with insertion sequence IS <i>Aba36</i> in the siderophore receptor <i>pirA</i>
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
- Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas
- Lytic Escherichia phage OSYSP acts additively and synergistically with gaseous ozone against Escherichia coli O157:H7 on spinach leaves
- Applications in food technology: antimicrobial peptides
- Thermal Inactivation of Escherichia Phage OSYSP and Host Strain Escherichia coli O157:H7 EDL933: A Comparative Kinetic Analysis
- Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and β-lactamase activities
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
- Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Carbapenem resistance in the food supply chain
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
- A Multidrug-Resistant Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacter hormaechei Strain from Mixed Sprouts
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Carbapenem resistance in the food supply chain
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
- A Multidrug-Resistant Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacter hormaechei Strain from Mixed Sprouts
- Lytic Escherichia phage OSYSP acts additively and synergistically with gaseous ozone against Escherichia coli O157:H7 on spinach leaves
- Thermal Inactivation of Escherichia Phage OSYSP and Host Strain Escherichia coli O157:H7 EDL933: A Comparative Kinetic Analysis
- Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- A Multidrug-Resistant Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacter hormaechei Strain from Mixed Sprouts
- Carbapenem resistance in the food supply chain
- A Multidrug-Resistant Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacter hormaechei Strain from Mixed Sprouts
- Lytic Escherichia phage OSYSP acts additively and synergistically with gaseous ozone against Escherichia coli O157:H7 on spinach leaves
- Thermal Inactivation of Escherichia Phage OSYSP and Host Strain Escherichia coli O157:H7 EDL933: A Comparative Kinetic Analysis
- Applications in food technology: antimicrobial peptides
- Applications in food technology: antimicrobial peptides
- Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection
- Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection
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