Kathryn L. Brown

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UAMS

Also affiliated: W. L. Gore & Associates (Germany) (2019); The Pirbright Institute (1997); Guy's Hospital (2010–2017); Clark University (2009); Agricultural Research Service (1996); St Thomas' Hospital (2007–2020); The King's College (2010–2016); King's College London (2007–2020); Biotechnology and Biological Sciences Research Council (1997); Research and Studies Telecommunications Centre (2025); Certara (United States) (2025); St. Thomas Hospital (2010); King's College Hospital (2007–2013); Medical Research Council (2015–2016)

16 h-index 44 pubs 866 cited

Research Areas

Biomedical Subjects

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ORCID

OverviewAI-generated summary

Kathryn L. Brown's research focuses on the immune response in solid organ transplantation, particularly in the context of kidney and heart allografts. Her work investigates the role of T-lymphocytes, including CD4+ T cells and Foxp3+ T cells, in processes such as graft rejection and renal fibrosis. Brown has studied the mechanisms of chronic rejection, including the association with lymphatic flow and cellular trafficking, and has explored the coexpression of donor peptide/recipient MHC complexes in relation to direct and indirect pathways of immune response.

Her publications also examine the formation and function of tertiary lymphoid organs in renal allografts, noting their potential association with donor-specific tolerance. Additionally, Brown has investigated the transfer of major histocompatibility complex class II molecules between donor and recipient cells in vivo following transplantation. Her research utilizes animal models, specifically mice, to study these immunological phenomena.

Metrics

h-index: 16
Publications: 44
Citations: 866

Selected Publications

Visual Outcomes in Traumatic Aphakia Corrected with Contact Lens versus Intraocular Lens Implantation – A Retrospective Chart Review (2026)

Clinical ophthalmology DOI OpenAlex

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