Susie L. Brown
Researcher
Also affiliated: Program for Appropriate Technology in Health (1985); University of Kentucky (1987); University of Washington (1985)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Susie L. Brown's research investigates immunological memory, particularly in the context of malaria. Her work explores the heterogeneity of memory B cell populations, specifically IgM+ and IgM– memory B cells, and their capacity to produce class-switched antibodies and germinal center B cells upon rechallenge with Plasmodium yoelii. Brown also studies the role of non-canonical DNA structures, such as G-quadruplex and i-motif DNA, in gene regulation, examining their formation in the promoter region of MYD88, a key innate immune adaptor. Her research network includes collaborators Jason S. Stumhofer, Jonathan J. Bauer, Juhyung Lee, and Enatha Ntirandekura, all from the University of Arkansas for Medical Sciences, with whom she has co-authored multiple publications. Brown's scholarly output includes 9 publications with an h-index of 6 and 337 total citations.
Metrics
- h-index: 7
- Publications: 9
- Citations: 348
Selected Publications
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G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88 (2025)
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IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i> (2022)
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IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i> (2021)
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The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure (2021)
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NK1.1 Expression Defines a Population of CD4+ Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Plasmodium yoelii Infection (2018)
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IL-17 Promotes Differentiation of Splenic LSK− Lymphoid Progenitors into B Cells following <i>Plasmodium yoelii</i> Infection (2017)
Collaboration Network
Top Collaborators
- The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i>
- IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i>
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
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