Marie Burdine

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Assistant Professor

UAMS

Also affiliated: University of Arkansas Medical Center (2024); Harold C. Simmons Comprehensive Cancer Center (2010); Arkansas Children's Research Institute (2019–2026); The University of Texas Southwestern Medical Center (2010–2012)

8 h-index 33 pubs 393 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Marie Burdine's research investigates molecular mechanisms underlying immune responses and tissue transplantation. Her work has explored the role of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) in immune cell activation, specifically its control of interleukin-2 production in T lymphocytes and stabilization of the transcription factor Egr1 in activated immune cells. Burdine has also examined the impact of DNA-PKcs inhibition on allogeneic skin graft survival, suggesting its potential relevance in transplantation research. Her publications also include studies on the proteome of plasma fractions from stored red blood cells and changes in the plasma proteome of non-human primates following total body irradiation, indicating an interest in biomarker discovery. Additionally, her research has touched upon the effects of maternal diet on fetal development, specifically investigating SIRT1 histone and protein deacetylase activity in non-human primates, and exploring novel endoplasmic reticulum complexes regulating collagen lysyl hydroxylation in mice.

Metrics

h-index: 8
Publications: 33
Citations: 393

Positions

Assistant Professor publications 2012–2026

University of Arkansas for Medical Sciences Institution web page

Selected Publications

Acellular normothermic spleen perfusion resolves transcriptional and non-transcriptional mechanisms of steroid immunosuppression (2026)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
A step-by-step protocol for isolation and flow cytometry analysis of porcine cardiac valve leaflets (2025)

STAR Protocols DOI OpenAlex
DNA-PKcs phosphorylates LAT impacting its localization to the immune synapse and downstream signaling in CD4+ and CD8+ T cells 2409 (2025)

The Journal of Immunology DOI OpenAlex
A functional surface display system in Saccharomyces boulardii for protein absorption in simulated intestinal fluids (2025)

iScience 1 citation DOI OpenAlex
DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling (2025)

SSRN Electronic Journal DOI OpenAlex
DNA-PKcs governs LAT-dependent signaling in CD4 + and CD8 + T cells (2025)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Kidney Utilization in the Context of a Shifting Donor Landscape in the United States (2024)

Transplantation 4 citations DOI OpenAlex
Intra-peritoneal Povidone-iodine Irrigation Decreases Abscesses in a Perforated Appendicitis Murine Model (2024)

Journal of Pediatric Surgery 2 citations DOI OpenAlex
The use of DNAPK inhibitors increases the efficacy of Lentiviral vectors and decreases off-target effects. (2024)

The Journal of Immunology DOI OpenAlex
Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441 (2024)

Scientific Reports 3 citations DOI OpenAlex
Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells (2023)

Immunology and Cell Biology 7 citations DOI OpenAlex
DNA-PKcs is required for the activation and cytotoxicity of CD8+ effector T cells (2022)

The Journal of Immunology DOI OpenAlex
Impact of Prolonged Cold Ischemia Time on One Year Kidney Transplant Outcomes (2022)

Transplantation Proceedings 8 citations DOI OpenAlex
Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells (2022)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
DNA-PKcs Inhibition Extends Allogeneic Skin Graft Survival (2021)

The Journal of Immunology 1 citation DOI OpenAlex