Laura Osborn

Researcher

UAMS

Also affiliated: Arkansas Children's Hospital (2026); Ave Maria University (2020)

Faculty Researcher

2 h-index 16 pubs 26 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Laura Osborn's research investigates the impact of early life stress on skeletal health and pain sensitivity in offspring. Her work has explored how maternal stress during lactation can affect bone density in young rats, and how early life stress influences postsurgical pain outcomes. Osborn also studies the effects of stress on the gut microbiome composition and maternal care behaviors in adult offspring, examining their impact on mechanical sensitivity. Additionally, her publications include research on paclitaxel-induced peripheral neuropathy in mice, focusing on myelin degradation as a driver of cold hypersensitivity and exploring the metabolism of synthetic cannabinoids in liver microsomes.

Metrics

h-index: 2
Publications: 16
Citations: 26

Selected Publications

Degraded myelin is associated with cold hypersensitivity in paclitaxel-induced peripheral neuropathy (2026)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Impact of Early Life Stress on the Composition of Gut Microbiome (2026)

Journal of Pain DOI OpenAlex
A Novel Model of Paclitaxel-Induced Peripheral Neuropathy Produces aClinically Relevant Phenotype in Mice (2026)

Current Neuropharmacology 2 citations DOI OpenAlex
Stress During Lactation: A Hidden Link to Offspring Bone Health (2025)

Calcified Tissue International 1 citation DOI OpenAlex
Impact of Maternal Care Behaviors on Mechanical Sensitivity of Adult Offspring (2025)

Journal of Pain DOI OpenAlex
Effect of Early Life Stress on Skeletal Health (2024)

Current Developments in Nutrition DOI OpenAlex
Behavioral Effects of Repeated Paclitaxel Cycles on Paclitaxel-Induced Peripheral Neuropathy Resolution (2024)

Journal of Pain DOI OpenAlex
The Persistence Of Rodent Mechanical Hypersensitivity Following Chronic Constriction Injury From Chronic Early-Life Stress (2024)

Journal of Pain DOI OpenAlex
Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes (2022)

Metabolites 2 citations DOI OpenAlex
Methamphetamine‐Induced Proteomic Changes Within the Neuroinflammatory TLR4 Pathway Persist After Long‐Term Self‐Administration in Rats (2022)

The FASEB Journal DOI OpenAlex
Dual mechanisms suppress meloxicam bioactivation relative to sudoxicam (2020)

Toxicology 20 citations DOI OpenAlex