Valeriy V. Lyzogubov

High Impact

Instructor

UAMS primary UA Little Rock

Also affiliated: Pennington Biomedical Research Center (2006–2007); Louisiana State University System (2006–2007); Louisiana State University (2007); University of Arkansas Medical Center (2011–2012); R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology (2005)

23 h-index 56 pubs 1,932 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group

OverviewAI-generated summary

Valeriy V. Lyzogubov's research focuses on investigating disease mechanisms and potential therapeutic interventions, particularly in the context of diabetes-related complications and neurological disorders. He has explored the role of poly(ADP-ribose) polymerase (PARP) inhibition in alleviating experimental diabetic sensory neuropathy and counteracting intraepidermal nerve fiber loss. His work has also examined the impact of nitrosative stress in leptin-deficient mice with advanced diabetic neuropathy and the effects of peroxynitrite decomposition catalysts in diabetic mice.

Further research interests include the development of animal models for specific conditions. Lyzogubov has contributed to the creation of a polyethylene glycol (PEG)-induced mouse model of choroidal neovascularization. His studies have also involved investigating high-fat diet-induced neuropathy in pre-diabetes and obesity, as well as the characteristics of the leptin-deficient (ob/ob) mouse. He leads a research group and has a publication record of 56 articles, with 1,933 citations and an h-index of 23. Key collaborators include Nalini S. Bora, Connor Logan, Reece Mitchell, and Samuel G. Mackintosh, all from the University of Arkansas for Medical Sciences.

Metrics

h-index: 23
Publications: 56
Citations: 1,932

Positions

Instructor publications 2007–2024

University of Arkansas for Medical Sciences Institution web page

Selected Publications

Age-Related Macular Degeneration Models Induced by Polyethylene Glycol (PEG) (2024)

DOI OpenAlex
Role of Complement in the Ocular Immune Response (2024)

Elsevier eBooks DOI OpenAlex
Wet and Dry Age-Related Macular Degeneration Induced by Polyethylene Glycol (2023)

Preprints.org 3 citations DOI OpenAlex
Role of Adiponectin Peptide I (APNp1) in Age-Related Macular Degeneration (2022)

Biomolecules 11 citations DOI OpenAlex
PHF19 inhibition as a therapeutic target in multiple myeloma (2021)

Current Research in Translational Medicine 9 citations DOI OpenAlex
Role of thalidomide, senicapoc, and sodium butyrate in choroidal neovascularization (2020)

Biochemical and Biophysical Research Communications 8 citations DOI OpenAlex
Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns (2020)

Blood Cancer Journal 41 citations DOI OpenAlex
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease (2020)

Leukemia 57 citations DOI OpenAlex
The Role of PHF19 As a Promoter of Tumorigenicity and Therapeutic Target in Multiple Myeloma (2019)

Blood DOI OpenAlex
Multiple Myeloma DREAM Challenge Reveals Epigenetic Regulator PHF19 As Marker of Aggressive Disease (2019)

bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
High Levels of APOBEC3B Gene Expression Contribute to Poor Prognosis in Multiple Myeloma Patients (2018)

Blood DOI OpenAlex
MAF and NF-κB Signaling Pathways Regulate Expression of APOBEC3B in Multiple Myeloma (2017)

Blood DOI OpenAlex
Effect of aspirin on models of retinal pigment epithelium pathology (2016)

Clinical and Experimental Ophthalmology 3 citations DOI OpenAlex
The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration–Like Phenotype (2016)

American Journal Of Pathology 48 citations DOI OpenAlex
In Vitro Assessment of Moxifloxacin Toxicity to Human Iris Pigment Epithelium (2015)

Investigative Ophthalmology & Visual Science 11 citations OpenAlex