Leiqing Zhang Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
John Brown University
unknown
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Biography and Research Information
OverviewAI-generated summary
Dr. Leiqing Zhang conducts research at John Brown University focusing on cancer-related molecular pathways, sphingolipid metabolism, and immune cell function. Her work spans both cancer therapeutics and the development of novel biomaterials. Recent studies include preclinical investigations of drug combinations for small cell lung cancer and pancreatic cancer. Zhang also explores dental materials, with publications describing hydroxypropylmethylcellulose films for biomimetic mineralization, succinates promoting collagen mineralization, and silica-zirconia coatings for dental zirconia.
Her primary research interests include: cancer, hypoxia, and metabolism.
Metrics
- h-index: 3
- Publications: 5
- Citations: 34
Selected Publications
- Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT (2025) DOI
- A Critical Role for Neutral Sphingomyelinase-2 in Doxorubicin-induced Cardiotoxicity (2025) DOI
- Synergistic anti-tumor activity, reduced pERK, and immuno-stimulatory cytokine profiles with 5-FU or ONC212 plus KRAS G12D inhibitor MRTX1133 in CRC and pancreatic cancer cells independent of G12D mutation (2023) DOI
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