Lisa K. Brents

Assistant Professor

UAMS primary Arkansas State University University of Arkansas

Also affiliated: Texas A&M Health Science Center (2012); Arkansas Children's Hospital (2012); University of Michigan (2012); Cayman Chemical (United States) (2012); Arkansas Cardiology (2012); Arkansas State Crime Laboratory (2012); Arkansas Biosciences Institute (2011); Arkansas Department of Health (2012); Texas A&M University (2012)

Faculty Researcher

18 h-index 52 pubs 1,544 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website UAMS TRI Profile

OverviewAI-generated summary

Lisa K. Brents' research investigates substance abuse, maternal and infant health, and animal models of addiction and withdrawal. Her work has explored the impact of environmental factors, such as limited bedding, on ethanol consumption in female rats. She has also examined the pharmacodynamic properties and metabolic resistance of deuterated buprenorphine, as well as its interaction with norbuprenorphine in neonatal opioid withdrawal syndrome. Brents has further investigated the effects of fentanyl in pregnant rats using deuterated buprenorphine. Her publications also include analyses of public responses to FDA inquiries regarding kratom scheduling and the motives for kratom self-medication. Brents has a h-index of 17 and has published 52 papers, accumulating over 1,500 citations. She has a history of collaboration with researchers at the University of Arkansas for Medical Sciences, including Brian J. Parks, Julia Tobacyk, Kyounghyun Kim, and Michael D. Berquist.

Metrics

h-index: 18
Publications: 52
Citations: 1,544

Selected Publications

Deuterated Buprenorphine Mitigates Fentanyl Effects in Pregnant Rats (2024)

Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
Limited bedding and nesting increases ethanol drinking in female rats (2024)

Pharmacology Biochemistry and Behavior 10 citations DOI OpenAlex
Interaction between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome (2023)

Drug and Alcohol Dependence 3 citations DOI OpenAlex
Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats (2023)

Frontiers in Pharmacology 4 citations DOI OpenAlex
Effects of a two-hit model of early life adversity on oral ethanol self-administration and adrenergic receptor expression in adolescent rats (2023)

Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex
481 Interactions between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome (2023)

Journal of Clinical and Translational Science DOI OpenAlex
Response to article – alternative interpretation of “there is reduced immunohistochemical staining of placental aromatase in severe neonatal opioid withdrawal syndrome” (2023)

The Journal of Maternal-Fetal & Neonatal Medicine DOI OpenAlex
Interaction between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome. (2022)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats (2022)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Qualitative content analysis of public responses to an FDA inquiry on the impact of scheduling changes to kratom (2022)

International Journal of Drug Policy 18 citations DOI OpenAlex
Effects of prenatal opioid exposure and early life adversity on opioid‐induced antinociception (2022)

The FASEB Journal DOI OpenAlex
384 Motives for kratom self-medication: contents of public comments solicited by the FDA (2022)

Journal of Clinical and Translational Science 1 citation DOI OpenAlex
Automated quantification of opioid withdrawal in neonatal rat pups using Ethovision® XT software (2021)

Neurotoxicology and Teratology 15 citations DOI OpenAlex
Automated Quantification of Opioid Withdrawal Severity in Neonatal Rat Pups Using Ethovision® XT Software (2020)

The FASEB Journal DOI OpenAlex
The Effects of P‐glycoprotein Inhibition on Norbuprenorphine‐induced Neonatal Abstinence Syndrome (NAS) (2019)

The FASEB Journal DOI OpenAlex

View all publications on OpenAlex →

Grants & Funding

As listed on this researcher's institutional profile.

Fellow-to-Faculty Award UAMS Tobacco
Post Doc Support UAMS
No FP attached (Funded by: UAMS Intramural Grant (CTSA))
Translational Training in Addiction NIH
The Metabolic and Pharmacodynamic Profile of Deuterated Buprenorphine UAMS CTSA
The Role of Norbuprenorphine in the Development of Neonatal Abstinence Syndrome UAMS College of Medicine
RSPGACH 17-DN-10 UAMS College of Medicine
Use of precision deuteration to determine the contribution of norbuprenorphine to buprenorphine-associated neonatal abstinence syndrome NIH