A
Alexander W. Alund Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
faculty
9 h-index
16 pubs
195 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Alexander W. Alund's research investigates the mutagenicity and genotoxicity of various substances, including nanoparticles and ethanol. His work employs whole-genome sequencing in model organisms such as mouse lymphoma cells and *Caenorhabditis elegans* to detect mutations at ultralow frequencies. Alund has also explored the effects of prenatal exposure to ethanol, examining delayed developmental impacts. His research extends to the pharmacodynamics and metabolism of deuterated compounds, specifically buprenorphine, in rats, noting their resistance to metabolism into active metabolites. Alund has a h-index of 9, with 16 total publications and 190 citations. He has collaborated with researchers from the University of Arkansas for Medical Sciences, including Lisa K. Brents, Jeffery H. Moran, and Brian J. Parks, as well as Bohu Pan from the National Center for Toxicological Research, with multiple shared publications.
Metrics
- h-index: 9
- Publications: 16
- Citations: 195
Selected Publications
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Genotoxicity of nanoparticles evaluated using the <i>in vitro</i> micronucleus assay, a review of recent data <sup>§</sup> (2025)
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Evaluation of mutagenic susceptibility of different stages in germ cell development of Caenorhabditis elegans using whole genome sequencing (2023)
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Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma <scp>L5178Y</scp> cells and <i>Caenorhabditis elegans</i> worms by <scp>PacBio</scp> sequencing (2022)
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Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells (2021)
Collaboration Network
Top Collaborators
Jian Yan
United States Food and Drug Administration (US)
3 shared publications
- Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma <scp>L5178Y</scp> cells and <i>Caenorhabditis elegans</i> worms by <scp>PacBio</scp> sequencing
- Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells
- Evaluation of mutagenic susceptibility of different stages in germ cell development of Caenorhabditis elegans using whole genome sequencing
Bohu Pan
National Center for Toxicological Research
2 shared publications
In database
- Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells
- Evaluation of mutagenic susceptibility of different stages in germ cell development of Caenorhabditis elegans using whole genome sequencing
Hua Du
United States Food and Drug Administration (US)
2 shared publications
- Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells
- Evaluation of mutagenic susceptibility of different stages in germ cell development of Caenorhabditis elegans using whole genome sequencing
Timothy W. Robison
Center for Drug Evaluation and Research (US)
2 shared publications
- Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells
- Evaluation of mutagenic susceptibility of different stages in germ cell development of Caenorhabditis elegans using whole genome sequencing
Venumadhav Janganati
University of Arkansas for Medical Sciences (US)
2 shared publications
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Paloma Salazar
University of Arkansas for Medical Sciences (US)
2 shared publications
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Brian J. Parks
University of Arkansas for Medical Sciences
2 shared publications
In database
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Gregory S. Gorman
Samford University (US)
2 shared publications
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Paul L. Prather
University of Arkansas for Medical Sciences (US)
2 shared publications
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Eric C. Peterson
University of Arkansas for Medical Sciences (US)
2 shared publications
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Jeffery H. Moran
University of Arkansas for Medical Sciences
2 shared publications
In database
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Peter A. Crooks
University of Arkansas for Medical Sciences
2 shared publications
In database
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Lisa K. Brents
University of Arkansas for Medical Sciences
2 shared publications
In database
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
- Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Pravin R. Kaldhone
National Center for Toxicological Research (US)
1 shared publication
- Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells
Xiaoqing Guo
National Center for Toxicological Research
1 shared publication
In database
- Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells
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