Madison McGraw

Researcher

University of Arkansas for Medical Sciences

faculty

3 h-index 11 pubs 32 cited

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Biography and Research Information

OverviewAI-generated summary

Madison McGraw's research investigates mechanisms underlying kidney injury and transplantation, with a particular focus on the role of complement pathways and ischemia-reperfusion injury (IRI). Studies have examined how cold storage impacts complement activation in transplanted kidneys and how genetic modifications, such as complement 5 knockout, may mitigate IRI-induced kidney injury in rat models. Further work explores the effects of different preservation methods, like hypothermic machine perfusion compared to static cold storage, on mitigating oxidative stress and tubular injury in rat kidneys. McGraw also studies the influence of environmental enrichment and bedding on ethanol consumption in female rats, suggesting a connection between behavioral and physiological responses. Their work includes collaborations with Nirmala Parajuli, Dinesh Bhattarai, Seongok Lee, and Michael D. Berquist at the University of Arkansas for Medical Sciences, with whom they have co-authored multiple publications.

Metrics

  • h-index: 3
  • Publications: 11
  • Citations: 32

Selected Publications

  • Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats (2025) DOI
  • Compared with Static Cold Storage, Hypothermic Machine Perfusion Mitigates Oxidative Stress and Tubular Injury in Rat Kidneys (2025) DOI
  • Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat (2025) DOI
  • Ischemia and Reperfusion (IRI)-Induced Kidney Injury Is Attenuated by Complement 5 Gene Deletion (Abstract ID: 161749) (2025) DOI
  • Cold Storage Exacerbates Complement Pathway Activation in Kidneys following Transplantation (2024) DOI
  • Limited bedding and nesting increases ethanol drinking in female rats (2024) DOI
  • Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model (2023) DOI
  • Effects of a two-hit model of early life adversity on oral ethanol self-administration and adrenergic receptor expression in adolescent rats (2023) DOI
  • Cold Storage Followed by Transplantation Induces Interferon-Gamma and STAT-1 in Kidney Grafts (2023) DOI
  • Methamphetamine‐Induced Proteomic Changes Within the Neuroinflammatory TLR4 Pathway Persist After Long‐Term Self‐Administration in Rats (2022) DOI
  • 16S rRNA Gene-Based Metagenomic Analysis of Rhizosphere Soil Bacteria in Arkansas Rice Crop Fields (2022) DOI

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