Biography and Research Information
OverviewAI-generated summary
Prathyusha Bagam's research investigates the molecular mechanisms underlying inflammatory responses and their connection to disease, particularly in the context of environmental exposures and cellular processes. Her work includes studies on the proteome and lipid profiles of membrane rafts in A549 cells exposed to e-cigarette vapor condensate, examining the impact on inflammatory responses. Bagam also investigates the role of pentachlorophenol in mediating the regulation of damage-associated molecular patterns (DAMPs) and inflammation in vitro. Her research extends to the application of induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) for predicting drug-induced cardiotoxicity, with a recent proof-of-concept study involving doxorubicin. Bagam has published 12 papers, with an h-index of 9 and 433 total citations. She has collaborated with researchers at the National Center for Toxicological Research, including Li Pang, Vikrant Vijay, William B. Mattes, and Katy S Papineau.
Metrics
- h-index: 9
- Publications: 12
- Citations: 446
Selected Publications
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Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin (2024)
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NADPH oxidase family proteins: signaling dynamics to disease management (2022)
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Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs (2022)
Collaboration Network
Top Collaborators
Rizwana Begum
Southern University and Agricultural and Mechanical College (US)
3 shared publications
- NADPH oxidase family proteins: signaling dynamics to disease management
- E-cig vapor condensate alters proteome and lipid profiles of membrane rafts: impact on inflammatory responses in A549 cells
- Pentachlorophenol mediated regulation of DAMPs and inflammation: In vitro study
Gagandeep Kaur
Southern University and Agricultural and Mechanical College (US)
3 shared publications
- NADPH oxidase family proteins: signaling dynamics to disease management
- E-cig vapor condensate alters proteome and lipid profiles of membrane rafts: impact on inflammatory responses in A549 cells
- Pentachlorophenol mediated regulation of DAMPs and inflammation: In vitro study
Sanjay Batra
Southern University and Agricultural and Mechanical College (US)
2 shared publications
- NADPH oxidase family proteins: signaling dynamics to disease management
- E-cig vapor condensate alters proteome and lipid profiles of membrane rafts: impact on inflammatory responses in A549 cells
Li Pang
United States Food and Drug Administration
2 shared publications
In database
- Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs
- Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin
Shilpa Thota
Southern University and Agricultural and Mechanical College (US)
2 shared publications
- NADPH oxidase family proteins: signaling dynamics to disease management
- Pentachlorophenol mediated regulation of DAMPs and inflammation: In vitro study
Dhirendra Singh
Southern University and Agricultural and Mechanical College (US)
1 shared publication
- E-cig vapor condensate alters proteome and lipid profiles of membrane rafts: impact on inflammatory responses in A549 cells
Devaiah Kambiranda
Southern University and Agricultural and Mechanical College (US)
1 shared publication
- E-cig vapor condensate alters proteome and lipid profiles of membrane rafts: impact on inflammatory responses in A549 cells
Rakesh K. Singh
Florida A&M University - Florida State University College of Engineering (US)
1 shared publication
- E-cig vapor condensate alters proteome and lipid profiles of membrane rafts: impact on inflammatory responses in A549 cells
Wei Feng
United States Food and Drug Administration (US)
1 shared publication
- Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs
Lisa Pence
United States Food and Drug Administration
1 shared publication
In database
- Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs
Kellie A. Woodling
United States Food and Drug Administration
1 shared publication
In database
- Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs
Richard D. Beger
National Center for Toxicological Research
1 shared publication
In database
- Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs
Gonçalo Gamboa da Costa
United States Food and Drug Administration
1 shared publication
In database
- Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs
Waneene C. Dorsey
Grambling State University (US)
1 shared publication
- Pentachlorophenol mediated regulation of DAMPs and inflammation: In vitro study
Sanjay Batra
Southern University and Agricultural and Mechanical College (US)
1 shared publication
- Pentachlorophenol mediated regulation of DAMPs and inflammation: In vitro study
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