Made Harumi Padmaswari
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Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Made Harumi Padmaswari's research focuses on developing gene editing strategies for Duchenne muscular dystrophy (DMD). Her work investigates the challenges associated with delivering CRISPR-Cas9 genome editing tools to treat this genetic disorder, specifically exploring exon skipping as a therapeutic approach. Padmaswari has published on optimizing recombinant Cas9 expression for enhanced protein purification and genome editing applications. Her research also examines the precision and efficacy of RNA-guided DNA integration in muscle cells and the complex genomic and transcriptomic changes that can occur following AAV-CRISPR therapy for DMD. She collaborates with researchers at the University of Arkansas at Fayetteville, including Christopher E. Nelson and Shilpi Agrawal, and has authored six publications with them.
Metrics
- h-index: 3
- Publications: 6
- Citations: 34
Selected Publications
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Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy (2025)
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Preclinical development of genome editing to treat Duchenne muscular dystrophy by exon skipping (2025)
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Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci (2024)
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Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing (2024)
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Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci (2024)
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Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy (2023)
Collaboration Network
Top Collaborators
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Preclinical development of genome editing to treat Duchenne muscular dystrophy by exon skipping
Showing 5 of 6 shared publications
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Preclinical development of genome editing to treat Duchenne muscular dystrophy by exon skipping
Showing 5 of 6 shared publications
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
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