Shilpi Agrawal
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Postdoctoral Research Scientist III
Also affiliated: University of North Carolina at Chapel Hill (2024); North Carolina State University (2024); Vellore Institute of Technology University (2016)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Shilpi Agrawal's research focuses on understanding molecular mechanisms related to cell signaling and drug targeting, particularly involving fibroblast growth factors (FGFs). Her work has investigated the binding affinities of molecules using computational methods, such as restrained umbrella sampling simulations, and explored the role of FGFs in cell proliferation and signaling pathways. Agrawal has also contributed to research on photocatalysts for environmental remediation, specifically the degradation of organic pollutants using modified graphitic carbon nitride materials. Additionally, her research has touched upon the use of aptamers in immunological applications and the evaluation of plant extracts for antioxidant properties in animal models. Her scholarly output includes 59 publications, with an h-index of 12 and 586 citations. Agrawal has collaborated with several researchers at the University of Arkansas at Fayetteville, including Christopher E. Nelson, Thallapuranam Krishnaswamy Suresh Kumar, Made Harumi Padmaswari, and Mahmoud Moradi.
Metrics
- h-index: 11
- Publications: 36
- Citations: 346
Positions
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Postdoctoral Research Scientist III 2021–presentUniversity of Arkansas at Fayetteville Biomedical enginnering ORCID
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Graduate student 2016–2020University of Arkansas Chemistry and Biochemistry ORCID
Selected Publications
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Charge reversal in the heparin-binding pocket enhances the stability and activity of the human FGF1 (2026)
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Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy (2025)
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Standardizing a Protocol for Streamlined Synthesis and Characterization of Lipid Nanoparticles to Enable Preclinical Research and Education (2025)
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A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct (2025)
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Unraveling Attention-Deficit/Hyperactivity Disorder Etiology: Current Challenges and Future Directions in Treatment (2025)
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Preclinical development of genome editing to treat Duchenne muscular dystrophy by exon skipping (2025)
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Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant? (2024)
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Advancing CRISPR-Based Solutions for COVID-19 Diagnosis and Therapeutics (2024)
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Resistance to Acetyl Coenzyme A Carboxylase (ACCase) Inhibitor in Lolium multiflorum: Effect of Multiple Target-Site Mutations (2024)
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Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci (2024)
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Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing (2024)
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Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci (2024)
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CRISPR-Cas9 Unleashed: Gene-Slicing Adventures in the Cancer Battlefield (2024)
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Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy (2023)
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Overexpression and cell-penetrating peptide-mediated delivery of Cas9 and its variant(s) for targeted genome editing (2023)
Collaboration Network
Top Collaborators
- Binding affinity estimation from restrained umbrella sampling simulations
- DNA aptamer-based rolling circle amplification product as a novel immunological adjuvant
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
- Biocompatible, Injectable Anionic Hydrogels Based on Poly(Oligo Ethylene Glycol Monoacrylate‐co‐Acrylic Acid) for Protein Delivery
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
Showing 5 of 16 shared publications
- Binding affinity estimation from restrained umbrella sampling simulations
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Binding Affinity Estimation from Restrained Umbrella Sampling Simulations
Showing 5 of 9 shared publications
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Resistance to Acetyl Coenzyme A Carboxylase (ACCase) Inhibitor in Lolium multiflorum: Effect of Multiple Target-Site Mutations
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
Showing 5 of 9 shared publications
- Binding affinity estimation from restrained umbrella sampling simulations
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Binding Affinity Estimation from Restrained Umbrella Sampling Simulations
Showing 5 of 7 shared publications
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
- Biocompatible, Injectable Anionic Hydrogels Based on Poly(Oligo Ethylene Glycol Monoacrylate‐co‐Acrylic Acid) for Protein Delivery
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Probing the role of proline −135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor
- Heparin-Binding Affinity Tag: A Novel Affinity Tag for Simple and Efficient Purification of Recombinant Proteins
Showing 5 of 6 shared publications
- The Saga of Endocrine FGFs
- Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell Signaling
- Stability Comparisons between Natural versus Engineered Archaeal Heat-Shock Proteins
- Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant?
- Stability Comparisons between Natural Archaeal and Engineered Archaeal‐Bacterial Heat‐Shock Protein Subunits (α, β, and β‐cohesin) and their Oligomeric Complexes
Showing 5 of 6 shared publications
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Preclinical development of genome editing to treat Duchenne muscular dystrophy by exon skipping
Showing 5 of 6 shared publications
- The Saga of Endocrine FGFs
- Advancing CRISPR-Based Solutions for COVID-19 Diagnosis and Therapeutics
- Unraveling Attention-Deficit/Hyperactivity Disorder Etiology: Current Challenges and Future Directions in Treatment
- CRISPR-Cas9 Unleashed: Gene-Slicing Adventures in the Cancer Battlefield
- Charge reversal in the heparin-binding pocket enhances the stability and activity of the human FGF1
- Stability Comparisons between Natural versus Engineered Archaeal Heat-Shock Proteins
- Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant?
- Stability Comparisons between Natural Archaeal and Engineered Archaeal‐Bacterial Heat‐Shock Protein Subunits (α, β, and β‐cohesin) and their Oligomeric Complexes
- Stability Comparisons between Natural versus Engineered Archaeal Heat‐Shock Proteins
- Stability Comparisons between Natural versus Engineered Archaeal Heat-Shock Proteins
- Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant?
- Stability Comparisons between Natural Archaeal and Engineered Archaeal‐Bacterial Heat‐Shock Protein Subunits (α, β, and β‐cohesin) and their Oligomeric Complexes
- Stability Comparisons between Natural versus Engineered Archaeal Heat‐Shock Proteins
- Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci
- Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy
- Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing
- Standardizing a Protocol for Streamlined Synthesis and Characterization of Lipid Nanoparticles to Enable Preclinical Research and Education
- Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy
- A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
- Probing the role of proline −135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor
- Charge reversal in the heparin-binding pocket enhances the stability and activity of the human FGF1
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
- Probing the role of proline −135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor
- Charge reversal in the heparin-binding pocket enhances the stability and activity of the human FGF1
- Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell Signaling
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
- Heparin-Binding Affinity Tag: A Novel Affinity Tag for Simple and Efficient Purification of Recombinant Proteins
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