Shilpi Agrawal

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Postdoctoral Research Scientist III

University of Arkansas primary UA Little Rock Arkansas State University

Also affiliated: Jain University (2020); University of North Carolina at Chapel Hill (2024); Udayana University (2017); North Carolina State University (2024); National Institute of Technology Rourkela (2020); Patna Medical College and Hospital (2020); King Abdulaziz University (2019); Chittaranjan National Cancer Institute (2024); Anand Agricultural University (2018); Dr. D. Y. Patil Medical College, Hospital and Research Centre (2020); Dr. Ram Manohar Lohia Institute of Medical Sciences (2022); Father Muller Homoeopathic Medical College (2022–2025); D.Y. Patil University (2020); Dr D Y Patil Dental College & Hospital (2020); B.J. Medical College (2025); Vellore Institute of Technology University (2016–2022); Savitribai Phule Pune University (2016); Parul University (2023)

Postdoc Researcher

12 h-index 60 pubs 570 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Shilpi Agrawal's research focuses on understanding the molecular mechanisms underlying protein stabilization and interactions, with a particular emphasis on fibroblast growth factors (FGFs) and their binding partners like heparin. Her work has employed computational methods, such as restrained umbrella sampling simulations, to estimate binding affinities and elucidate the structural forces that govern protein behavior, including thermal unfolding reversibility. Agrawal has also contributed to research on the delivery of genome editing technologies, such as CRISPR-Cas9, for therapeutic applications, including Duchenne muscular dystrophy and viral infections like SARS-CoV-2. Her recent publications explore advancements in CRISPR-based diagnostic and therapeutic strategies, as well as optimizing the expression of Cas9 proteins for enhanced purification and genome editing efficiency. She has published 59 papers, accumulating 550 citations, and holds an h-index of 11. Agrawal has collaborated extensively with researchers at the University of Arkansas at Fayetteville, including Christopher E. Nelson, Thallapuraina Krishnaswamy Suresh Kumar, Made Harumi Padmaswari, and Mahmoud Moradi.

Metrics

h-index: 12
Publications: 60
Citations: 570

Selected Publications

Charge reversal in the heparin-binding pocket enhances the stability and activity of the human FGF1 (2026)

Biophysical Journal DOI OpenAlex
Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy (2025)

bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
Standardizing a Protocol for Streamlined Synthesis and Characterization of Lipid Nanoparticles to Enable Preclinical Research and Education (2025)

bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct (2025)

BMC Methods DOI OpenAlex
Unraveling Attention-Deficit/Hyperactivity Disorder Etiology: Current Challenges and Future Directions in Treatment (2025)

NeuroSci 8 citations DOI OpenAlex
Preclinical development of genome editing to treat Duchenne muscular dystrophy by exon skipping (2025)

Journal of Neuromuscular Diseases 2 citations DOI OpenAlex
Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant? (2024)

Microorganisms 1 citation DOI OpenAlex
Advancing CRISPR-Based Solutions for COVID-19 Diagnosis and Therapeutics (2024)

Cells 12 citations DOI OpenAlex
Resistance to Acetyl Coenzyme A Carboxylase (ACCase) Inhibitor in Lolium multiflorum: Effect of Multiple Target-Site Mutations (2024)

Agronomy 3 citations DOI OpenAlex
Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci (2024)

Molecular Therapy — Nucleic Acids 2 citations DOI OpenAlex
Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing (2024)

Biomedicines 8 citations DOI OpenAlex
Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci (2024)

bioRxiv (Cold Spring Harbor Laboratory) 3 citations DOI OpenAlex
CRISPR-Cas9 Unleashed: Gene-Slicing Adventures in the Cancer Battlefield (2024)

Cancer Insight 1 citation DOI OpenAlex
Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy (2023)

Biophysics Reviews 14 citations DOI OpenAlex
Overexpression and cell-penetrating peptide-mediated delivery of Cas9 and its variant(s) for targeted genome editing (2023)

Biophysical Journal 2 citations DOI OpenAlex