Marcelo Bigarella
Sourced from institutional research profiles (UAMS TRI or ARA).
Researcher
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Marcelo Bigarella's research focuses on the molecular mechanisms and diagnostic approaches for prostate cancer. He has investigated the role of specific enzymes, such as p300/CBP and SIRT2, in the acetylation of histones within circulating tumor cells, particularly in the context of castration-resistant prostate cancer (CRPC). Bigarella has also explored the impact of 5α-reductase inhibitors on prostate magnetic resonance imaging (MRI) characteristics and their role in cancer detection. His work includes evaluating the utility of PSA kinetics and advanced imaging techniques like 18F-DCFPyL PSMA PET/MRI for improving the detection of clinically significant prostate cancer, especially in men undergoing active surveillance. He has published 18 works with a total of 2 citations and an h-index of 2. His recent collaborations include work with Jaskirat Sethi, Sunny Singh, Yusra B. Medik, and Sehrish Sardar at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 2
- Publications: 18
- Citations: 13
Selected Publications
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Stem Cell Origin of Cancer: Biological Principles and Clinical Strategies for Chemoprevention and Maintenance Therapy in Cancer Care (2025)
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Multidisciplinary management of nonmetastatic locally advanced prostate cancer (T3-4N0M0) (2025)
Collaboration Network
Top Collaborators
- Multidisciplinary management of nonmetastatic locally advanced prostate cancer (T3-4N0M0)
- Multidisciplinary management of nonmetastatic locally advanced prostate cancer (T3-4N0M0)
- Stem Cell Origin of Cancer: Biological Principles and Clinical Strategies for Chemoprevention and Maintenance Therapy in Cancer Care
- Stem Cell Origin of Cancer: Biological Principles and Clinical Strategies for Chemoprevention and Maintenance Therapy in Cancer Care
- Stem Cell Origin of Cancer: Biological Principles and Clinical Strategies for Chemoprevention and Maintenance Therapy in Cancer Care
- Stem Cell Origin of Cancer: Biological Principles and Clinical Strategies for Chemoprevention and Maintenance Therapy in Cancer Care
- Stem Cell Origin of Cancer: Biological Principles and Clinical Strategies for Chemoprevention and Maintenance Therapy in Cancer Care
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