Matthew J. Igoe

Researcher

Last publication 2024 Last refreshed 2026-05-16

unknown

4 h-index 5 pubs 31 cited

Research Areas

OverviewAI-generated summary

Matthew J. Igoe's research investigates cellular metabolism and immune cell function, particularly in the context of cancer. His work utilizes advanced imaging techniques to quantify metabolic changes in macrophages during immune responses and phagocytosis of tumor cells. He has published on the use of autofluorescence imaging to assess endogenous metabolic cofactors in stimulated macrophages. Igoe also studies the development of multicellular tumor spheroids, analyzing their structural and metabolic characteristics. His research explores the role of CD47 in macrophage function and its implications for cancer therapy. He has collaborated with Shelby N. Bess, Timothy J. Muldoon, Gaven K. Smart, and Abby C. Denison on multiple publications.

Metrics

h-index: 4
Publications: 5
Citations: 31

Selected Publications

The Physiological and Therapeutic Role of CD47 in Macrophage Function and Cancer (2024)

5 citations DOI OpenAlex
Scaffold-free development of multicellular tumor spheroids with spatial characterization of structure and metabolic radial profiles (2024)

7 citations DOI OpenAlex
Abstract 5549: Multicellular spheroid structural and metabolic characterization through radial line profiling (2024)

DOI OpenAlex
Live-Cell Imaging Quantifies Changes in Function and Metabolic NADH Autofluorescence During Macrophage-Mediated Phagocytosis of Tumor Cells (2023)

3 citations DOI OpenAlex
Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages (2023)

12 citations DOI OpenAlex