Matthew J. Igoe

Researcher

University of Arkansas

Unknown Researcher

4 h-index 5 pubs 42 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Matthew J. Igoe's research focuses on the function and metabolic changes within macrophages, particularly in the context of cancer. His work investigates how these immune cells interact with tumor cells, examining processes such as phagocytosis and the role of specific cell surface proteins like CD47. Igoe also studies the metabolic activity of macrophages, utilizing autofluorescence imaging to quantify changes in endogenous metabolic cofactors like NADH in response to stimulation and during phagocytic events. His research extends to the development and characterization of multicellular tumor spheroids, analyzing their structure and metabolic profiles. Igoe collaborates with researchers at the University of Arkansas at Fayetteville, including Shelby N. Bess and Timothy J. Muldoon, with whom he has co-authored multiple publications.

Metrics

h-index: 4
Publications: 5
Citations: 42

Selected Publications

The Physiological and Therapeutic Role of CD47 in Macrophage Function and Cancer (2024)

Immunological Investigations 10 citations DOI OpenAlex
Scaffold-free development of multicellular tumor spheroids with spatial characterization of structure and metabolic radial profiles (2024)

In vitro models 13 citations DOI OpenAlex
Abstract 5549: Multicellular spheroid structural and metabolic characterization through radial line profiling (2024)

Cancer Research DOI OpenAlex
Live-Cell Imaging Quantifies Changes in Function and Metabolic NADH Autofluorescence During Macrophage-Mediated Phagocytosis of Tumor Cells (2023)

Immunological Investigations 4 citations DOI OpenAlex
Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages (2023)

Cancer & Metabolism 14 citations DOI OpenAlex