Shelby N. Bess

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Graduate Assistant

University of Arkansas

Also affiliated: University of North Carolina at Chapel Hill (2024); North Carolina State University (2024)

Faculty Researcher

5 h-index 18 pubs 72 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website

OverviewAI-generated summary

Shelby N. Bess's research investigates the role of macrophages in cancer immunotherapy and the development of tumor models. Bess has explored autofluorescence imaging of metabolic cofactors in macrophages stimulated with cytokines and quantified changes in macrophage function and metabolic NADH autofluorescence during tumor cell phagocytosis. A recent publication examined macrophage-targeted anti-CCL2 immunotherapy, enhancing tumor sensitivity to 5-fluorouracil in a murine colon carcinoma model using diffuse reflectance spectroscopy. Bess also contributed to work on the physiological and therapeutic role of CD47 in macrophage function and cancer, as well as scaffold-free development of multicellular tumor spheroids with spatial characterization of metabolic profiles. Further research includes live-cell imaging of macrophage-mediated phagocytosis and minimally invasive endoscopic monitoring of colitis in mice. Bess's work has resulted in 18 publications and 54 citations, with an h-index of 5.

Metrics

h-index: 5
Publications: 18
Citations: 72

Selected Publications

Metabolic Imaging and Characterization of Multicomponent Spheroid Models in Vitro. (2025)

DOI OpenAlex
A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct (2025)

BMC Methods DOI OpenAlex
Quantifying treatment response to a macrophage-targeted therapy in combination with immune checkpoint inhibitors after exposure to conventional chemotherapy (2025)

Frontiers in Immunology DOI OpenAlex
The Physiological and Therapeutic Role of CD47 in Macrophage Function and Cancer (2024)

Immunological Investigations 10 citations DOI OpenAlex
Scaffold-free development of multicellular tumor spheroids with spatial characterization of structure and metabolic radial profiles (2024)

In vitro models 13 citations DOI OpenAlex
Abstract 5549: Multicellular spheroid structural and metabolic characterization through radial line profiling (2024)

Cancer Research DOI OpenAlex
Live-Cell Imaging Quantifies Changes in Function and Metabolic NADH Autofluorescence During Macrophage-Mediated Phagocytosis of Tumor Cells (2023)

Immunological Investigations 4 citations DOI OpenAlex
Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages (2023)

Cancer & Metabolism 14 citations DOI OpenAlex
Minimally invasive in vivo endoscopic monitoring of dextran sulfate sodium-induced murine colitis (2022)

MethodsX 1 citation DOI OpenAlex
Macrophage-targeted anti-CCL2 immunotherapy enhances tumor sensitivity to 5-fluorouracil in a Balb/c-CT26 murine colon carcinoma model measured using diffuse reflectance spectroscopy (2022)

BMC Immunology 13 citations DOI OpenAlex
Abstract P009: Correlation between immune modulation of macrophage recruitment and new blood vessel formation in a subcutaneous murine mouse model of colorectal cancer (2022)

Cancer Immunology Research DOI OpenAlex
Corrigendum to “Efficacy and clinical monitoring strategies for immune checkpoint inhibitors and targeted cytokine immunotherapy for locally advanced and metastatic colorectal cancer” [Cytokine Growth Factor Rev. 49 (2019) 1–9] (2020)

Cytokine & Growth Factor Reviews DOI OpenAlex
Efficacy and clinical monitoring strategies for immune checkpoint inhibitors and targeted cytokine immunotherapy for locally advanced and metastatic colorectal cancer (2019)

Cytokine & Growth Factor Reviews 16 citations DOI OpenAlex
Monitoring therapeutic response of murine tumor allografts of colon carcinoma in response to combined immunotherapy and chemotherapy (Conference Presentation) (2019)

DOI OpenAlex