Shelby N. Bess Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Graduate Assistant

Last publication 2025 Last refreshed 2026-05-16

faculty

5 h-index 18 pubs 60 cited

Biography and Research Information

OverviewAI-generated summary

Shelby N. Bess's research investigates the role of macrophages in cancer immunotherapy and the development of tumor models. Bess has explored autofluorescence imaging of metabolic cofactors in macrophages stimulated with cytokines and quantified changes in macrophage function and metabolic NADH autofluorescence during tumor cell phagocytosis. A recent publication examined macrophage-targeted anti-CCL2 immunotherapy, enhancing tumor sensitivity to 5-fluorouracil in a murine colon carcinoma model using diffuse reflectance spectroscopy. Bess also contributed to work on the physiological and therapeutic role of CD47 in macrophage function and cancer, as well as scaffold-free development of multicellular tumor spheroids with spatial characterization of metabolic profiles. Further research includes live-cell imaging of macrophage-mediated phagocytosis and minimally invasive endoscopic monitoring of colitis in mice. Bess's work has resulted in 18 publications and 54 citations, with an h-index of 5.

Metrics

  • h-index: 5
  • Publications: 18
  • Citations: 60

Selected Publications

  • Metabolic Imaging and Characterization of Multicomponent Spheroid Models in Vitro. (2025)
  • A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct (2025)
  • Quantifying treatment response to a macrophage-targeted therapy in combination with immune checkpoint inhibitors after exposure to conventional chemotherapy (2025)
  • The Physiological and Therapeutic Role of CD47 in Macrophage Function and Cancer (2024)
    5 citations DOI OpenAlex
  • Scaffold-free development of multicellular tumor spheroids with spatial characterization of structure and metabolic radial profiles (2024)
    7 citations DOI OpenAlex
  • Abstract 5549: Multicellular spheroid structural and metabolic characterization through radial line profiling (2024)
  • Live-Cell Imaging Quantifies Changes in Function and Metabolic NADH Autofluorescence During Macrophage-Mediated Phagocytosis of Tumor Cells (2023)
    3 citations DOI OpenAlex
  • Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages (2023)
    12 citations DOI OpenAlex
  • Minimally invasive in vivo endoscopic monitoring of dextran sulfate sodium-induced murine colitis (2022)
    1 citation DOI OpenAlex
  • Macrophage-targeted anti-CCL2 immunotherapy enhances tumor sensitivity to 5-fluorouracil in a Balb/c-CT26 murine colon carcinoma model measured using diffuse reflectance spectroscopy (2022)
    10 citations DOI OpenAlex
  • Abstract P009: Correlation between immune modulation of macrophage recruitment and new blood vessel formation in a subcutaneous murine mouse model of colorectal cancer (2022)

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Collaboration Network

18 Collaborators 1 Institution 1 Country

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