Matthias C. McIntosh
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Also affiliated: Pennsylvania State University (1989–1997); Stanford University (1995–1998)
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Biography and Research Information
OverviewAI-generated summary
Matthias C. McIntosh's research focuses on organic synthesis, particularly the development of new synthetic methodologies and their application in the construction of complex organic molecules. His work has explored various catalytic reactions, including palladium-catalyzed cross-coupling reactions and tandem catalyzed cyclizations for the synthesis of furan and butenolide compounds. He has also investigated rearrangements such as the Ireland and Claisen rearrangements, and developed methods for amide oxidation and Mitsunobu reactions. McIntosh has contributed to the total synthesis of natural products, including approaches to conduritols, cyclitols, and diterpenes like Cladiell-11-ene-3,6,7-triol. His research has been documented in numerous publications, and his scholarly contributions are reflected in an h-index of 19 and over 1,200 citations.
Metrics
- h-index: 19
- Publications: 64
- Citations: 1,203
Selected Publications
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Acyclic 1,4-Stereocontrol via the Allylic Diazene Rearrangement: Development, Applications, and the Essential Role of Kinetic E Stereoselectivity in Tosylhydrazone Formation (2017)
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ChemInform Abstract: Radical [1,3] Rearrangements of Breslow Intermediates. (2016)
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Radical [1,3] Rearrangements of Breslow Intermediates (2015)
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Radical [1,3] Rearrangements of Breslow Intermediates (2015)
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ChemInform Abstract: Intercepting the Breslow Intermediate via Claisen Rearrangement: Synthesis of Complex Tertiary Alcohols Without Organometallic Reagents. (2013)
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Anomalies in the asymmetric transfer hydrogenation of several polycyclic meso compounds (2012)
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Intercepting the Breslow Intermediate via Claisen Rearrangement: Synthesis of Complex Tertiary Alcohols without Organometallic Reagents (2012)
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Efficient, scalable asymmetric synthesis of an epoxy quinol via Noyori desymmetrization of a meso diketone (2011)
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Synthesis of the C21–C34 fragment of antascomicin B (2011)
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ChemInform Abstract: Synthesis and Anticancer Activity of Sclerophytin‐Inspired Hydroisobenzofurans. (2010)
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Studies directed toward the synthesis of the massileunicellins. Part 2 (2010)
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Synthesis and anticancer activity of sclerophytin-inspired hydroisobenzofurans (2009)
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ChemInform Abstract: Acyclic 1,4‐Stereocontrol via Reductive 1,3‐Transpositions. (2008)
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Toward the synthesis of antascomicin B. Synthesis of a model of the C22–C34 fragment via Ireland–Claisen and allylic diazene rearrangements (2008)
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Simplified analogs of sclerophytin A as potential anticancer agents (2007)
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