Pavani Gonnabathula Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Postdoctoral Research Fellow

National Center for Toxicological Research

postdoc

3 h-index 12 pubs 23 cited

Research Areas

Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Carcinogens and Genotoxicity Assessment Forensic Toxicology and Drug Analysis Health and Medical Research Impacts Neuroinflammation and Neurodegeneration Mechanisms Meta-analysis and systematic reviews

Links

ORCID

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OverviewAI-generated summary

Pavani Gonnabathula's research focuses on the application of physiologically-based pharmacokinetic (PBPK) models for toxicological and forensic science purposes. Her work investigates how PBPK models can be utilized to estimate drug metabolism and related absorption, distribution, metabolism, and excretion (ADME) processes, particularly in specific populations. Gonnabathula has explored the utility of life stage-specific chemical risk assessments employing New Approach Methodologies (NAMs) and the application of PBPK models in scenarios such as acute chemical incidents. Additionally, her research has examined the impact of emerging contaminants on biomolecules in mice, specifically investigating the role of peroxisome proliferator-activated receptor-alpha (PPARĪ±). She has also reviewed the impact of sex hormones on cognition and treatment and explored microfluidic devices as replacements for traditional pharmacokinetic study models, particularly in pregnancy-associated drug studies. Gonnabathula collaborates with researchers at the National Center for Toxicological Research, including Kiara Fairman and Me-Kyoung Choi.

Metrics

  • h-index: 3
  • Publications: 12
  • Citations: 23

Selected Publications

  • Applications of PBPK Modeling to Estimate Drug Metabolism and Related ADME Processes in Specific Populations (2025) DOI
  • Microfluidic device successfully replaces traditional models of pregnancy associated drug pharmacokinetic studies (2025) DOI
  • Utility of life stage-specific chemical risk assessments based on New Approach Methodologies (NAMs) (2024) DOI
  • An Overview of Physiologically-Based Pharmacokinetic Models for Forensic Science (2023) DOI

Collaborators

Researchers in the database who share publications

Kiara Fairman National Center for Toxicological Research 3 shared publications Me-Kyoung Choi National Center for Toxicological Research 2 shared publications Suresh K. Nagumalli National Center for Toxicological Research 1 shared publication

Similar Researchers

Based on overlapping research topics

Sasin Payakachat University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Carcinogens and Genotoxicity Assessment
Good match 4 shared topics
Me-Kyoung Choi National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Carcinogens and Genotoxicity Assessment
Good match 4 shared topics
Greg R. Olson National Center for Toxicological Research
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Good match 5 shared topics
Shu-Chieh Hu National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Carcinogens and Genotoxicity Assessment
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Mona I. Churchwell National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Carcinogens and Genotoxicity Assessment
Good match 4 shared topics
Vijayalaskshmi Varma National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Health and Medical Research Impacts
Good match 3 shared topics