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R. Marena Guzman studies host-pathogen interactions, with a particular focus on the bacterium *Coxiella burnetii*, the causative agent of Q fever. Her research utilizes *Drosophila melanogaster* as a model organism to investigate genetic variations that influence host susceptibility and resistance to infection. Recent work has explored the role of the STING protein in *Drosophila* immunity against *Coxiella burnetii*, identifying its function in reducing reactive oxygen species accumulation during infection. Guzman also reviews and advocates for the use of multiple infection models, including in vitro, in vivo, and ex vivo lung models, to advance the understanding and treatment of Q fever. Her scholarship includes 14 publications and 322 citations, with an h-index of 6. She collaborates with researchers such as Daniel E. Voth at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 6
- Publications: 14
- Citations: 326
Selected Publications
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Embracing multiple infection models to tackle Q fever: A review of in vitro, in vivo, and lung ex vivo models (2024)
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- Natural genetic variation in <i>Drosophila melanogaster</i> reveals genes associated with <i>Coxiella burnetii</i> infection
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- Natural genetic variation in <i>Drosophila melanogaster</i> reveals genes associated with <i>Coxiella burnetii</i> infection
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- Natural genetic variation in <i>Drosophila melanogaster</i> reveals genes associated with <i>Coxiella burnetii</i> infection
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- Natural genetic variation in <i>Drosophila melanogaster</i> reveals genes associated with <i>Coxiella burnetii</i> infection
- Natural genetic variation in <i>Drosophila melanogaster</i> reveals genes associated with <i>Coxiella burnetii</i> infection
- Natural genetic variation in <i>Drosophila melanogaster</i> reveals genes associated with <i>Coxiella burnetii</i> infection
- Natural genetic variation in <i>Drosophila melanogaster</i> reveals genes associated with <i>Coxiella burnetii</i> infection
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- <i>Drosophila melanogaster</i> Sting mediates <i>Coxiella burnetii</i> infection by reducing accumulation of reactive oxygen species
- Embracing multiple infection models to tackle Q fever: A review of in vitro, in vivo, and lung ex vivo models
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