Hayden Roys

Researcher

University of Arkansas for Medical Sciences

faculty

4 h-index 19 pubs 106 cited

Research Areas

Microbial infections and disease research Immune Response and Inflammation Molecular Biology Techniques and Applications Immune Cell Function and Interaction Health and Medical Research Impacts

Links

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OverviewAI-generated summary

Hayden Roys' research primarily investigates the cellular and molecular mechanisms underlying parasitic infections, with a particular focus on *Leishmania major* infection in murine models. Roys' work has explored the role of hypoxia-inducible factor (HIF) signaling in macrophage function and its impact on disease progression, including its influence on inflammation and lymphangiogenesis. Investigations have also utilized single-cell resolution transcriptional analysis to understand cellular heterogeneity and transcriptomic alterations within infected tissues. Recent publications examine the link between enhanced translational activity and lymphatic endothelial cell activation in cutaneous leishmaniasis. Roys has co-authored 19 publications, accumulating 106 citations, and holds an h-index of 4. Key collaborators at the University of Arkansas for Medical Sciences include Anne K. Bowlin, Lucy Fry, Gopinath Venugopal, and Charity L. Washam.

Metrics

  • h-index: 4
  • Publications: 19
  • Citations: 106

Selected Publications

  • Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267 (2025) DOI
  • Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells (2025) DOI
  • Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis (2025) DOI
  • Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025) DOI
  • HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2025) DOI
  • HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection (2024) DOI
  • Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs (2024) DOI
  • Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis (2024) DOI
  • Distinct lymphatic remodeling is associated with healing and non-healing murine cutaneous leishmaniasis (2023) DOI
  • In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution (2022) DOI
  • Erratum for Weinkopff et al., “ <i>Leishmania</i> Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner” (2022) DOI
  • HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection (2021) DOI
  • HIF-alpha Activation Impacts Macrophage Function During Murine &lt;em&gt;Leishmania major&lt;/em&gt; Infection (2021) DOI
  • In vivo reprogramming of murine host immune response genes following Leishmania major infection (2021) DOI
  • Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection (2021) DOI

Collaborators

Researchers in the database who share publications

Anne K. Bowlin University of Arkansas for Medical Sciences 18 shared publications Lucy Fry University of Arkansas for Medical Sciences 14 shared publications Gopinath Venugopal University of Arkansas for Medical Sciences 11 shared publications Charity L. Washam University of Arkansas for Medical Sciences 8 shared publications Alexx Weaver University of Arkansas for Medical Sciences 4 shared publications Manjunath Bettadapura University of Arkansas for Medical Sciences 3 shared publications Humphrey Wanjala University of Arkansas at Pine Bluff 3 shared publications Steven Murdock University of Arkansas for Medical Sciences 2 shared publications

Similar Researchers

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Lucy Fry University of Arkansas for Medical Sciences
Microbial infections and disease research Immune Response and Inflammation Molecular Biology Techniques and Applications
Strong match 5 shared topics
Gopinath Venugopal University of Arkansas for Medical Sciences
Microbial infections and disease research Immune Response and Inflammation Molecular Biology Techniques and Applications
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Manjunath Bettadapura University of Arkansas for Medical Sciences
Microbial infections and disease research Immune Response and Inflammation Immune Cell Function and Interaction
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Matthew Jorgenson University of Arkansas for Medical Sciences
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Richard Connor University of Arkansas for Medical Sciences
Microbial infections and disease research Immune Response and Inflammation Molecular Biology Techniques and Applications
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Huang, Lu University of Arkansas for Medical Sciences
Microbial infections and disease research Immune Response and Inflammation Immune Cell Function and Interaction
Strong match 4 shared topics