Samir V. Jenkins
Researcher
Also affiliated: United States Food and Drug Administration (2015); Cornell University (2019); Yale University (2008); Sterling Research Group (2008); Radiation Oncology Institute (2023); Winthrop Rockefeller Foundation (2019–2025); ORCID (2020); Radiation Oncology Associates (2023)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Samir V. Jenkins' research focuses on the application of nanomaterials in therapeutic and diagnostic contexts, particularly in cancer treatment. His work investigates the photothermal properties of gold nanostructures and their conversion into self-assembled ionic nanomaterials for enhanced therapeutic effects. Jenkins has explored the use of nanocage-coated artificial extracellular matrices to promote neural stem cell differentiation and the nanoscale control of photothermal action in gold nanostructure-coated surfaces.
His research also extends to drug delivery systems, including liposome formulations for tumor-targeted delivery in conjunction with radiation therapy. Jenkins has examined the molecular mechanisms underlying cancer progression and dormancy, including the role of specific proteins in inducing reversible dormancy in lung tumor cells and the exosomal profiles of hepatocellular carcinoma cells. He has also investigated bystander effects in spatially fractionated radiation therapy and the proinflammatory activity of VEGF-targeted treatments.
Jenkins leads a research group and collaborates with researchers at the University of Arkansas for Medical Sciences, including Ruud P.M. Dings, Robert Griffin, and Azemat Jamshidi‐Parsian, as well as Narasimhan Rajaram at the University of Arkansas at Fayetteville. His scholarly output is characterized by a high h-index of 21 and over 1,400 citations across 75 publications, designating him as a highly cited researcher.
Metrics
- h-index: 21
- Publications: 75
- Citations: 1,440
Selected Publications
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Synthesis of Peptide Analogs From Fish Venom With Potential Antimicrobial and Anticancer Activity (2026)
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Abstract 4785: Thermal regulation of dysbiotic tumor vasculature (2026)
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Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026)
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CB-839 induces reversible dormancy in lung tumor-cells (2024)
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Interrogating the Role of Endocytosis Pathway and Organelle Trafficking for Doxorubicin-Based Combination Ionic Nanomedicines (2024)
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Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications (2024)
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Abstract 186: Tumor exosome-macrophage interactions: The role of tumor-associated glycans and scavenger receptor class A (2024)
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Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials (2023)
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Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells (2023)
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General principles of SFRT biology (2023)
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Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes (2023)
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Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking (2023)
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Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking (2023)
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Proteomic Analysis of Transcription Factors Involved in the Alteration of Ischemic Mouse Heart as Modulated by MSC Exosomes (2023)
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Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy (2022)
Collaboration Network
Top Collaborators
- Enhanced photothermal heating and combination therapy of NIR dye <i>via</i> conversion to self-assembled ionic nanomaterials
- Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation
- Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells
- Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
Showing 5 of 16 shared publications
- Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation
- Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- CB-839 induces reversible dormancy in lung tumor-cells
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
Showing 5 of 9 shared publications
- Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy
- Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications
- Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces
- CB-839 induces reversible dormancy in lung tumor-cells
- Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors
Showing 5 of 7 shared publications
- Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials
- Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors
- Proteomic Analysis of Transcription Factors Involved in the Alteration of Ischemic Mouse Heart as Modulated by MSC Exosomes
- Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes
- Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation
- Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces
- Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials
- Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells
- Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors
- Enhanced photothermal heating and combination therapy of NIR dye <i>via</i> conversion to self-assembled ionic nanomaterials
- Interrogating the Role of Endocytosis Pathway and Organelle Trafficking for Doxorubicin-Based Combination Ionic Nanomedicines
- Enhanced photothermal heating and combination therapy of NIR dye <i>via</i> conversion to self-assembled ionic nanomaterials
- Interrogating the Role of Endocytosis Pathway and Organelle Trafficking for Doxorubicin-Based Combination Ionic Nanomedicines
- CB-839 induces reversible dormancy in lung tumor-cells
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
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