Match tier Listed
Presence Current · Arkansas
Last published 2021
Sources OpenAlex · ORCID
Refreshed 2026-10-03

Sasin Payakachat

Role not yet determined Is this you? Add your title

UAMS primary Harding University Hendrix College

Also affiliated: Washington University in St. Louis (2020)

2 h-index 3 pubs 20 cited

Research Areas

Biomedical Subjects

  • Anti-Inflammatory Agents, Non-Steroidal
  • Glutathione
  • Humans
  • Microsomes, Liver
  • Activation, Metabolic
  • Chromatography, Liquid
  • Meclofenamic Acid
  • Models, Chemical
  • Spectrometry, Fluorescence
  • Mass Spectrometry
  • Benzoquinones
  • Animals
  • Biological Availability
  • Diphenylamine
  • Kinetics

Links

Research Group

OverviewAI-generated summary

Sasin Payakachat's research focuses on the bioactivation pathways of non-steroidal anti-inflammatory drugs (NSAIDs), specifically those containing the diphenylamine structure. Her work investigates how structural variations within these drugs influence their interaction with metabolic processes, particularly in the liver. Payakachat has published research examining the risks associated with halogenation in diphenylamine NSAIDs and has identified specific pathways through which these compounds can be bioactivated. Her work utilizes analytical techniques such as liquid chromatography and mass spectrometry to characterize these metabolic processes. Collaborators on this research include Grover Miller, Gunnar Boysen, and Benjamin Mark Schleiff from the University of Arkansas for Medical Sciences. Payakachat has a h-index of 2 with 3 total publications and 20 citations.

Metrics

  • h-index: 2
  • Publications: 3
  • Citations: 20

Selected Publications

  • Structural Variations among Marketed Diphenylamine NSAIDs Determine Preference and Efficiency for Four Possible Bioactivation Pathways (2021)
    The FASEB Journal DOI OpenAlex
  • Impacts of diphenylamine NSAID halogenation on bioactivation risks (2021)
    Toxicology 8 citations DOI OpenAlex
  • Significance of Multiple Bioactivation Pathways for Meclofenamate as Revealed through Modeling and Reaction Kinetics (2020)
    Drug Metabolism and Disposition 12 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

8 Collaborators 7 Institutions 1 Country

Top Collaborators

View profile →
View profile →
View profile →
View profile →
View profile →

Similar Researchers

Based on overlapping research topics

Benjamin Mark Schleiff University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Metabolomics and Mass Spectrometry Studies Analytical Chemistry and Chromatography
Strong match 5 shared topics
Samantha Crosby University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Metabolomics and Mass Spectrometry Studies Drug-Induced Hepatotoxicity and Protection
Good match 3 shared topics
Fernando Maia de Oliveira University of Arkansas at Fayetteville
Pharmacological Effects and Toxicity Studies Analytical Chemistry and Chromatography Immune Response and Inflammation
Good match 3 shared topics
Joseph DeLuca University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Analytical Chemistry and Chromatography Drug-Induced Hepatotoxicity and Protection
Good match 3 shared topics
Laura K. Schnackenberg National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Analytical Chemistry and Chromatography Drug-Induced Hepatotoxicity and Protection
Good match 3 shared topics
Xuan Zhang National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Immune Response and Inflammation Drug-Induced Hepatotoxicity and Protection
Good match 3 shared topics