G
Gunnar Boysen Institution-verified
Sourced from institutional research profiles (UAMS TRI or ARA).
Federal Grant PI
High Impact
Associate Professor -tenured
faculty
33 h-index
139 pubs
3,560 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Gunnar Boysen's research investigates the complex interactions between chemical exposures and nutritional or lifestyle factors, such as diet and physical activity. Utilizing DNA and protein adducts, his work examines carcinogen metabolism and how nutritional components modify these processes. He also studies the underlying mechanisms regulating the activity of relevant enzymes. Additionally, Boysen employs targeted and untargeted mass spectrometry-based metabolomic approaches to investigate changes in common metabolic pathways resulting from exposure-related factors.
Boysen leads a research group and has secured federal funding for his work. His research group includes key collaborators from the University of Arkansas for Medical Sciences, such as Grover P. Miller, Azemat Jamshidi‐Parsian, Nadia I. Georgieva, and Intawat Nookaew, with whom he has co-authored multiple publications. His scholarly output includes 137 publications with over 3,500 citations, and he holds an h-index of 33. He has received recognition as a highly cited researcher and as a principal investigator on federal grants.
Metrics
- h-index: 33
- Publications: 139
- Citations: 3,560
Selected Publications
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Sex-Specific Formation of 1,2:3,4-Diepoxybutane-Derived Hemoglobin Adducts in 1,3-Butadiene-Exposed Workers (2025)
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Human health risk assessment for exposures to 1,3-butadiene in the United States with input from an independent science advisory panel (2025)
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Investigating the origins of the mutational signatures in cancer (2025)
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Generation of BT-Amide, a Bone-Targeted Pyk2 Inhibitor, Effective <i>via</i> Oral Administration, for the Prevention of Glucocorticoid-Induced Bone Loss (2024)
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Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance (2023)
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Climate Change and New Challenges for Rural Communities: Particulate Matter Matters (2023)
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Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance (2023)
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Exploiting nanopore sequencing for characterization and grading of <i>IDH</i>‐mutant gliomas (2023)
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Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes (2022)
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Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mice (2022)
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Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences (2022)
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Current and Future Methodology for Quantitation and Site-Specific Mapping the Location of DNA Adducts (2022)
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Current and Future Methodology for Quantitation and Site-specific Mapping the Location of DNA Adducts (2021)
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DEB‐FAPy‐dG Adducts of 1,3‐Butadiene: Synthesis, Structural Characterization, and Formation in 1,2,3,4‐Diepoxybutane Treated DNA** (2021)
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CYP2C9 and 3A4 play opposing roles in bioactivation and detoxification of diphenylamine NSAIDs (2021)
Federal Grants 1 $719,050 total
NIH/National Institute of Environmental Health Sciences
Contact PI
Feb 2025 - Jan 2028
Understanding the origins of the mutational landscape in cancer
Grants & Funding
Collaboration Network
Top Collaborators
Mary A. Schleiff
6 shared publications
- Impacts of diphenylamine NSAID halogenation on bioactivation risks
- CYP2C9 and 3A4 play opposing roles in bioactivation and detoxification of diphenylamine NSAIDs
- Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors
- Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes
- Structural Variations among Marketed Diphenylamine NSAIDs Determine Preference and Efficiency for Four Possible Bioactivation Pathways
Showing 5 of 6 shared publications
Grover P. Miller
6 shared publications
In database
- Impacts of diphenylamine NSAID halogenation on bioactivation risks
- CYP2C9 and 3A4 play opposing roles in bioactivation and detoxification of diphenylamine NSAIDs
- Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors
- Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes
- Structural Variations among Marketed Diphenylamine NSAIDs Determine Preference and Efficiency for Four Possible Bioactivation Pathways
Showing 5 of 6 shared publications
James A. Swenberg
University of North Carolina at Chapel Hill (US)
6 shared publications
- Sex-Specific Formation of 1,2:3,4-Diepoxybutane-Derived Hemoglobin Adducts in 1,3-Butadiene-Exposed Workers
- Low Utilization of Circulating Glucose after Food Withdrawal in Snell Dwarf Mice
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
Showing 5 of 6 shared publications
Intawat Nookaew
University of Arkansas for Medical Sciences
5 shared publications
In database
- Current and Future Methodology for Quantitation and Site-Specific Mapping the Location of DNA Adducts
- Exploiting nanopore sequencing for characterization and grading of <i>IDH</i>‐mutant gliomas
- Investigating the origins of the mutational signatures in cancer
- Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences
- Current and Future Methodology for Quantitation and Site-specific Mapping the Location of DNA Adducts
Nadia I. Georgieva
University of Arkansas for Medical Sciences
5 shared publications
In database
- Sex-Specific Formation of 1,2:3,4-Diepoxybutane-Derived Hemoglobin Adducts in 1,3-Butadiene-Exposed Workers
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
Vernon E. Walker
Cleveland Clinic Lerner College of Medicine (US)
5 shared publications
- Sex-Specific Formation of 1,2:3,4-Diepoxybutane-Derived Hemoglobin Adducts in 1,3-Butadiene-Exposed Workers
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
Azemat Jamshidi‐Parsian
5 shared publications
In database
- Exploiting nanopore sequencing for characterization and grading of <i>IDH</i>‐mutant gliomas
- CB-839 induces reversible dormancy in lung tumor-cells
- Abstract 1088: Acquired radiation resistance induces thiol-dependent cisplatin cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
Patricia B. Upton
4 shared publications
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
Karupiah Jayaraj
4 shared publications
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
Yutai Li
4 shared publications
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Data from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
- Supplementary Table 1 from Analysis of Diepoxide-Specific Cyclic <b><i>N</i></b>-Terminal Globin Adducts in Mice and Rats after Inhalation Exposure to 1,3-Butadiene
Samir V. Jenkins
University of Arkansas for Medical Sciences
4 shared publications
In database
- CB-839 induces reversible dormancy in lung tumor-cells
- Abstract 1088: Acquired radiation resistance induces thiol-dependent cisplatin cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
Robert J. Griffin
4 shared publications
- CB-839 induces reversible dormancy in lung tumor-cells
- Abstract 1088: Acquired radiation resistance induces thiol-dependent cisplatin cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
Ruud P.M. Dings
4 shared publications
In database
- CB-839 induces reversible dormancy in lung tumor-cells
- Abstract 1088: Acquired radiation resistance induces thiol-dependent cisplatin cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
- Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance
S. Joshua Swamidass
Washington University in St. Louis (US)
3 shared publications
- Impacts of diphenylamine NSAID halogenation on bioactivation risks
- Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors
- Structural Variations among Marketed Diphenylamine NSAIDs Determine Preference and Efficiency for Four Possible Bioactivation Pathways
Samantha Crosby
3 shared publications
In database
- CYP2C9 and 3A4 play opposing roles in bioactivation and detoxification of diphenylamine NSAIDs
- Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes
- 5F-APINACA kin&pheno-HLM&MLM.xlsx
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