Yihong Kaufmann
Staff Scientist
Also affiliated: United States Department of Veterans Affairs (2003); University of Arkansas Medical Center (2019); Central Arkansas Veterans Healthcare System (2003–2022); Arkansas Children's Nutrition Center (2025); John L. McClellan Memorial Veterans Hospital (2007); Arkansas Children's Research Institute (2025)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Yihong Kaufmann's research focuses on the mechanisms of disease development and potential therapeutic interventions, often utilizing animal models. Her work has investigated the role of specific enzymes, such as Cytochrome P450 3A4, in drug-induced liver toxicity, with publications examining sorafenib and lapatinib. Kaufmann has also explored non-invasive screening methods for cancer, including proteomic profiling of tear fluid for colon cancer detection. Additionally, her research has encompassed the development of hydrogel-based wound treatments incorporating antibiotics against resistant pathogens in murine models. Her publication record includes studies on analytical techniques for protein kinetics and the impact of dietary components, like wild blueberries, on inflammatory responses in children. Kaufmann has a cited h-index of 15 across 37 publications.
Metrics
- h-index: 15
- Publications: 38
- Citations: 600
Positions
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Staff Scientist 2021–presentUniversity of Arkansas for Medical Sciences Pediatrics ORCID
Selected Publications
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A Comparison of Derivatives of Alanine and d -Alanine Used in Gas Chromatography–Mass Spectrometry Analysis for Protein Kinetics (2025)
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The Role of Cytochrome P450 3A4-Mediated Metabolism in Sorafenib and Lapatinib Hepatotoxicity (2023)
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Wild-Blueberry Volatile and Phenolic Fractions Mitigate LPS-Induced Inflammatory Responses in Whole Blood of Children (2022)
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Proteomic profiling of tear fluid as a promising non-invasive screening test for colon cancer (2022)
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Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection (2021)
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Paenipeptin Analogues Potentiate Clarithromycin and Rifampin against mcr-1 -Mediated Polymyxin-Resistant Escherichia coli In Vivo (2020)
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Dantrolene Attenuates Cardiotoxicity of Doxorubicin Without Reducing its Antitumor Efficacy in a Breast Cancer Model (2020)
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Reducing doxorubicin cardiotoxicity in rats with mammary tumors by dantrolene. (2017)
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Immunotargeted Photodynamic Therapy for Cholesteatoma (2014)
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Increased efficacy and reduced cardiotoxicity of metronomic treatment with cyclophosphamide in rat breast cancer. (2011)
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Conductive interstitial thermal therapy (CITT) inhibits recurrence and metastasis in rabbit VX2 carcinoma model (2009)
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Dead or alive? Autofluorescence distinguishes heat-fixed from viable cells (2009)
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Inhibition of gut glutathione transport by a breast cancer carcinogen (2004)
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Timing of oral glutamine on DMBA-induced tumorigenesis (2003)
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Glutamine supplementation reduces glutathione levels and stimulates apoptosis in DMBA-induced mammary tumors (2003)
Collaboration Network
Top Collaborators
- Dantrolene Attenuates Cardiotoxicity of Doxorubicin Without Reducing its Antitumor Efficacy in a Breast Cancer Model
- Gut glutathione metabolism and changes with 7,12-DMBA and glutamine
- Increased efficacy and reduced cardiotoxicity of metronomic treatment with cyclophosphamide in rat breast cancer.
- Glutamine supplementation reduces glutathione levels and stimulates apoptosis in DMBA-induced mammary tumors
- Timing of oral glutamine on DMBA-induced tumorigenesis
Showing 5 of 7 shared publications
- Dead or alive? Autofluorescence distinguishes heat-fixed from viable cells
- Dantrolene Attenuates Cardiotoxicity of Doxorubicin Without Reducing its Antitumor Efficacy in a Breast Cancer Model
- Proteomic profiling of tear fluid as a promising non-invasive screening test for colon cancer
- Conductive interstitial thermal therapy (CITT) inhibits recurrence and metastasis in rabbit VX2 carcinoma model
- Reducing doxorubicin cardiotoxicity in rats with mammary tumors by dantrolene.
- Gut glutathione metabolism and changes with 7,12-DMBA and glutamine
- Glutamine supplementation reduces glutathione levels and stimulates apoptosis in DMBA-induced mammary tumors
- Timing of oral glutamine on DMBA-induced tumorigenesis
- Inhibition of gut glutathione transport by a breast cancer carcinogen
- Gut glutathione metabolism and changes with 7,12-DMBA and glutamine
- Timing of oral glutamine on DMBA-induced tumorigenesis
- Inhibition of gut glutathione transport by a breast cancer carcinogen
- Dantrolene Attenuates Cardiotoxicity of Doxorubicin Without Reducing its Antitumor Efficacy in a Breast Cancer Model
- Increased efficacy and reduced cardiotoxicity of metronomic treatment with cyclophosphamide in rat breast cancer.
- Reducing doxorubicin cardiotoxicity in rats with mammary tumors by dantrolene.
- Dead or alive? Autofluorescence distinguishes heat-fixed from viable cells
- Conductive interstitial thermal therapy (CITT) inhibits recurrence and metastasis in rabbit VX2 carcinoma model
- Dead or alive? Autofluorescence distinguishes heat-fixed from viable cells
- Conductive interstitial thermal therapy (CITT) inhibits recurrence and metastasis in rabbit VX2 carcinoma model
- Dead or alive? Autofluorescence distinguishes heat-fixed from viable cells
- Conductive interstitial thermal therapy (CITT) inhibits recurrence and metastasis in rabbit VX2 carcinoma model
- Dead or alive? Autofluorescence distinguishes heat-fixed from viable cells
- Conductive interstitial thermal therapy (CITT) inhibits recurrence and metastasis in rabbit VX2 carcinoma model
- Proteomic profiling of tear fluid as a promising non-invasive screening test for colon cancer
- Effect of Glutamine on Radiation Morbidity in Breast Conservation Therapy
- Glutamine supplementation reduces glutathione levels and stimulates apoptosis in DMBA-induced mammary tumors
- Inhibition of gut glutathione transport by a breast cancer carcinogen
- Gut glutathione metabolism and changes with 7,12-DMBA and glutamine
- Inhibition of gut glutathione transport by a breast cancer carcinogen
- Reducing doxorubicin cardiotoxicity in rats with mammary tumors by dantrolene.
- Inhibition of gut glutathione transport by a breast cancer carcinogen
- Gut glutathione metabolism and changes with 7,12-DMBA and glutamine
- Timing of oral glutamine on DMBA-induced tumorigenesis
- Immunotargeted Photodynamic Therapy for Cholesteatoma
- Conductive interstitial thermal therapy (CITT) inhibits recurrence and metastasis in rabbit VX2 carcinoma model
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