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Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
S
Srinivas Jayanthi
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Also affiliated: Osmania University (2009)
13 h-index
43 pubs
730 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Srinivas Jayanthi's research investigates molecular mechanisms underlying biological processes, with a focus on protein interactions and their implications in disease. He has studied the molecular insights into cytochrome c and nucleotide regulation of apoptosome function, relevant to cancer. Jayanthi's work also includes examining the molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity and novel molecular interactions of acylcarnitines and fatty acids with myoglobin. His research has explored oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agents and the role of indoleamine 2,3-dioxygenase in diabetic cataract pathogenesis in rats. Jayanthi has also contributed to studies on controlling chitosan-based encapsulation for drug delivery and the biochemical pathways in plant phytoalexin diversification. His scholarly output includes 45 publications with 729 citations and an h-index of 13. He has collaborated with researchers from the University of Arkansas at Fayetteville and the University of Arkansas at Monticello.
Metrics
- h-index: 13
- Publications: 43
- Citations: 730
Selected Publications
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Charge reversal in the heparin-binding pocket enhances the stability and activity of the human FGF1 (2026)
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Simplification of the purification of heat stable recombinant low molecular weight proteins and peptides from GST-fusion products (2021)
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Engineered FGF compositions and methods of use thereof (2019)Journal of the Arkansas Academy of Science OpenAlex
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Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer (2019)
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Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity (2019)
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Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity (2019)
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Probing the role of proline −135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor (2018)
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Identification of avian vasotocin receptor subtype-specific antagonists involved in the stress response of the chicken,Gallus gallus (2018)
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Effect of extension of the heparin binding pocket on the structure, stability, and cell proliferation activity of the human acidic fibroblast growth factor (2017)
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Stilbenoid prenyltransferases define key steps in the diversification of peanut phytoalexins (2017)
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Simple and Efficient Purification of Recombinant Proteins Using the Heparin‐Binding Affinity Tag (2017)
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Backbone and side-chain 1H, 15N, and 13C resonance assignments of a novel Staphylococcal inhibitor of myeloperoxidase (2017)
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Modulation of Interleukin-12 activity in the presence of heparin (2017)
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Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin (2016)
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Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle (2016)
Collaboration Network
Top Collaborators
Thallapuranam Krishnaswamy Suresh Kumar
University of Arkansas at Fayetteville
34 shared publications
In database
- Controlling chitosan-based encapsulation for protein and vaccine delivery
- Oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agents
- Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer
- Modulation of Interleukin-12 activity in the presence of heparin
- Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin
Showing 5 of 34 shared publications
David A. Zaharoff
North Carolina State University (US)
10 shared publications
- Controlling chitosan-based encapsulation for protein and vaccine delivery
- Modulation of Interleukin-12 activity in the presence of heparin
- Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity
- Efficient production and purification of recombinant human interleukin-12 (IL-12) overexpressed in mammalian cells without affinity tag
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
Showing 5 of 10 shared publications
Bhanu Koppolu
8 shared publications
- Controlling chitosan-based encapsulation for protein and vaccine delivery
- Modulation of Interleukin-12 activity in the presence of heparin
- Efficient production and purification of recombinant human interleukin-12 (IL-12) overexpressed in mammalian cells without affinity tag
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
- Effect of extension of the heparin binding pocket on the structure, stability, and cell proliferation activity of the human acidic fibroblast growth factor
Showing 5 of 8 shared publications
Ralph Henry
University of Arkansas at Fayetteville (US)
7 shared publications
- Regulation of Structural Dynamics within a Signal Recognition Particle Promotes Binding of Protein Targeting Substrates
- Heparin-binding peptide as a novel affinity tag for purification of recombinant proteins
- Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle
- Role of Structural Flexibility of cpSRP43 in Binding Substrates during Post-Translational Targeting
- Three-Dimensional Structure of the 54-Kda Subunit of the Chloroplast Signal Recognition Particle using Molecular Modeling
Showing 5 of 7 shared publications
Rory Henderson
University of Arkansas at Fayetteville (US)
6 shared publications
- Regulation of Structural Dynamics within a Signal Recognition Particle Promotes Binding of Protein Targeting Substrates
- Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle
- Acquisition of Multidimensional NMR Data on GST-Fused Proteins
- Role of Structural Flexibility of cpSRP43 in Binding Substrates during Post-Translational Targeting
- Three-Dimensional Structure of the 54-Kda Subunit of the Chloroplast Signal Recognition Particle using Molecular Modeling
Showing 5 of 6 shared publications
Robyn L. Goforth
University of Arkansas at Fayetteville (US)
6 shared publications
- Regulation of Structural Dynamics within a Signal Recognition Particle Promotes Binding of Protein Targeting Substrates
- Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle
- Role of Structural Flexibility of cpSRP43 in Binding Substrates during Post-Translational Targeting
- Three-Dimensional Structure of the 54-Kda Subunit of the Chloroplast Signal Recognition Particle using Molecular Modeling
- Investigation of the Structural Stability of cpSRP43 Chromodomain2 by Hydrogen-Deuterium Exchange
Showing 5 of 6 shared publications
Ravi Kumar Gundampati
University of Arkansas at Fayetteville
6 shared publications
In database
- Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer
- Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
- Effect of extension of the heparin binding pocket on the structure, stability, and cell proliferation activity of the human acidic fibroblast growth factor
- Probing the role of proline −135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor
Showing 5 of 6 shared publications
Alicia Kight
University of Arkansas at Fayetteville
5 shared publications
In database
- Regulation of Structural Dynamics within a Signal Recognition Particle Promotes Binding of Protein Targeting Substrates
- Heparin-binding peptide as a novel affinity tag for purification of recombinant proteins
- Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle
- Role of Structural Flexibility of cpSRP43 in Binding Substrates during Post-Translational Targeting
- Investigation of the Structural Stability of cpSRP43 Chromodomain2 by Hydrogen-Deuterium Exchange
Sean G. Smith
North Carolina State University (US)
4 shared publications
- Controlling chitosan-based encapsulation for protein and vaccine delivery
- Modulation of Interleukin-12 activity in the presence of heparin
- Efficient production and purification of recombinant human interleukin-12 (IL-12) overexpressed in mammalian cells without affinity tag
- Corrigendum to ‘Controlling chitosan-based encapsulation for protein and vaccine delivery’ [Biomaterials 35 (2014) 4382–4389]
David S. McNabb
University of Arkansas at Fayetteville
4 shared publications
In database
- Heparin-binding peptide as a novel affinity tag for purification of recombinant proteins
- Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity
- Production of an anti‐Candida peptide via fed batch and ion exchange chromatography
- Engineered FGF compositions and methods of use thereof
Igor Prudovsky
Maine Medical Center Research Institute (US)
3 shared publications
- Folding of Fibroblast Growth Factor 1 Is Critical for Its Nonclassical Release
- Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factor
- Molecular Cloning and Overexpression of WAP Domain of Anosmin-1 (a-WAP) in Escherichia coli
Feng Gao
University of Arkansas at Fayetteville
3 shared publications
In database
- Regulation of Structural Dynamics within a Signal Recognition Particle Promotes Binding of Protein Targeting Substrates
- Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle
- Role of Structural Flexibility of cpSRP43 in Binding Substrates during Post-Translational Targeting
Colin D. Heyes
University of Arkansas at Fayetteville
3 shared publications
In database
- Regulation of Structural Dynamics within a Signal Recognition Particle Promotes Binding of Protein Targeting Substrates
- Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle
- Role of Structural Flexibility of cpSRP43 in Binding Substrates during Post-Translational Targeting
Barbara K. Felber
National Institutes of Health (US)
3 shared publications
- Modulation of Interleukin-12 activity in the presence of heparin
- Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity
- Efficient production and purification of recombinant human interleukin-12 (IL-12) overexpressed in mammalian cells without affinity tag
Jordan O’Malley
Roswell Park Comprehensive Cancer Center (US)
3 shared publications
- Oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agents
- Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer
- Abstract 3058: Oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agents
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