Thallapuranam Krishnaswamy Suresh Kumar
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Assistant Professor
Also affiliated: Brigham Young University (2019); National Institute of Technology Kurukshetra (2021–2022); Amrita Institute of Medical Sciences and Research Centre (2007); Novartis (Switzerland) (1998); National Institutes of Health (2024); M.J.P. Rohilkhand University (2017); University of Miami (2007); National Taiwan Ocean University (2005); University of Leicester (1998); Christian Medical College, Vellore (2004); Kurukshetra University (2017–2022); Centre for Cellular and Molecular Biology (1992–1995); Florida International University (2007); National Academies of Sciences, Engineering, and Medicine (2005); Touro College (2021); Hong Kong University of Science and Technology (2002); National Tsing Hua University (1995–2007); University of Missouri Health System (1996); National Institute of Food Technology Entrepreneurship and Management (2025); Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya (2020); National Institute of Health and Family Welfare (2025); Lok Nayak Jai Prakash Narayan Hospital (2011); Acharya Narendra Deva University of Agriculture and Technology (2023); Sardar Vallabhbhai Patel University of Agriculture & Technology (2023); Advanced Systems Laboratory (2011); Institute of Life Sciences (2011); Regional Urology (2019); National Cancer Institute (2024); Biotechnology Research Institute (2005); OmniActive Health Technologies (India) (2010); Maine Medical Center Research Institute (2005–2007); Ministry of Health and Family Welfare (2025); Center for Cancer Research (2024); Hindu College of Pharmacy (2021); The Ohio State University (2001–2002); Covance (United States) (2010); Friedrich Schiller University Jena (2023); University of Hong Kong (2002); Osmania University (1988–1990); Sri Sivasubramaniya Nadar College of Engineering (2025); Indian Institute of Technology Kanpur (1979)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Thallapuranam Krishnaswamy Suresh Kumar's research focuses on understanding protein structure, folding, and binding interactions, with a particular emphasis on fibroblast growth factors (FGFs) and their role in biological functions and disease. He is the Principal Investigator on a $435,226 NIH/National Institute of General Medical Sciences grant to develop hyperstable FGF1-FGF2 based therapeutic formulations for wound care. His work also explores the broader implications of FGF signaling in various physiological processes and disease states, as evidenced by his publications on endocrine FGFs and FGF/FGFR signaling.
Kumar also investigates other areas of biological science, including the role of gut bacteria and diet in health, and the mechanisms underlying amyloidogenesis. His research interests extend to drug delivery systems, with a publication on nanostructured lipid carriers, and a review of rattlesnake venoms. He maintains an active research group at the University of Arkansas at Fayetteville and has a significant publication record, indicated by his h-index of 31 and over 239 total publications. His collaborations include work with Vivek Govind Kumar, Shilpi Agrawal, Mahmoud Moradi, and Mercede Furr, all from the University of Arkansas at Fayetteville.
Metrics
- h-index: 31
- Publications: 240
- Citations: 3,579
Selected Publications
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Harnessing Affinity Tags for Recombinant Protein Purification: Concepts, Methods, and Troubleshooting (2026)
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One-step purification of a bioactive PAK1-derived peptide (2025)
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Signaling of Mitogenic and Metabolic Activities by Fibroblast Growth Factors (2025)
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Pathology and Therapeutic Significance of Fibroblast Growth Factors (2025)
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Decoding FGF/FGFR Signaling: Insights into Biological Functions and Disease Relevance (2024)
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Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant? (2024)
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Overexpression and Purification of Mitogenic and Metabolic Fibroblast Growth Factors (2024)
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A Review of Rattlesnake Venoms (2023)
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Foreword I (2023)
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cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach (2023)
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A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products (2023)
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Binding affinity estimation from restrained umbrella sampling simulations (2022)
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Amyloidogenesis: What Do We Know So Far? (2022)
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Binding Affinity Estimation from Restrained Umbrella Sampling Simulations (2022)
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Design and characterization of a FGF1‐FGF21 chimeric protein with increased stability and enhanced antidiabetic activities (2022)
Federal Grants 1 $435,226 total
Hyperstable FGF1-FGF2 based therapeutic formulation for wound care
Collaboration Network
Top Collaborators
- The Saga of Endocrine FGFs
- Binding affinity estimation from restrained umbrella sampling simulations
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Binding Affinity Estimation from Restrained Umbrella Sampling Simulations
Showing 5 of 9 shared publications
- Binding affinity estimation from restrained umbrella sampling simulations
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Binding Affinity Estimation from Restrained Umbrella Sampling Simulations
Showing 5 of 9 shared publications
- Binding affinity estimation from restrained umbrella sampling simulations
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Binding Affinity Estimation from Restrained Umbrella Sampling Simulations
Showing 5 of 8 shared publications
- The Saga of Endocrine FGFs
- Decoding FGF/FGFR Signaling: Insights into Biological Functions and Disease Relevance
- Amyloidogenesis: What Do We Know So Far?
- Stability Comparisons between Natural versus Engineered Archaeal Heat-Shock Proteins
- Stability Comparisons between Natural versus Engineered Archaeal Heat‐Shock Proteins
Showing 5 of 7 shared publications
- Simplification of the purification of heat stable recombinant low molecular weight proteins and peptides from GST-fusion products
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Overexpression and Purification of Mitogenic and Metabolic Fibroblast Growth Factors
- A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products
- Signaling of Mitogenic and Metabolic Activities by Fibroblast Growth Factors
Showing 5 of 6 shared publications
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach
- Stability Comparisons between Natural versus Engineered Archaeal Heat-Shock Proteins
- Stability Comparisons between Natural versus Engineered Archaeal Heat‐Shock Proteins
- cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach
Showing 5 of 6 shared publications
- The Saga of Endocrine FGFs
- A Review of Rattlesnake Venoms
- Overexpression and Purification of Mitogenic and Metabolic Fibroblast Growth Factors
- Design and characterization of a FGF1‐FGF21 chimeric protein with increased stability and enhanced antidiabetic activities
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach
- Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent Dyes in the flexible N-Terminal region and a rigid β-turn region
- cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach
- Simplification of the purification of heat stable recombinant low molecular weight proteins and peptides from GST-fusion products
- A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products
- One-step purification of a bioactive PAK1-derived peptide
- Stability Comparisons between Natural versus Engineered Archaeal Heat-Shock Proteins
- Stability Comparisons between Natural versus Engineered Archaeal Heat‐Shock Proteins
- Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant?
- Stability Comparisons between Natural versus Engineered Archaeal Heat-Shock Proteins
- Stability Comparisons between Natural versus Engineered Archaeal Heat‐Shock Proteins
- Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant?
- Decoding FGF/FGFR Signaling: Insights into Biological Functions and Disease Relevance
- Pathology and Therapeutic Significance of Fibroblast Growth Factors
- Characterization of the Structure, Stability, Bioactivity of Recombinant FGF19
- Decoding FGF/FGFR Signaling: Insights into Biological Functions and Disease Relevance
- Pathology and Therapeutic Significance of Fibroblast Growth Factors
- Overexpression and Purification of Mitogenic and Metabolic Fibroblast Growth Factors
- Simplification of the purification of heat stable recombinant low molecular weight proteins and peptides from GST-fusion products
- A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products
- Simplification of the purification of heat stable recombinant low molecular weight proteins and peptides from GST-fusion products
- A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products
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