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Dr. Suman Kumar Samanta's research focuses on the molecular pharmacology of cancer, the study of tumor biology, and the investigation of therapeutic potential found in indigenous medicinal plants. His work integrates traditional knowledge with contemporary scientific methods to explore novel solutions for cancer treatment. This research has led to over 40 publications in journals such as the *Journal of the National Cancer Institute*, *Cancer Letters*, and *Pharmacological Research*, and includes one international and two national patents.
Dr. Samanta's recent publications examine the pharmacological effects of various plant-derived compounds, including kaempferol 3-O-rutinoside, isoverbascoside, astragalin, and mahanine, on cellular processes relevant to cancer and metabolic disorders. He has investigated mechanisms such as SIRT1 induction, GLUT4 translocation, inhibition of estrogen receptor-α and CDK4/6 expression, and modulation of adipogenesis. His work also includes comprehensive analyses of dietary phytochemicals as protective agents against breast cancer and studies on the effects of certain chemical compounds on fertility and metabolic dysfunction.
Prior to his current role, Dr. Samanta completed post-doctoral studies at the University of Pittsburgh and held a position as Scientist C at the Institute of Advanced Study in Science and Technology (IASST) in India. His research network includes collaborations with researchers at the University of Arkansas for Medical Sciences, such as Mumtaz Patel, Mausam Patel, Gary D. Lewis, and R.J. Megahed, with whom he has co-authored multiple publications. Dr. Samanta maintains an active lab website to share his research findings.
Metrics
- h-index: 18
- Publications: 47
- Citations: 954
Selected Publications
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Dual-Energy Spectral CT Quantitative Parameters as Potential Indicator of Response Assessment in Head-Neck Cancer Treatment: A Preliminary Study (2025)
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A Single Institution Experience of a Biweekly Head and Neck Contouring Peer Review (2023)
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Analysis of the Cancer Imaging Archive for Patterns of Locoregional Failure in Relation to the Mucous Membranes among Patients with Head and Neck Squamous Cell Carcinoma: Potential Organ at Risk that can be Spared? (2023)
Collaboration Network
Top Collaborators
Narayan Chandra Talukdar
Assam Down Town University (IN)
8 shared publications
- Kaempferol 3-O-rutinoside from Antidesma acidum Retz. Stimulates glucose uptake through SIRT1 induction followed by GLUT4 translocation in skeletal muscle L6 cells
- Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade
- Astragalin mediates the pharmacological effects of <i>Lysimachia candida</i> Lindl on adipogenesis via downregulating <scp>PPARG</scp> and <scp>FKBP51</scp> signaling cascade
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Effect of multiple doses of N-methyl-N-nitrosourea, an end product of methylguanidine (found in processed food), on the fertility of female Swiss albino mice
Showing 5 of 8 shared publications
Raghuram Kandimalla
University of Louisville (US)
6 shared publications
- Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade
- Astragalin mediates the pharmacological effects of <i>Lysimachia candida</i> Lindl on adipogenesis via downregulating <scp>PPARG</scp> and <scp>FKBP51</scp> signaling cascade
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Effect of multiple doses of N-methyl-N-nitrosourea, an end product of methylguanidine (found in processed food), on the fertility of female Swiss albino mice
- Oncogene Downregulation by Mahanine Suppresses Drug-Sensitive and Drug-Resistant Lung Cancer and Inhibits Orthotopic Tumor Progression
Showing 5 of 6 shared publications
Rajlakshmi Devi
Institute of Advanced Study in Science and Technology (IN)
5 shared publications
- Pharmacologically active chemical composite of<i>Musa balbisiana</i>ameliorates oxidative stress, mitochondrial cellular respiration, and thereby metabolic dysfunction
- Dietary phytochemicals/nutrients as promising protector of breast cancer development: a comprehensive analysis
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Effect of multiple doses of N-methyl-N-nitrosourea, an end product of methylguanidine (found in processed food), on the fertility of female Swiss albino mice
- Chemical composite of indigenous whole grain scented joha rice varietal prevents type 2 diabetes in rats through ameliorating insulin sensitization by the IRS-1/AKT/PI3K signalling cascade
Paramita Choudhury
Institute of Advanced Study in Science and Technology (IN)
4 shared publications
- Dietary phytochemicals/nutrients as promising protector of breast cancer development: a comprehensive analysis
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Effect of multiple doses of N-methyl-N-nitrosourea, an end product of methylguanidine (found in processed food), on the fertility of female Swiss albino mice
- Chemical composite of indigenous whole grain scented joha rice varietal prevents type 2 diabetes in rats through ameliorating insulin sensitization by the IRS-1/AKT/PI3K signalling cascade
Bhaskarjyoti Gogoi
Global University (LB)
4 shared publications
- Dietary phytochemicals/nutrients as promising protector of breast cancer development: a comprehensive analysis
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Editorial: Phytochemicals in cancer prevention and therapeutics: Current advancement and future perspective
- Exopolysaccharides of Potential Probiotic Bacteria <i>Bacillus subtilis</i> BB2: Characterization, Antioxidant and Antibiofilm Activities
Bhaswati Kashyap
Cotton University (IN)
3 shared publications
- Kaempferol 3-O-rutinoside from Antidesma acidum Retz. Stimulates glucose uptake through SIRT1 induction followed by GLUT4 translocation in skeletal muscle L6 cells
- Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade
- Astragalin mediates the pharmacological effects of <i>Lysimachia candida</i> Lindl on adipogenesis via downregulating <scp>PPARG</scp> and <scp>FKBP51</scp> signaling cascade
Jagat C. Borah
Institute of Advanced Study in Science and Technology (IN)
3 shared publications
- Kaempferol 3-O-rutinoside from Antidesma acidum Retz. Stimulates glucose uptake through SIRT1 induction followed by GLUT4 translocation in skeletal muscle L6 cells
- Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade
- Astragalin mediates the pharmacological effects of <i>Lysimachia candida</i> Lindl on adipogenesis via downregulating <scp>PPARG</scp> and <scp>FKBP51</scp> signaling cascade
Partha Pratim Sarma
Institute of Advanced Study in Science and Technology (IN)
3 shared publications
- Pharmacologically active chemical composite of<i>Musa balbisiana</i>ameliorates oxidative stress, mitochondrial cellular respiration, and thereby metabolic dysfunction
- Dietary phytochemicals/nutrients as promising protector of breast cancer development: a comprehensive analysis
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
Farrukh Aqil
University of Louisville (US)
3 shared publications
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Oncogene Downregulation by Mahanine Suppresses Drug-Sensitive and Drug-Resistant Lung Cancer and Inhibits Orthotopic Tumor Progression
- Abstract 707: Mahanine, a carbazole alkaloid attenuates lung cancer progression
Disha N. Moholkar
University of Louisville (US)
3 shared publications
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Oncogene Downregulation by Mahanine Suppresses Drug-Sensitive and Drug-Resistant Lung Cancer and Inhibits Orthotopic Tumor Progression
- Abstract 707: Mahanine, a carbazole alkaloid attenuates lung cancer progression
Ramesh C. Gupta
University of Louisville (US)
3 shared publications
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Oncogene Downregulation by Mahanine Suppresses Drug-Sensitive and Drug-Resistant Lung Cancer and Inhibits Orthotopic Tumor Progression
- Abstract 707: Mahanine, a carbazole alkaloid attenuates lung cancer progression
Momita Das
Institute of Advanced Study in Science and Technology (IN)
2 shared publications
- Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
- Effect of multiple doses of N-methyl-N-nitrosourea, an end product of methylguanidine (found in processed food), on the fertility of female Swiss albino mice
Swarnali Bhattacharjee
Gauhati University (IN)
2 shared publications
- Effect of multiple doses of N-methyl-N-nitrosourea, an end product of methylguanidine (found in processed food), on the fertility of female Swiss albino mice
- Chemical composite of indigenous whole grain scented joha rice varietal prevents type 2 diabetes in rats through ameliorating insulin sensitization by the IRS-1/AKT/PI3K signalling cascade
Sagar Barge
Cotton University (IN)
2 shared publications
- Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade
- Astragalin mediates the pharmacological effects of <i>Lysimachia candida</i> Lindl on adipogenesis via downregulating <scp>PPARG</scp> and <scp>FKBP51</scp> signaling cascade
Simanta Bharadwaj
Institute of Advanced Study in Science and Technology (IN)
2 shared publications
- Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade
- Astragalin mediates the pharmacological effects of <i>Lysimachia candida</i> Lindl on adipogenesis via downregulating <scp>PPARG</scp> and <scp>FKBP51</scp> signaling cascade
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