Match tier Likely match
Presence Formerly Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-16

Bill J. Gurley

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Principal Scientist

Formerly Arkansas Affiliated with Arkansas State University, NCTR, University of Arkansas, UAMS through 2024; recent publications list United States Pharmacopeial Convention, University of Mississippi.

Faculty Researcher

35 h-index 171 pubs 5,913 cited

  • Humans
  • Dietary Supplements
  • Herb-Drug Interactions
  • Male
  • Plant Extracts
  • Female
  • Animals
  • Adult
  • Plant Preparations
  • Chromatography, High Pressure Liquid
  • Chemical and Drug Induced Liver Injury
  • Cytochrome P-450 Enzyme System
  • Drug Interactions
  • Cytochrome P-450 CYP3A
  • Cannabis

Biography and Research Information

OverviewAI-generated summary

Bill J. Gurley's research focuses on the complex interactions between dietary supplements, herbal products, and pharmaceutical drugs, particularly concerning their impact on human health and drug metabolism. He investigates how plant extracts and their constituents can modulate the activity of key drug-metabolizing enzymes, transporters, and nuclear receptors, which are critical for the safe and effective use of medications. His work also addresses the potential for hepatotoxicity arising from herbal dietary supplements and explores analytical challenges in ensuring the quality and safety of these products.

Gurley has published extensively on these topics, with recent work examining the modulatory effects of specific botanicals like Bulbine natalensis and Zingiber officinale on drug metabolism pathways. He also explores the broader landscape of herb-drug interactions for commonly used botanicals on the US market. His research network includes collaborators such as Igor Koturbash, Mitchell R. McGill, Charles M. Quick, and Eric U. Yee, all at the University of Arkansas for Medical Sciences, with whom he has co-authored multiple publications. Gurley's scholarship is evidenced by an h-index of 35 and over 5,900 citations across 171 publications.

Metrics

  • h-index: 35
  • Publications: 171
  • Citations: 5,913

Selected Publications

  • Phenibut: A drug with one too many “buts” (2024)
    Basic & Clinical Pharmacology & Toxicology 4 citations DOI OpenAlex
  • Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024)
    Drug and Chemical Toxicology 3 citations DOI OpenAlex
  • Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice (2024)
    Food and Chemical Toxicology 2 citations DOI OpenAlex
  • Pharmacokinetics (2023)
    Elsevier eBooks 2 citations DOI OpenAlex
  • Hepatotoxicity due to herbal dietary supplements: Past, present and the future (2022)
    Food and Chemical Toxicology 40 citations DOI OpenAlex
  • Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration (2020)
    International Journal of Molecular Sciences 14 citations DOI OpenAlex
  • Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract (2020)
    Journal of Dietary Supplements 35 citations DOI OpenAlex
  • Effect of Aromatase Inhibition (Exemestane) on Urine Concentration of Osteoprotegerin in Healthy Postmenopausal Women (2019)
    The Journal of Clinical Pharmacology DOI OpenAlex
  • The Potential for Pharmacokinetic Interactions Between Cannabis Products and Conventional Medications (2019)
    Journal of Clinical Psychopharmacology 120 citations DOI OpenAlex
  • Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration (2019)
    Molecules 36 citations DOI OpenAlex
  • Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model (2019)
    Molecules 159 citations DOI OpenAlex
  • Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F1 Mice (2019)
    Nutrients 22 citations DOI OpenAlex
  • Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro™ (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments (2018)
    Food and Chemical Toxicology 11 citations DOI OpenAlex

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Collaboration Network

20 Collaborators 12 Institutions 1 Country

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