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Current · Arkansas
Last published
2021
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
S
Susan A. Kadlubar
High Impact
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Also affiliated: University of Minnesota (2008); University of Helsinki (2014); University of Arkansas Medical Center (2011–2017); University of Alabama at Birmingham (2009)
23 h-index
101 pubs
1,750 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Susan A. Kadlubar's research investigates the molecular mechanisms underlying various cancers, with a particular focus on genetic and metabolic factors. Her work has explored the role of signaling pathways, such as JAK/STAT/SOCS, in colon and rectal cancers, and the influence of microRNAs, like hsa-miR-128-3p, on hepatocellular carcinoma development through their regulation of gene expression. Kadlubar has also studied the association between genetic variants in enzymes like sulfotransferase isoform 1A1 (SULT1A1) and their impact on enzymatic activity and cancer risk.
Her research extends to the examination of how factors like oxidized low-density lipoprotein receptor 1 (OLR1) may link obesity and dyslipidemia to cancer. Additionally, her publications include investigations into the in vitro and in vivo metabolism of drugs such as anastrozole, and the expression of sulfotransferases in the human brain. Kadlubar's scholarship metrics include an h-index of 23, with over 101 publications and 1,744 citations, designating her as a highly cited researcher.
Metrics
- h-index: 23
- Publications: 101
- Citations: 1,750
Selected Publications
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Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State (2021)
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Abstract D097: Association between high mammographic density and environmental chromium and arsenic exposure in a pilot study of women living in rural communities (2020)
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Abstract C049: The association between breast cancer and physical activity levels by race in a prospective cohort study (2020)
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Abstract C062: Racial differences in genome-wide DNA methylation profiles by county poverty levels among women residing in Arkansas (2020)
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Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study (2020)
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Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer (2020)
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Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans (2019)
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Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer (2019)
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Individual- and county-level determinants of high breast cancer incidence rates (2019)
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County poverty levels influence genome-wide DNA methylation profiles in African American and European American women (2019)
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Mobile Mammography Screening as an Opportunity to Increase Access of Rural Women to Breast Cancer Research Studies (2019)
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Development and Evaluation of a Blood Glucose Monitoring YouTube Video for Marshallese Patients Using a Community-Based Participatory Research Approach (2019)
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Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer (2019)
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Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans (2019)
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Germline Genetic Variants in GATA3 and Breast Cancer Treatment Outcomes in SWOG S8897 Trial and the Pathways Study (2019)
Collaboration Network
Top Collaborators
Ishwori Dhakal
University of Arkansas for Medical Sciences (US)
22 shared publications
- Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells
- Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- Potential Role of UGT1A4 Promoter SNPs in Anastrozole Pharmacogenomics
- Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients
Showing 5 of 22 shared publications
Lora J. Rogers
University of Arkansas for Medical Sciences
21 shared publications
In database
- Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells
- A functional SNP in the 3′‐UTR of TAP2 gene interacts with microRNA hsa‐miR‐1270 to suppress the gene expression
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer
Showing 5 of 21 shared publications
Vineetha Koroth Edavana
University of Arkansas for Medical Sciences (US)
16 shared publications
- Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- Potential Role of UGT1A4 Promoter SNPs in Anastrozole Pharmacogenomics
- Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics
- Fulvestrant up regulates UGT1A4 and MRP s through ERα and c-Myb pathways: a possible primary drug disposition mechanism
Showing 5 of 16 shared publications
Suzanne Williams
University of Arkansas for Medical Sciences (US)
15 shared publications
- Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- Potential Role of UGT1A4 Promoter SNPs in Anastrozole Pharmacogenomics
- Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics
- Fulvestrant up regulates UGT1A4 and MRP s through ERα and c-Myb pathways: a possible primary drug disposition mechanism
Showing 5 of 15 shared publications
Rosalind B. Penney
University of Arkansas for Medical Sciences (US)
12 shared publications
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- Potential Role of UGT1A4 Promoter SNPs in Anastrozole Pharmacogenomics
- Fulvestrant up regulates UGT1A4 and MRP s through ERα and c-Myb pathways: a possible primary drug disposition mechanism
- CYP19A1 single nucleotide polymorphism associations with CYP19A1, NFκB1, and IL6 gene expression in human normal colon and normal liver samples
- Lack of correlation between in silico projection of function and quantitative real-time PCR-determined gene expression levels in colon tissue
Showing 5 of 12 shared publications
Baitang Ning
United States Food and Drug Administration
12 shared publications
In database
- Suppression of CYP2C9 by MicroRNA hsa-miR-128-3p in Human Liver Cells and Association with Hepatocellular Carcinoma
- Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity
- A functional SNP in the 3′‐UTR of TAP2 gene interacts with microRNA hsa‐miR‐1270 to suppress the gene expression
- Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells
- 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer
Showing 5 of 12 shared publications
Aiwei Yao‐Borengasser
Pulaski Technical College
11 shared publications
In database
- Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- Potential Role of UGT1A4 Promoter SNPs in Anastrozole Pharmacogenomics
- 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer
- Fulvestrant up regulates UGT1A4 and MRP s through ERα and c-Myb pathways: a possible primary drug disposition mechanism
Showing 5 of 11 shared publications
Fred F. Kadlubar
University of Arkansas for Medical Sciences (US)
11 shared publications
- Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity
- Phenotypic CYP2A6 variation and the risk of pancreatic cancer.
- Enzymatic Basis of Phase I and Phase II Drug Metabolism
- Association between GSTM1 copy number, promoter variants and susceptibility to urinary bladder cancer.
- Abstract 2619: Sulfation of toremifene: Individual variability, isoform specificity, and contribution to toremifene pharmacogenomics
Showing 5 of 11 shared publications
Xinfeng Yu
University of Arkansas for Medical Sciences (US)
10 shared publications
- Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells
- Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics
- Abstract 2619: Sulfation of toremifene: Individual variability, isoform specificity, and contribution to toremifene pharmacogenomics
Showing 5 of 10 shared publications
Gail Runnells
University of Arkansas for Medical Sciences
9 shared publications
In database
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- Mobile Mammography Screening as an Opportunity to Increase Access of Rural Women to Breast Cancer Research Studies
- Challenges in recruiting African-American women for a breast cancer genetics study
- County poverty levels influence genome-wide DNA methylation profiles in African American and European American women
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
Showing 5 of 9 shared publications
Xuemei Zhang
University of Arkansas for Medical Sciences (US)
8 shared publications
- Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells
- Functional Genetic Variants in the 3′-Untranslated Region of Sulfotransferase Isoform 1A1 (SULT1A1) and Their Effect on Enzymatic Activity
- Interaction of Cyclooxygenase‐2 promoter polymorphisms with Helicobacter pylori infection and risk of gastric cancer
- Association between GSTM1 copy number, promoter variants and susceptibility to urinary bladder cancer.
- Differential promoter activities of functional haplotypes in the 5′‐flanking region of humanSulfotransferase 1A1
Showing 5 of 8 shared publications
Ping-Ching Hsu
University of Arkansas for Medical Sciences
8 shared publications
In database
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- County poverty levels influence genome-wide DNA methylation profiles in African American and European American women
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
Showing 5 of 8 shared publications
Eric R. Siegel
University of Arkansas for Medical Sciences
7 shared publications
In database
- Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract 1298: The effect of adipocyte-derived factors on lung cells: Exploring the protective nature of excess weight on lung cancer risk
- Abstract 2825: Germline genetic variants in ANGPT1 & 2 and FGF2 are associated with pathologic complete response to bevacizumab in breast cancer patients
Showing 5 of 7 shared publications
Ronda Henry‐Tillman
University of Arkansas for Medical Sciences
7 shared publications
In database
- Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients
- Validation of a genetic risk score for Arkansas women of color
- Mobile Mammography Screening as an Opportunity to Increase Access of Rural Women to Breast Cancer Research Studies
- Change in Mammography Use Following the Revised Guidelines from the U.S. Preventive Services Task Force
- Abstract B44: Differences in meat consumption patterns between African Americans and Caucasians in Arkansas: Potential contribution to cancer disparities.
Showing 5 of 7 shared publications
Issam Makhoul
University of Arkansas for Medical Sciences
6 shared publications
In database
- Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract 2825: Germline genetic variants in ANGPT1 & 2 and FGF2 are associated with pathologic complete response to bevacizumab in breast cancer patients
- Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
Showing 5 of 6 shared publications
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