Match tier Listed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Noemi Garcia Garcia

Researcher

Unknown Researcher

2 h-index 5 pubs 41 cited

  • Humans
  • Protein Kinase Inhibitors
  • Proto-Oncogene Proteins c-ret
  • Antineoplastic Agents
  • Indoles
  • Receptor, trkA
  • Cell Line, Tumor
  • Adenocarcinoma of Lung
  • Lung Neoplasms
  • Antigens, CD
  • rho GTP-Binding Proteins
  • Integrin alpha Chains
  • Integrin alpha5
  • rho-Associated Kinases
  • Drug Development

Biography and Research Information

OverviewAI-generated summary

Noemi Garcia Garcia's research focuses on the molecular mechanisms underlying cancer, particularly lung and breast cancers. She investigates the role of specific proteins, such as Rnd3 and the RET/TRKA signaling pathway, in cancer cell invasion, migration, and metastasis. Her work involves the development and evaluation of small-molecule inhibitors, including indole derivatives, as potential anti-cancer agents. Garcia Garcia has published on targeting the rearranged during transfection (RET) protein in cancer and has explored the potential of dual RET/TRKA inhibitors. Her recent studies have also examined Rnd3's regulation of lung cancer cell invasion and migration independently of ROCK1 signaling, as well as its effect on the metastatic potential of triple-negative breast cancer.

Metrics

  • h-index: 2
  • Publications: 5
  • Citations: 41

Selected Publications

  • Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulation (2026)
    Life Science Alliance 1 citation DOI OpenAlex
  • Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner (2025)
    Cancer Research DOI OpenAlex
  • Abstract 2649: Defining how Rnd3, a novel regulator of breast cancer invasion, affects the metastatic potential of triple-negative breast cancer (2025)
    Cancer Research DOI OpenAlex
  • Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors (2024)
    Bioorganic & Medicinal Chemistry 3 citations DOI OpenAlex
  • Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development (2021)
    Journal of Medicinal Chemistry 37 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

18 Collaborators 4 Institutions 2 Countries

Top Collaborators

View profile →
View profile →
View profile →
View profile →
View profile →
View profile →

Similar Researchers

Based on overlapping research topics