Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Noemi Garcia Garcia's research focuses on the molecular mechanisms underlying cancer, particularly lung and breast cancers. She investigates the role of specific proteins, such as Rnd3 and the RET/TRKA signaling pathway, in cancer cell invasion, migration, and metastasis. Her work involves the development and evaluation of small-molecule inhibitors, including indole derivatives, as potential anti-cancer agents. Garcia Garcia has published on targeting the rearranged during transfection (RET) protein in cancer and has explored the potential of dual RET/TRKA inhibitors. Her recent studies have also examined Rnd3's regulation of lung cancer cell invasion and migration independently of ROCK1 signaling, as well as its effect on the metastatic potential of triple-negative breast cancer.
Metrics
- h-index: 2
- Publications: 5
- Citations: 41
Selected Publications
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Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulation (2026)
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Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner (2025)
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Abstract 2649: Defining how Rnd3, a novel regulator of breast cancer invasion, affects the metastatic potential of triple-negative breast cancer (2025)
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Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors (2024)
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Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development (2021)
Collaboration Network
Top Collaborators
- Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
- Abstract 2649: Defining how Rnd3, a novel regulator of breast cancer invasion, affects the metastatic potential of triple-negative breast cancer
- Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner
- Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulation
- Abstract 2649: Defining how Rnd3, a novel regulator of breast cancer invasion, affects the metastatic potential of triple-negative breast cancer
- Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner
- Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulation
- Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
- Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
- Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
- Abstract 2649: Defining how Rnd3, a novel regulator of breast cancer invasion, affects the metastatic potential of triple-negative breast cancer
- Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner
- Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development
- Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
- Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors
- Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner
- Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner
- Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulation
- Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulation
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