Thallapuranam Krishnaswamy Suresh Kumar Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI High Impact

Assistant Professor

Last publication 2025 Last refreshed 2026-05-22

faculty

31 h-index 239 pubs 3,504 cited

Biography and Research Information

OverviewAI-generated summary

Thallapuranam Krishnaswamy Suresh Kumar is an Assistant Professor at the University of Arkansas at Fayetteville. His research primarily focuses on understanding the molecular mechanisms underlying protein structure, stability, and function, with a particular emphasis on fibroblast growth factors (FGFs) and their interactions. He has investigated the forces governing the thermal unfolding and stabilization of human acidic fibroblast growth factor (FGF1), including the role of heparin binding in these processes. His work also extends to computational methods, such as restrained umbrella sampling simulations, for estimating binding affinities.

Kumar is the Principal Investigator on a grant from the NIH/National Institute of General Medical Sciences for $435,226, which supports research into hyperstable FGF1-FGF2 based therapeutic formulations for wound care. His research group also explores broader biological questions, including the roles of gut bacteria and diet in health, and the microenvironmental factors influencing cancer states and therapeutic opportunities, as indicated by his recent publications.

With 276 total publications and an h-index of 34, Kumar has a significant publication record. He collaborates with several researchers at the University of Arkansas at Fayetteville, including Vivek Govind Kumar, Shilpi Agrawal, Mahmoud Moradi, and Mercede Furr, with whom he has co-authored multiple publications. His work is recognized by his designation as a highly cited researcher.

Metrics

  • h-index: 31
  • Publications: 239
  • Citations: 3,504

Selected Publications

  • One-step purification of a bioactive PAK1-derived peptide (2025)
  • Signaling of Mitogenic and Metabolic Activities by Fibroblast Growth Factors (2025)
  • Pathology and Therapeutic Significance of Fibroblast Growth Factors (2025)
    4 citations DOI OpenAlex
  • Decoding FGF/FGFR Signaling: Insights into Biological Functions and Disease Relevance (2024)
    31 citations DOI OpenAlex
  • Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant? (2024)
  • Overexpression and Purification of Mitogenic and Metabolic Fibroblast Growth Factors (2024)
    1 citation DOI OpenAlex
  • A Review of Rattlesnake Venoms (2023)
    12 citations DOI OpenAlex
  • Foreword I (2023)
  • cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach (2023)
    2 citations DOI OpenAlex
  • A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products (2023)
  • Binding affinity estimation from restrained umbrella sampling simulations (2022)
    54 citations DOI OpenAlex
  • Amyloidogenesis: What Do We Know So Far? (2022)
    14 citations DOI OpenAlex
  • Binding Affinity Estimation from Restrained Umbrella Sampling Simulations (2022)
    4 citations DOI OpenAlex
  • Design and characterization of a FGF1‐FGF21 chimeric protein with increased stability and enhanced antidiabetic activities (2022)
  • Characterization of the Structure, Stability, Bioactivity of Recombinant FGF19 (2022)

View all publications on OpenAlex →

Federal Grants 1 $435,226 total

NIH/National Institute of General Medical Sciences Contact PI Sep 2024 - Aug 2027

Hyperstable FGF1-FGF2 based therapeutic formulation for wound care

National Institute of General Medical Sciences $435,226 R15

Collaboration Network

221 Collaborators 66 Institutions 15 Countries

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