Biography and Research Information
OverviewAI-generated summary
Tsigereda Weldemichael's research focuses on the intersection of pharmacology and cellular damage, particularly in the context of kidney cells. Recent work has investigated how therapeutic agents, specifically EET-based therapeutics, can mitigate damage associated with sorafenib treatment, a known chemotherapy drug. This research has explored the impact of these therapeutics on glomerular cells and podocytes, which are critical components of the kidney's filtration system. Weldemichael's investigations also extend to the molecular mechanisms underlying cancer, with publications examining potent inhibitors of FLT3-ITD mutations, including those resistant to existing treatments like gilteritinib. This work contributes to the understanding of acute myeloid leukemia and the development of targeted therapies. Collaborations include work with Phuc Tran, Abdul H. Khan, Shobanbabu Bommagani, and Abhishek Mishra at the University of Arkansas for Medical Sciences, with shared publications indicating active research partnerships.
Metrics
- h-index: 3
- Publications: 5
- Citations: 69
Selected Publications
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Renal hemodynamics underlie hepatorenal physiology in bile duct-ligated rats (2026)
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Renoprotective approaches against anthracycline nephrotoxicity (2026)
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EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage (2025)
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Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications (2025)
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CD36-mediated endocytosis of proteolysis-targeting chimeras (2025)
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An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L (2023)
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Delivery of Oligonucleotides: Efficiency with Lipid Conjugation and Clinical Outcome (2022)
Collaboration Network
Top Collaborators
Phuc Tran
University of Arkansas for Medical Sciences
2 shared publications
In database
- Delivery of Oligonucleotides: Efficiency with Lipid Conjugation and Clinical Outcome
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
Hongyu Li
University of Arkansas for Medical Sciences (US)
2 shared publications
- Delivery of Oligonucleotides: Efficiency with Lipid Conjugation and Clinical Outcome
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
Michael Dare Asemoloye
Walter Sisulu University (ZA)
2 shared publications
- Feedforward Loops: Evolutionary Conserved Network Motifs Redesigned for Synthetic Biology Applications
- Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications
Mario Andrea Marchisio
Northeastern University (CN)
2 shared publications
- Feedforward Loops: Evolutionary Conserved Network Motifs Redesigned for Synthetic Biology Applications
- Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications
Zhichao Liu
United States Food and Drug Administration (US)
1 shared publication
- Delivery of Oligonucleotides: Efficiency with Lipid Conjugation and Clinical Outcome
Xiuqi Wang
University of Arkansas for Medical Sciences
1 shared publication
In database
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
Rosa Anna DeFilippis
University of California, San Francisco (US)
1 shared publication
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
Gunaganti Naresh
University of Arkansas for Medical Sciences
1 shared publication
In database
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
Yuet‐Kin Leung
University of Arkansas for Medical Sciences
1 shared publication
In database
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
Neil P. Shah
University of California, San Francisco (US)
1 shared publication
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
A. M. Gbadebo
Bells University of Technology (NG)
1 shared publication
- Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications
Tunde Sheriffdeen Bello
Federal University of Technology Minna (NG)
1 shared publication
- Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications
Olumayowa Mary Olowe
North-West University (ZA)
1 shared publication
- Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications
Akinlolu Olalekan Akanmu
North-West University (ZA)
1 shared publication
- Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications
Marta Elisabetta Eleonora Temporiti
University of Pavia (IT)
1 shared publication
- Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications
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