Match tier Listed
Presence Current · Arkansas
Last published 2024
Sources OpenAlex · ORCID
Refreshed 2026-08-18

Madeline Fulmer

Researcher

Graduate Student Researcher

1 h-index 1 pubs 3 cited

  • Chromones
  • Morpholines
  • Solubility
  • Protein Kinase Inhibitors
  • DNA-Activated Protein Kinase
  • DNA Damage
  • Humans
  • T-Lymphocytes
  • Cell Line, Tumor

Biography and Research Information

OverviewAI-generated summary

Madeline Fulmer's research focuses on the discovery and characterization of potential therapeutic agents, specifically protein kinase inhibitors. Her recent publication details the discovery of DA-143, a novel inhibitor of DNA-PKcs, which demonstrates improved solubility compared to existing compounds like NU7441. This work investigates the potential of small molecules to target DNA-activated protein kinase, an enzyme implicated in DNA damage response and cellular processes within tumor cells and T-lymphocytes. Fulmer collaborates with researchers at the University of Arkansas for Medical Sciences, including Randall R Rainwater, Brendan Frett, Ana Clara P. Azevedo‐Pouly, and Baku Acharya, contributing to a shared publication record.

Metrics

  • h-index: 1
  • Publications: 1
  • Citations: 3

Selected Publications

  • Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441 (2024)
    Scientific Reports 3 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

11 Collaborators 4 Institutions 2 Countries

Top Collaborators

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