William W. Greenfield
Professor
University of Arkansas for Medical Sciences
faculty
Obstetrics & Gynecology, College of Medicine
Research Areas
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Biography and Research Information
OverviewAI-generated summary
Dr. William W. Greenfield's research focuses on cervical intraepithelial neoplasia (CIN) and the development of therapeutic vaccines. He has investigated the immune responses to peptide-based human papillomavirus (HPV) therapeutic vaccines, such as PepCan, in the context of treating CIN 2/3, comparing their efficacy against adjuvant alone. His work also includes evaluating DNA extraction protocols from cytology specimens for studying cervical microbiota and assessing the effectiveness of treatments for CIN 2/3.
Beyond HPV research, Dr. Greenfield contributes to public health initiatives. His publications address the development and assessment of public maternal health dashboards in the United States and the awareness and dissemination strategies for Maternal Mortality Review Committee findings in Arkansas. He has also documented state health department responses to the COVID-19 pandemic, including quarantine and isolation facility protocols.
Dr. Greenfield's clinical interests lie in obstetrics and gynecology, with training in daVinci Robotic Surgery. He is actively involved in professional organizations, serving as the Arkansas Section Chair for the American Congress of Obstetrics and Gynecology. His scholarship metrics include an h-index of 11, 26 total publications, and 405 total citations.
Research Overview
Dr. William Greenfield completed his medical degree at Meharry Medical College in Nashville, Tennessee, completed an internship at Baylor College of Medicine in Houston, Texas, and his residency in Obstetrics and Gynecology at the University of Arkansas for Medical Sciences in Little Rock. Before attending medical school, he received a pharmacy degree from Auburn University. His clinical interests are in obstetrics and gynecology. He is trained in daVinci Robotic Surgery. He has made presentations nationally, regionally and locally on topics in his field. Dr. Greenfield currently serves as the Arkansas Section Chair for the American Congress of Obstetrics and Gynecology, and is a member of several professional organizations including:Arkansas Medical SocietyAmerican Medical AssociationAmerican Society of Colposcopy and Cervical PathologyDr. Greenfield enjoys both his obstetric and gynecologic patients. He likes to help educate his patients and guide them to make informed decisions about their healthcare.
Metrics
- h-index: 11
- Publications: 26
- Citations: 405
Selected Publications
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i> (2025) DOI
- Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus <i>Candida</i> adjuvant alone in treating cervical intraepithelial neoplasia 2/3. (2024) DOI
- Public Maternal Health Dashboards in the United States: Descriptive Assessment (2024) DOI
- Maternal Mortality Review Committee findings: awareness and recommended dissemination strategies in Arkansas (2024) DOI
- A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3). (2023) DOI
- Evaluation of DNA extraction protocols from liquid-based cytology specimens for studying cervical microbiota (2021) DOI
Grants & Funding
- DP24-004, PRC, Core: Health Promotion and Disease Prevention Research Centers NIH Co-Investigator
- Understanding and Enhancing T-Cell Responses to High Risk Human Papillomaviruses-Renewal NIH Co-Investigator
- The Arkansas Perinatal Quality Collaborative Centers for Disease Control & Prevention Co-Principal Investigator
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