Match tier Listed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Jasmine Crane

Researcher

Also affiliated: Middlebury College (2016); University of Arkansas Medical Center (2021); Institute on Aging (2022)

Faculty Researcher

3 h-index 10 pubs 49 cited

  • Humans
  • Male
  • Actins
  • Serum Response Factor
  • Carcinoma, Squamous Cell
  • Head and Neck Neoplasms
  • Neoplasm Recurrence, Local
  • Cancer Vaccines
  • Papillomavirus Infections
  • Papillomavirus Vaccines
  • Animals
  • Convulsants
  • Dose-Response Relationship, Drug
  • Indazoles
  • Indoles

Biography and Research Information

OverviewAI-generated summary

Jasmine Crane's research program investigates the therapeutic potential of peptide-based vaccines and immune responses in the context of human papillomavirus (HPV) infections. Crane has published findings from a randomized, double-blind, placebo-controlled Phase I/II clinical trial evaluating an HPV therapeutic vaccine, PepCan, for reducing head and neck cancer recurrence. Prior work has also explored the efficacy of PepCan and Candida adjuvant in treating cervical intraepithelial neoplasia 2/3 (CIN2/3), examining both clinical outcomes and immune responses in Phase 2 trials.

Beyond therapeutic vaccine development, Crane's work extends to fundamental biological mechanisms. This includes studies on the modulation of mitochondrial functions by Rho/SRF inhibitors and investigations into sirtuin gene isoforms and their differential regulation of mitochondrial function in both mouse and human models. Crane collaborates with several researchers at the University of Arkansas for Medical Sciences, including David W. Ussery, Yong‐Chen Lu, Nadia Darwish, and Teresa Evans, with whom she shares four publications.

Metrics

  • h-index: 3
  • Publications: 10
  • Citations: 49

Selected Publications

  • A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer Recurrence (2026)
    medRxiv DOI OpenAlex
  • A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i> (2025)
    medRxiv 3 citations DOI OpenAlex
  • Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus <i>Candida</i> adjuvant alone in treating cervical intraepithelial neoplasia 2/3. (2024)
    Journal of Clinical Oncology 1 citation DOI OpenAlex
  • A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3). (2023)
    Journal of Clinical Oncology 2 citations DOI OpenAlex
  • Rho/SRF Inhibitor Modulates Mitochondrial Functions (2022)
    International Journal of Molecular Sciences 18 citations DOI OpenAlex
  • Sirtuin gene isoforms and genomic sequences of mouse and humans: Divergence across species (2022)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice (2018)
    Journal of Pharmacology and Experimental Therapeutics 25 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

46 Collaborators 4 Institutions 2 Countries

Top Collaborators

View profile →
View profile →
View profile →
View profile →
View profile →
View profile →
View profile →
View profile →

Similar Researchers

Based on overlapping research topics