X
Xuan Zhuang Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Federal Grant PI
Assistant Professor
faculty
18 h-index
75 pubs
1,290 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Xuan Zhuang's research focuses on the evolutionary mechanisms driving genetic adaptation in fish populations, with a particular emphasis on antifreeze proteins and de novo gene evolution. Zhuang investigates how natural selection influences the propagation of new genes, as seen in the antifreeze glycoprotein genes of codfishes. This work explores the diverse origins of similar antifreeze proteins in unrelated fish lineages, providing insights into protein sequence convergence and the birth of new genes.
Further research by Zhuang examines population genetic structures and the consequences of artificial breeding on natural populations, using yellow croaker as a model. This includes assessing resource status and the effects of long-term stock enhancement. Additionally, Zhuang's work delves into the differentiation and temperature adaptation of fish species based on genome-wide single nucleotide polymorphisms (SNPs).
Beyond fish evolution, Zhuang's federally funded research, supported by two NIH/National Institute of General Medical Sciences grants totaling $695,312, investigates complex traits in Drosophila. These grants focus on dissecting cryptic genetic variation and decoding gene-environment interactions through multi-omics approaches. Zhuang leads a research group and collaborates with researchers at the University of Arkansas at Fayetteville, including Vinita Lamba and N. Rives.
Metrics
- h-index: 18
- Publications: 75
- Citations: 1,290
Selected Publications
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Disruption of <i>Drosophila melanogaster</i> Larval Locomotion Caused by Silver Ions (2026)
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An amino acid polymorphism in the membrane progesterone receptor alpha protein is tied to female sexual maturity in the large yellow croaker (Larimichthys crocea) (2025)
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Identification of Salt Tolerance and Stress Response in US Department of Agriculture Tomato Germplasm at the Seedling Stage (2024)
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Diverse Origins of Near-Identical Antifreeze Proteins in Unrelated Fish Lineages Provide Insights Into Evolutionary Mechanisms of New Gene Birth and Protein Sequence Convergence (2024)
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Assessing the population genetic structure of yellow croaker in China: Insights into the ecological and genetic consequences of artificial breeding on natural populations (2024)
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Diverse origins of near-identical antifreeze proteins in unrelated fish lineages provide insights into evolutionary mechanisms of new gene birth and protein sequence convergence (2024)
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Important Role of the Ihh Signaling Pathway in Initiating Early Cranial Remodeling and Morphological Specialization in Cromileptes altivelis (2023)
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Positive and Relaxed Selective Pressures Have Both Strongly Influenced the Evolution of Cryonotothenioid Fishes during Their Radiation in the Freezing Southern Ocean (2023)
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Differentiation and Temperature Adaptation of Pampus Echinogaster Based on Genome-Wide SNPs (2022)
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Positive and relaxed selective pressures have both strongly influenced the evolution of cryonotothenioid fishes during their radiation in the freezing Southern Ocean (2022)
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Propagation of a De Novo Gene under Natural Selection: Antifreeze Glycoprotein Genes and Their Evolutionary History in Codfishes (2021)
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Resource Status and Effect of Long-Term Stock Enhancement of Large Yellow Croaker in China (2021)
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The Genomic Basis of the Genetic Differentiation and Local Adaptive Evolution of Pampus Echinogaster based on SLAF-seq (2021)
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Correction to: Evolution of chaperome gene expression and regulatory elements in the antarctic notothenioid fishes (2021)
Federal Grants 3 $2,032,319 total
NIH/National Institute of General Medical Sciences
Contact PI
Sep 2025 - Jun 2030
Decoding Gene-Environment Interactions in Complex Traits via Multi-Omics Approaches
NIH/National Institute of General Medical Sciences
Contact PI
Sep 2023 - Aug 2026
Dissecting cryptic genetic variation underlying complex traits in Drosophila
Collaboration Network
Top Collaborators
Shaoxiong Ding
Xiamen University (CN)
4 shared publications
- Resource Status and Effect of Long-Term Stock Enhancement of Large Yellow Croaker in China
- Assessing the population genetic structure of yellow croaker in China: Insights into the ecological and genetic consequences of artificial breeding on natural populations
- Important Role of the Ihh Signaling Pathway in Initiating Early Cranial Remodeling and Morphological Specialization in Cromileptes altivelis
- An amino acid polymorphism in the membrane progesterone receptor alpha protein is tied to female sexual maturity in the large yellow croaker (Larimichthys crocea)
Kevin T. Bilyk
Montclair State University (US)
3 shared publications
- Positive and Relaxed Selective Pressures Have Both Strongly Influenced the Evolution of Cryonotothenioid Fishes during Their Radiation in the Freezing Southern Ocean
- Correction to: Evolution of chaperome gene expression and regulatory elements in the antarctic notothenioid fishes
- Positive and relaxed selective pressures have both strongly influenced the evolution of cryonotothenioid fishes during their radiation in the freezing Southern Ocean
Jigui Yuan
Xiamen University (CN)
3 shared publications
- Resource Status and Effect of Long-Term Stock Enhancement of Large Yellow Croaker in China
- Assessing the population genetic structure of yellow croaker in China: Insights into the ecological and genetic consequences of artificial breeding on natural populations
- An amino acid polymorphism in the membrane progesterone receptor alpha protein is tied to female sexual maturity in the large yellow croaker (Larimichthys crocea)
Lisheng Wu
Xiamen University (CN)
3 shared publications
- Resource Status and Effect of Long-Term Stock Enhancement of Large Yellow Croaker in China
- Assessing the population genetic structure of yellow croaker in China: Insights into the ecological and genetic consequences of artificial breeding on natural populations
- Important Role of the Ihh Signaling Pathway in Initiating Early Cranial Remodeling and Morphological Specialization in Cromileptes altivelis
C.‐H. Christina Cheng
University of Illinois Urbana-Champaign (US)
3 shared publications
- Propagation of a De Novo Gene under Natural Selection: Antifreeze Glycoprotein Genes and Their Evolutionary History in Codfishes
- Diverse Origins of Near-Identical Antifreeze Proteins in Unrelated Fish Lineages Provide Insights Into Evolutionary Mechanisms of New Gene Birth and Protein Sequence Convergence
- Diverse origins of near-identical antifreeze proteins in unrelated fish lineages provide insights into evolutionary mechanisms of new gene birth and protein sequence convergence
Zhenxin Cai
3 shared publications
- Hemangioma of glans penis: A case report
- The Low Expression Of ALDOB Is Associated With Poor Prognosis In Renal Clear Cell Carcinoma
- [NSD1 regulates H3K36me2 in the pathogenesis of non-obstructive azoospermia].
De Chun Li
Fudan University (CN)
3 shared publications
- Prediction of subsolid pulmonary nodule growth rate using radiomics
- Prediction of Subsolid Pulmonary Nodule Growth Rate Using Radiomics
- Additional file 1 of Prediction of subsolid pulmonary nodule growth rate using radiomics
Liang Jin
Fudan University (CN)
3 shared publications
- Prediction of subsolid pulmonary nodule growth rate using radiomics
- Prediction of Subsolid Pulmonary Nodule Growth Rate Using Radiomics
- Additional file 1 of Prediction of subsolid pulmonary nodule growth rate using radiomics
Pan Gao
Fudan University (CN)
3 shared publications
- Prediction of subsolid pulmonary nodule growth rate using radiomics
- Prediction of Subsolid Pulmonary Nodule Growth Rate Using Radiomics
- Additional file 1 of Prediction of subsolid pulmonary nodule growth rate using radiomics
Cheng Li
Fudan University (CN)
3 shared publications
- Prediction of subsolid pulmonary nodule growth rate using radiomics
- Prediction of Subsolid Pulmonary Nodule Growth Rate Using Radiomics
- Additional file 1 of Prediction of subsolid pulmonary nodule growth rate using radiomics
Ming Li
Fudan University (CN)
3 shared publications
- Prediction of subsolid pulmonary nodule growth rate using radiomics
- Prediction of Subsolid Pulmonary Nodule Growth Rate Using Radiomics
- Additional file 1 of Prediction of subsolid pulmonary nodule growth rate using radiomics
Fangrui Lou
Yantai University (CN)
2 shared publications
- Differentiation and Temperature Adaptation of Pampus Echinogaster Based on Genome-Wide SNPs
- The Genomic Basis of the Genetic Differentiation and Local Adaptive Evolution of Pampus Echinogaster based on SLAF-seq
Longshan Lin
Fujian Institute of Oceanography (CN)
2 shared publications
- Differentiation and Temperature Adaptation of Pampus Echinogaster Based on Genome-Wide SNPs
- The Genomic Basis of the Genetic Differentiation and Local Adaptive Evolution of Pampus Echinogaster based on SLAF-seq
Hung‐Du Lin
National Tainan Institute of Nursing (TW)
2 shared publications
- Resource Status and Effect of Long-Term Stock Enhancement of Large Yellow Croaker in China
- Assessing the population genetic structure of yellow croaker in China: Insights into the ecological and genetic consequences of artificial breeding on natural populations
Chiara Papetti
University of Padua (IT)
2 shared publications
- Positive and Relaxed Selective Pressures Have Both Strongly Influenced the Evolution of Cryonotothenioid Fishes during Their Radiation in the Freezing Southern Ocean
- Positive and relaxed selective pressures have both strongly influenced the evolution of cryonotothenioid fishes during their radiation in the freezing Southern Ocean
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