Match tier Confirmed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-20

Xuan Zhuang

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI

Assistant Professor

Also affiliated: Qingdao University (2024–2025); Fujian Medical University (2018–2026); Guangxi University (2008–2017); University of Illinois Urbana-Champaign (2009–2019); Guangxi Medical University (2008); Urbana University (2009); Yunnan University (2020); Xiamen University (2006–2025); Peking University (2016–2023); Fudan University (2023–2025); University of Illinois Chicago (2018); University of Chicago (2018–2020); World Wide Web Consortium (2006); First Affiliated Hospital of Xiamen University (2012–2025); Huadong Hospital (2023–2025); Affiliated Hospital of Qingdao University (2024–2025); First Affiliated Hospital of Fujian Medical University (2018); Experimental Center of Subtropical Forestry (2008); Peking University Third Hospital (2017–2023); Huazhong University of Science and Technology (2024); Goodwin College (2013); Xiamen University of Technology (2018)

Faculty Researcher

18 h-index 79 pubs 1,323 cited

  • Animals
  • Humans
  • Male
  • Evolution, Molecular
  • Phylogeny
  • Fish Proteins
  • Perciformes
  • Fishes
  • Antifreeze Proteins
  • Genome
  • Base Sequence
  • Adult
  • Genetic Predisposition to Disease
  • Azoospermia
  • Female

Biography and Research Information

OverviewAI-generated summary

Xuan Zhuang is an Assistant Professor at the University of Arkansas at Fayetteville, focusing on evolutionary biology and genetics. His research investigates the evolutionary mechanisms behind the development of new genes and protein functions, particularly in fish. Zhuang has received significant federal funding for his work, including three grants totaling over $2 million from the National Institutes of Health (NIH) and the National Science Foundation (NSF). These grants support projects aimed at dissecting genetic variation in complex traits, decoding gene-environment interactions, and exploring the origins and evolutionary trajectories of fish antifreeze proteins.

His scholarly output includes numerous publications, with a notable focus on antifreeze proteins in codfishes and cryonotothenioid fishes, as well as population genetics in large yellow croaker. Zhuang's work also extends to other areas, with publications on the NLRP3 inflammasome in oral squamous cell carcinoma and the antihypertensive and antioxidant capacities of peptides from tilapia skin. His research group collaborates with other scientists at the University of Arkansas, including Vinita Lamba and N. Rives. Zhuang's academic profile is further characterized by an h-index of 18 and over 1,300 citations across his 78 publications.

Metrics

  • h-index: 18
  • Publications: 79
  • Citations: 1,323

Selected Publications

  • A recombinant <i>dilp2GS-rpr</i> donor line for adult-inducible IPC ablation across <i>Drosophila</i> genetic backgrounds (2026)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Gene loss under constant cold reveals “natural knockout” loci in Antarctic notothenioid fishes (2026)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Outbred <i>Drosophila</i> populations reveal diet-dependent genetic effects on development time (2026)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Transposable Elements Facilitate the De Novo Origin of Antifreeze Protein and the Diversification of Its Gene Family in Snailfishes (2026)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Disruption of <i>Drosophila melanogaster</i> Larval Locomotion Caused by Silver Ions (2026)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • An amino acid polymorphism in the membrane progesterone receptor alpha protein is tied to female sexual maturity in the large yellow croaker (Larimichthys crocea) (2025)
    Gene DOI OpenAlex
  • Identification of Salt Tolerance and Stress Response in US Department of Agriculture Tomato Germplasm at the Seedling Stage (2024)
    HortScience 3 citations DOI OpenAlex
  • Diverse Origins of Near-Identical Antifreeze Proteins in Unrelated Fish Lineages Provide Insights Into Evolutionary Mechanisms of New Gene Birth and Protein Sequence Convergence (2024)
    Molecular Biology and Evolution 15 citations DOI OpenAlex
  • Assessing the population genetic structure of yellow croaker in China: Insights into the ecological and genetic consequences of artificial breeding on natural populations (2024)
    Aquaculture 15 citations DOI OpenAlex
  • Diverse origins of near-identical antifreeze proteins in unrelated fish lineages provide insights into evolutionary mechanisms of new gene birth and protein sequence convergence (2024)
    bioRxiv (Cold Spring Harbor Laboratory) 5 citations DOI OpenAlex
  • Important Role of the Ihh Signaling Pathway in Initiating Early Cranial Remodeling and Morphological Specialization in Cromileptes altivelis (2023)
    Animals 3 citations DOI OpenAlex
  • Positive and Relaxed Selective Pressures Have Both Strongly Influenced the Evolution of Cryonotothenioid Fishes during Their Radiation in the Freezing Southern Ocean (2023)
    Genome Biology and Evolution 24 citations DOI OpenAlex
  • Differentiation and Temperature Adaptation of Pampus Echinogaster Based on Genome-Wide SNPs (2022)
    Frontiers in Marine Science 6 citations DOI OpenAlex
  • Positive and relaxed selective pressures have both strongly influenced the evolution of cryonotothenioid fishes during their radiation in the freezing Southern Ocean (2022)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Propagation of a De Novo Gene under Natural Selection: Antifreeze Glycoprotein Genes and Their Evolutionary History in Codfishes (2021)
    Genes 16 citations DOI OpenAlex

View all publications on OpenAlex →

Federal Grants 3 $2,182,143 total

NIH Contact PI Sep 2025 - Jun 2030

Decoding Gene-Environment Interactions in Complex Traits via Multi-Omics Approaches

National Institute of General Medical Sciences $408,810 R35
NIH Contact PI Sep 2023 - Aug 2027

Dissecting cryptic genetic variation underlying complex traits in Drosophila

National Institute of General Medical Sciences $436,326 R15

Collaboration Network

47 Collaborators 17 Institutions 6 Countries

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