Histones

2 researchers across 2 institutions

2 Researchers
2 Institutions
0 Grant PIs
2 High Impact

Research in this area investigates histones, the proteins around which DNA wraps to form chromatin. Studies examine how histone modifications, such as acetylation, methylation, and phosphorylation, influence gene expression and cellular processes. Researchers employ techniques in molecular biology, biochemistry, and genomics to understand the structural dynamics of chromatin and its role in regulating biological functions. This includes exploring how aberrant histone regulation contributes to disease development.

This work has implications for public health in Arkansas by contributing to a deeper understanding of diseases. Research into histone function can inform strategies for developing targeted therapies and diagnostic tools for conditions prevalent in the state. Furthermore, understanding the mechanisms of gene regulation is crucial for advancing biomedical research and supporting the growth of the state's biotechnology sector.

This field connects with epigenetics, DNA methylation, and genomics, as well as pharmacological effects, toxicity studies, and the use of nanoparticles. Investigations also involve animal disease models and carcinogen assessment. This research is conducted at multiple institutions across Arkansas, fostering interdisciplinary collaboration.

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Top Researchers

Name Institution h-index Citations Career Stage Badges
Sean D. Taverna UAMS 30 5,093 Faculty High Impact
Marta Pogribna NCTR 24 4,113 High Impact
Epigenetics And Dna Methylation 2 Pharmacological Effects And Toxicity Studies 1 Nanoparticles: Synthesis And Applications 1 Animal, Disease Models 1 Carcinogens And Genotoxicity Assessment 1 Genomics And Chromatin Dynamics 1 Chromatin 1 Receptor Mechanisms And Signaling 1 Genomics And Phylogenetic Studies 1 Protein Structure And Dynamics 1

Strategic Outlook

Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: MEDIUM

Global trajectory
1,739 works in 2026
-1.8% CAGR 2018–2026
Leadership concentration
6.2% held by global top 5 institutions
Fragmented HHI 27
Arkansas position
Arkansas not in global top 100
No AR institution among the top-100 contributors to this topic over the 2018–2026 window.

Top US institutions in this area

  1. 1 Harvard University 744
  2. 2 The University of Texas MD Anderson Cancer Center 632
  3. 3 National Institutes of Health 600
  4. 4 National Cancer Institute 546
  5. 5 Johns Hopkins University 453
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