Match tier
Listed
Presence
Current · Arkansas
Last published
2024
Sources
OpenAlex · ORCID
Refreshed
2026-10-09
E
En Huang
Federal Grant PI
Associate Professor
Also affiliated: Ghent University (2021); The Ohio State University (2012–2024)
Environmental Health Sciences, College of Public Health
21 h-index
47 pubs
1,042 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
En Huang researches the development of natural antimicrobial compounds to enhance food safety and quality. This work includes discovering and characterizing natural antimicrobial peptides, such as bacteriocins, and lipopeptides using chemical and genetic methods. These agents have potential applications as natural food preservatives, animal feed additives, or novel antibiotics against drug-resistant bacteria.
Huang also investigates the transmission, ecology, and evolution of foodborne pathogens and spoilage microorganisms. This research utilizes genomic, transcriptomic, and metagenomic approaches. Huang's work on cefiderocol resistance in carbapenem-resistant pathogens has been supported by a $1 grant from the NIH/National Institute of Allergy and Infectious Diseases, with Huang serving as PI.
With a career h-index of 18 and 957 citations across 48 publications, Huang actively collaborates with researchers at the University of Arkansas for Medical Sciences, including Sun Hee Moon (7 shared publications) and Se‐Ran Jun (5 shared publications). Huang maintains an active lab website and is a recently active researcher.
Metrics
- h-index: 21
- Publications: 47
- Citations: 1,042
Positions
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Assistant professor 2016–presentUniversity of Arkansas for Medical Sciences Environmental and Occupational Health ORCID
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Associate Professor publications 2016–2024University of Arkansas for Medical Sciences Environmental Health Sciences, College of Public Health Institutional directory
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Postdoctoral Researcher 2013–2016Ohio State University Food Science and Technology ORCID
Selected Publications
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Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce (2024)
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Treatment-emergent cefiderocol resistance in carbapenem-resistant Acinetobacter baumannii is associated with insertion sequence IS Aba36 in the siderophore receptor pirA (2024)
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A Multidrug-Resistant Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacter hormaechei Strain from Mixed Sprouts (2024)
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Thermal Inactivation of Escherichia Phage OSYSP and Host Strain Escherichia coli O157:H7 EDL933: A Comparative Kinetic Analysis (2024)
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Lytic Escherichia phage OSYSP acts additively and synergistically with gaseous ozone against Escherichia coli O157:H7 on spinach leaves (2023)
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Carbapenem resistance in the food supply chain (2023)
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Cefiderocol Resistance in Klebsiella pneumoniae Is Linked to SHV Extended-Spectrum β-Lactamase Activities and Functional Loss of the Outer Membrane Porin OmpK35 (2023)
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Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas (2022)
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Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and β-lactamase activities (2022)
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Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences (2022)
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Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection (2021)
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Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States (2021)
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Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable (2021)
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Applications in food technology: antimicrobial peptides (2021)
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Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing (2020)
Federal Grants 1 $1 total
NIH
Contact PI
Sep 2024 - Sep 2025
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Novel linear lipopeptide paenipeptins sensitize multidrug-resistant Gram-negative pathogens to antibiotics - Continuation Year 2020-2021 NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
- Real-Time High Resolution Method for Genomic Surveillance of ESKAPE pathogens NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
- Platelet-Leukocyte Axis in Patients with Chronic Kidney Disease Dialysis Clinic, Inc. Principal Investigator
- Assessment of antibiotic resistance in fresh vegetables from farm to fork National Institute of Food and Agriculture Principal Investigator
Collaboration Network
Top Collaborators
Sun Hee Moon
University of Arkansas for Medical Sciences
14 shared publications
In database
- Control of Salmonella in chicken meat using a combination of a commercial bacteriophage and plant-based essential oils
- Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing
- Novel Linear Lipopeptide Paenipeptins with Potential for Eradicating Biofilms and Sensitizing Gram-Negative Bacteria to Rifampicin and Clarithromycin
- Cefiderocol Resistance in Klebsiella pneumoniae Is Linked to SHV Extended-Spectrum β-Lactamase Activities and Functional Loss of the Outer Membrane Porin OmpK35
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
Showing 5 of 14 shared publications
Ahmed E. Yousef
The Ohio State University (US)
12 shared publications
- Brevibacillin, a cationic lipopeptide that binds to lipoteichoic acid and subsequently disrupts cytoplasmic membrane of Staphylococcus aureus
- Efficacy of Gaseous Ozone Application during Vacuum Cooling against Escherichia coli O157:H7 on Spinach Leaves as Influenced by Bacterium Population Size
- Factors affecting Alicyclobacillus acidoterrestris growth and guaiacol production and controlling apple juice spoilage by lauric arginate and ϵ-polylysine
- New Paenibacillus strain produces a family of linear and cyclic antimicrobial lipopeptides: cyclization is not essential for their antimicrobial activity
- Genome-Guided Mass Spectrometry Expedited the Discovery of Paraplantaricin TC318, a Lantibiotic Produced by Lactobacillus paraplantarum Strain Isolated From Cheese
Showing 5 of 12 shared publications
Mustafa Yeşil
The Ohio State University (US)
6 shared publications
- Efficacy of Gaseous Ozone Application during Vacuum Cooling against Escherichia coli O157:H7 on Spinach Leaves as Influenced by Bacterium Population Size
- Lytic Escherichia phage OSYSP acts additively and synergistically with gaseous ozone against Escherichia coli O157:H7 on spinach leaves
- Draft Genome Sequence of Brevibacillus laterosporus OSY-I 1 , a Strain That Produces Brevibacillin, Which Combats Drug-Resistant Gram-Positive Bacteria
- Complete Genome Sequence of Escherichia Phage OSYSP
- Thermal Inactivation of Escherichia Phage OSYSP and Host Strain Escherichia coli O157:H7 EDL933: A Comparative Kinetic Analysis
Showing 5 of 6 shared publications
Yang Xu
The Ohio State University (US)
5 shared publications
- Brevibacillin, a cationic lipopeptide that binds to lipoteichoic acid and subsequently disrupts cytoplasmic membrane of Staphylococcus aureus
- New Paenibacillus strain produces a family of linear and cyclic antimicrobial lipopeptides: cyclization is not essential for their antimicrobial activity
- Draft Genome Sequence of Brevibacillus laterosporus OSY-I 1 , a Strain That Produces Brevibacillin, Which Combats Drug-Resistant Gram-Positive Bacteria
- Complete Genome Sequence of Escherichia Phage OSYSP
- Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce
Xu Yang
California State Polytechnic University (US)
5 shared publications
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Carbapenem resistance in the food supply chain
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
- Genome-Guided Mass Spectrometry Expedited the Discovery of Paraplantaricin TC318, a Lantibiotic Produced by Lactobacillus paraplantarum Strain Isolated From Cheese
- A Multidrug-Resistant Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacter hormaechei Strain from Mixed Sprouts
Se‐Ran Jun
University of Arkansas for Medical Sciences
5 shared publications
In database
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Treatment-emergent cefiderocol resistance in carbapenem-resistant Acinetobacter baumannii is associated with insertion sequence IS Aba36 in the siderophore receptor pirA
- Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and β-lactamase activities
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
- Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas
Zulema Udaondo
University of Arkansas for Medical Sciences (US)
4 shared publications
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and β-lactamase activities
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
- Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas
Xinhui Li
University of Wisconsin–La Crosse (US)
4 shared publications
- Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States
- Carbapenem resistance in the food supply chain
- Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable
- A Multidrug-Resistant Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacter hormaechei Strain from Mixed Sprouts
David R. Kasler
The Ohio State University (US)
3 shared publications
- Efficacy of Gaseous Ozone Application during Vacuum Cooling against Escherichia coli O157:H7 on Spinach Leaves as Influenced by Bacterium Population Size
- Lytic Escherichia phage OSYSP acts additively and synergistically with gaseous ozone against Escherichia coli O157:H7 on spinach leaves
- Thermal Inactivation of Escherichia Phage OSYSP and Host Strain Escherichia coli O157:H7 EDL933: A Comparative Kinetic Analysis
Walaa E. Hussein
University of Cincinnati Medical Center (US)
3 shared publications
- Genome-Guided Mass Spectrometry Expedited the Discovery of Paraplantaricin TC318, a Lantibiotic Produced by Lactobacillus paraplantarum Strain Isolated From Cheese
- Draft Genome Sequence of Lactobacillus paraplantarum OSY-TC318, a Producer of the Novel Lantibiotic Paraplantaracin TC318
- Applications in food technology: antimicrobial peptides
İsmet Öztürk
Istanbul Arel University (TR)
2 shared publications
- Genome-Guided Mass Spectrometry Expedited the Discovery of Paraplantaricin TC318, a Lantibiotic Produced by Lactobacillus paraplantarum Strain Isolated From Cheese
- Draft Genome Sequence of Lactobacillus paraplantarum OSY-TC318, a Producer of the Novel Lantibiotic Paraplantaracin TC318
Yihong Kaufmann
University of Arkansas for Medical Sciences
2 shared publications
In database
- Paenipeptin Analogues Potentiate Clarithromycin and Rifampin against mcr-1 -Mediated Polymyxin-Resistant Escherichia coli In Vivo
- Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection
Intawat Nookaew
University of Arkansas for Medical Sciences
2 shared publications
In database
- Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing
- Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences
Thidathip Wongsurawat
University of Arkansas for Medical Sciences
2 shared publications
In database
- Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing
- Complete Genome Sequence of a Non-Carbapenemase-Producing Carbapenem-Resistant Providencia rettgeri Strain Isolated from a Clinical Urine Sample in Arkansas
Gunnar Boysen
Winthrop Rockefeller Foundation
2 shared publications
In database
- Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing
- Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences
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