Shi‐Ming Tu
Professor
Also affiliated: The University of Texas MD Anderson Cancer Center (1992–2025); University of Arkansas Medical Center (2022); Central People's Hospital of Zhanjiang (2026); Zhujiang Hospital (2024); Zigong First People's Hospital (2025); Spanish Oncology Genitourinary Group (1986–2022); Huazhong University of Science and Technology (2025); Southern Medical University (2024)
Faculty Researcher
Internal Medicine, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Shi-Ming Tu is a Professor in the Department of Internal Medicine at the University of Arkansas for Medical Sciences. His research focuses on the study of various cancers, including prostate cancer, germ cell tumors, and penile cancer.
Tu's work has involved investigating the efficacy and safety of novel therapeutic agents, such as immune checkpoint inhibitors like pembrolizumab, in advanced and metastatic cancers. He has also examined treatment protocols for recurrent prostate cancer and explored the underlying mechanisms of tumor heterogeneity and plasticity. His research group collaborates with investigators within the University of Arkansas for Medical Sciences and other institutions, including the University of Central Arkansas.
With an h-index of 37 and over 5,100 citations from 137 publications, Tu is recognized as a highly cited researcher. His recent work includes studies on the diagnosis and management of ductal prostate cancer, the role of somatic-type malignancies in testicular germ cell tumors, and preliminary results from precision medicine initiatives.
Metrics
- h-index: 37
- Publications: 137
- Citations: 5,132
Selected Publications
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Real-world analysis of CRS and ICANS following tarlatamab and its association with survival in patients with SCLC. (2026)
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Metabolic health and risk of early-onset cancers in obese young adults: Real-world insights from a large cohort study. (2026)
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Systemic therapy–associated differences in intracranial disease in metastatic prostate cancer: A real-world study. (2026)
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Heterogeneity of cancer prevalence in young adults in the post–COVID-19 era: A multicenter real-world analysis. (2026)
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Real-world effects of sodium-glucose cotransporter 2 inhibitor use on renal cell carcinoma. (2026)
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Real-world effectiveness and safety of enfortumab vedotin plus pembrolizumab versus gemcitabine-platinum chemotherapy in first-line treatment of advanced urothelial carcinoma: A propensity-matched analysis from the TriNetX global network. (2026)
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Real-world comparative outcomes of abiraterone vs enzalutamide in metastatic castration-sensitive prostate cancer (mCSPC): A propensity-matched analysis from the TriNetX Global Health Research Network. (2026)
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Stem Cell Origin of Cancer: Biological Principles and Clinical Strategies for Chemoprevention and Maintenance Therapy in Cancer Care (2025)
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Start Time End Time Integration (STETI): Method for Including Recent Data to Analyze Trends in Kidney Cancer Survival (2025)
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Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers. (2025)
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Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers (2025)
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Epithelioid trophoblastic tumor in male patients with germ cell tumor: A clinicopathologic analysis of five cases (2024)
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Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer (2024)
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Stem Cell Origin of Cancer: Clinical Implications beyond Immunotherapy for Drug versus Therapy Development in Cancer Care (2024)
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Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- S2200, A Phase II Randomized Trial of Cabozantinib (NSC #761968) with or without Atezolizumab (NSC #783608) in Patients with Advanced Papillary Renal Cell Carcinoma (PAPMET2). SouthWest Oncology Group Principal Investigator
- 297214 A Randomized Open-Label Phase 2/3 Study of BT8009 as Monotherapy or in Combination in Participants with Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2) BicycleTx Limited Principal Investigator
Collaboration Network
Top Collaborators
- Stem Cell Theory of Cancer: Implications for Translational Research from Bedside to Bench
- Stem Cell Origin of Cancer: Implications of Oncogenesis Recapitulating Embryogenesis in Cancer Care
- Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics
- Stem Cell Origin of Cancer: Clinical Implications for Cancer Immunity and Immunotherapy
- Stem Cell Origin of Cancer: Clinical Implications beyond Immunotherapy for Drug versus Therapy Development in Cancer Care
Showing 5 of 7 shared publications
- Stem Cell Theory of Cancer: Implications for Translational Research from Bedside to Bench
- Stem-Cell Theory of Cancer: Implications for Antiaging and Anticancer Strategies
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
Showing 5 of 6 shared publications
- Stem Cell Theory of Cancer: Implications for Drug Resistance and Chemosensitivity in Cancer Care
- Stem Cell Theory of Cancer: Origin of Metastasis and Sub-clonality
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
Showing 5 of 6 shared publications
- Stem Cell Origin of Cancer: Implications of Oncogenesis Recapitulating Embryogenesis in Cancer Care
- Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics
- Stem Cell Origin of Cancer: Clinical Implications for Cancer Immunity and Immunotherapy
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Stem Cell Theory of Cancer: Clinical Implications of Epigenomic versus Genomic Biomarkers in Cancer Care
Showing 5 of 6 shared publications
- Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics
- Stem Cell Theory of Cancer: Clinical Implications of Epigenomic versus Genomic Biomarkers in Cancer Care
- Identification of a panel of microRNA biomarkers for the management of patients with refractory germ cell tumor of the testis.
- Origin of extragonadal versus gonadal seminomas.
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
- Stem Cell Origin of Cancer: Implications of Oncogenesis Recapitulating Embryogenesis in Cancer Care
- Stem Cell Origin of Cancer: Clinical Implications for Cancer Immunity and Immunotherapy
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Stem Cell Theory of Cancer: Clinical Implications of Epigenomic versus Genomic Biomarkers in Cancer Care
- Identification of a panel of microRNA biomarkers for the management of patients with refractory germ cell tumor of the testis.
- Stem Cell Origin of Cancer: Implications of Oncogenesis Recapitulating Embryogenesis in Cancer Care
- Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics
- Stem Cell Origin of Cancer: Clinical Implications for Cancer Immunity and Immunotherapy
- Stem Cell Theory of Cancer: Clinical Implications of Epigenomic versus Genomic Biomarkers in Cancer Care
- Identification of a panel of microRNA biomarkers for the management of patients with refractory germ cell tumor of the testis.
- Stem Cell Theory of Cancer: Implications for Drug Resistance and Chemosensitivity in Cancer Care
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers
- Epithelioid trophoblastic tumor in male patients with germ cell tumor: A clinicopathologic analysis of five cases
- Stem Cell Theory of Cancer: Implications for Translational Research from Bedside to Bench
- Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers
- Origin of extragonadal versus gonadal seminomas.
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
- Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers
- Origin of extragonadal versus gonadal seminomas.
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers
- Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers.
- Epithelioid trophoblastic tumor in male patients with germ cell tumor: A clinicopathologic analysis of five cases
- Stem Cell Origin of Cancer: Implications of Oncogenesis Recapitulating Embryogenesis in Cancer Care
- Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics
- Stem Cell Origin of Cancer: Clinical Implications for Cancer Immunity and Immunotherapy
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Germ Cell Tumor of the Testis: Lethal Subtypes of a Curable Cancer
- Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers
- Doxorubicin, paclitaxel, and cisplatin (ATP) for refractory germ cell tumors.
- Epithelioid trophoblastic tumor in male patients with germ cell tumor: A clinicopathologic analysis of five cases
- Stem Cell Theory of Cancer: Implications for Translational Research from Bedside to Bench
- Stem Cell Origin of Cancer: Clinical Implications beyond Immunotherapy for Drug versus Therapy Development in Cancer Care
- Real-world analysis of CRS and ICANS following tarlatamab and its association with survival in patients with SCLC.
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