Konstantinos Arnaoutakis
Sourced from institutional research profiles (UAMS TRI or ARA).
Professor
Also affiliated: Tufts University (2009); University of South Florida (2024); University of Arkansas Medical Center (2013–2026); St. Elizabeth's Medical Center (2008–2009); University of Bristol (2004–2007); Massachusetts General Hospital (2017); Central Arkansas Veterans Healthcare System (2016); Cardiff University (2006–2011); University of Sheffield (2004)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Konstantinos Arnaoutakis' research focuses on cancer, particularly lung and colon neoplasms, and stem cell theory as it relates to cancer. He has investigated treatment patterns and outcomes for patients with ALK+ non-small cell lung cancer and explored the implications of stem cell theory for translational cancer research, drug development, and therapy. Arnaoutakis has also examined the application of genomic data science methods for analyzing rare tumor types and contributed to case reports utilizing genomics, pathomics, and radiomics. His work includes an analysis of a modified frailty index on perioperative morbidity and mortality following endovascular aortic aneurysm repair. Arnaoutakis has published 67 papers, accumulating 621 citations, and holds an h-index of 13. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Bhavesh Mohan Lal and Matthew A. Steliga.
Metrics
- h-index: 13
- Publications: 67
- Citations: 631
Positions
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Professor 2009–presentUniversity of Arkansas for Medical Sciences Internal Medicine ORCID
Selected Publications
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Association Between Metabolic Syndrome and Prostate Cancer: A Systematic Review (2026)
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DLL3-targeted therapy with tarlatamab in small cell lung cancer across lines of therapy: A systematic review of prospective and randomized clinical trials. (2026)
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Incidentally Detected Pulmonary Carcinoid Tumorlet With Coexisting Carcinoid Tumorlet in the Mediastinal Lymph Node in a Patient With Lung Cancer (2025)
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Optical imaging of treatment-naïve human NSCLC reveals changes associated with metastatic recurrence (2024)
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Guide to Understanding and Supporting International Medical Graduates in Hematology/Oncology by the ASCO International Medical Graduates Community of Practice (2024)
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Real-World Treatment Patterns and Outcomes Across Three Lines of Therapy in Patients with ALK+ NSCLC (2024)
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Stem Cell Origin of Cancer: Clinical Implications beyond Immunotherapy for Drug versus Therapy Development in Cancer Care (2024)
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An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics (2023)
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PP01.55 Real-World Treatment Sequencing and Impact on Outcomes in ALK-Positive (ALK+) Non–Small Cell Lung Cancer (NSCLC) (2023)
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Stem Cell Theory of Cancer: Implications for Translational Research from Bedside to Bench (2022)
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Abstract 5038: Applying reproducible genomic data science methods for the analysis of a rare tumor type (2022)
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Hematology/Oncology Fellowship Programs' Participation in the Quality Oncology Practice Initiative (2022)
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Depression in lung cancer patients: A nationwide analysis. (2019)
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Absolute lymphocyte count (ALC) as predictor of Pneumocystis Jiroveci Pneumonia (PCP) infection in patients on immune checkpoint inhibitors (ICPi). (2019)
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A novel prostate cancer immunotherapy using prostate-specific antigen peptides and Candida skin test reagent as an adjuvant (2018)
Grants & Funding
As listed on this researcher's institutional profile.
- Pfizer A7471009, A Randomized Double Blind Phase 3 Efficacy and Safety Study of PF-00299804 versus Erlotinib for the Treatment of Advanced Non-Small C Pfizer, Inc.
- Phase 2, Open-Label Single Arm Study of the Efficacy and Safety of PF-02341066 in Pfizer, Inc.
- Phase III, Randomized, Open-Label Study of the Efficacy and Safety of PF-02341066 Versus Standard of Care Chemotherapy (Pemetrexed or Docetaxel) in Pa Pfizer, Inc.
- S1900C: A Phase II Study of Talazoparib Plus Avelumab in Patients with Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer Bearing Pathogenic STK11 Genomic Alterations (LUNG-MAP Sub-Study) (260760) NIH/Nat. Cancer Institute via SouthWest Oncology Group
- S1929, Phase II Randomized Study of Maintenance Atezolizumab Versus Atezolizumab in Combination with Talazoparib in Patients with SLFN11 Positive Extensive Stage Small Cell Lung Cancer (ES-SCLC) (273385) Southwest Oncology Group-Clinical Trial Initiative
- A Phase 2, Randomized, Open Label Study of Figitumumab (CP-751,871) Plus Cisplatin (or Carboplatin) and Etoposide, Versus Cisplatin (or Carboplatin) a Pfizer, Inc.
- A randomized, open-label, Phase II, 2-arm multi-center trial comparing maintenance therapy with pazopanib or pemetrexed in non-progressing subjects wi GlaxoSmithKline
- A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of Tarlatamabin Subjects with Relapsed/Refractory Small Cell Lung Cancer After Two or More Prior Lines of Treatment (DeLLphi-301) Amgen, Inc.
- An Open Label, Multi-center, IRESSA™ Clinical Access Program of Gefitinib 250 mg AstraZeneca
- An International Phase 3 Randomized Trial of Autologous Dendritic Cell Immunother Argos Therapeutics, Inc
- A Randomized, Open-label, Phase III Study to Evaluate the Efficacy and safety of Boehringer Ingleheim Pharmaceuticals, Inc.
- S1900G, “A Randomized Phase II Study of INC280 (capmatinib) plusOsimertinib with or without Ramucirumab in Participants with EGFR-Mutant, METAmplifiedStage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)” SouthWest Oncology Group
- Health Literacy and Emergency Preparedness Programs for Medicaid Recipients in Rural Arkansas US Department of Agriculture via University of Arkansas Division of Agriculture Cooperative Extension Service
- A Randomized, Double-Blind, Phase 2, Dose-Ranging Study to Evaluate the Safety and Efficacy of Veliparib and Whole Brain Radiation Therapy versus Plac AbbVie Inc
- A Randomized, Open-label, Phase III Study to Evaluate the Efficacy and safety of Oral Afatinib (BIBW 2992) Versus Intravenous Methotrexate in Patients Boehringer Ingleheim Bioproducts
- 297894: A Randomized Open-Label Phase 3 Study of Adjuvant Pembrolizumab With or Without MK-2870 in Patients With Resectable Stage II to IIIB (N2) NSCLC Not Achieving pCR After Neoadjuvant Pembrolizumab Plus Platinum-Based Chemotherapy and Surgery Merck & Company, Inc.
- A Randomized, Controlled Phase III Study Investigating IMA901 Multipeptide Cancer Vaccine in Patients receiving Sunitinib as First-Line Therapy for Ad Immatics Biotechnologies
- S2302, PRAGMATICA – LUNG: “A Prospective Randomized Study of Ramucirumab (LY3009806; NSC 749128) plus Pembrolizumab (MK-3475; NSC 776864) versus Standard of Care for Participants Previously Treated with Immunotherapy for Stage IV SouthWest Oncology Group
Collaboration Network
Top Collaborators
- Targeting nano drug delivery to cancer cells using tunable, multi‐layer, silver‐decorated gold nanorods
- Cancer patient perspectives regarding preparedness for end-of-life care: A qualitative study
- Addressing Opioid-Associated Constipation Using Quality Oncology Practice Initiative Scores and Plan-Do-Study-Act Cycles
- Rituximab and intermediate-purity plasma-derived factor VIII concentrate (Koate®) as adjuncts to therapeutic plasma exchange for thrombotic thrombocytopenic purpura in patients with an ADAMTS13 inhibitor
- Hematology/Oncology Fellowship Programs' Participation in the Quality Oncology Practice Initiative
Showing 5 of 11 shared publications
- Cancer patient perspectives regarding preparedness for end-of-life care: A qualitative study
- Treatments for metastatic hormone-sensitive prostate cancer: A systematic review.
- Absolute lymphocyte count (ALC) as predictor of Pneumocystis Jiroveci Pneumonia (PCP) infection in patients on immune checkpoint inhibitors (ICPi).
- Metastatic Renal Cell Carcinoma Presenting as Painful Chewing Successfully Treated with Combined Nivolumab and Sunitinib
- Integrating Collaborative Learning and Competition in a Hematology/Oncology Training Program
Showing 5 of 8 shared publications
- PARP1 Is Up-Regulated in Non-small Cell Lung Cancer Tissues in the Presence of the Cyanobacterial Toxin Microcystin
- Liquid biopsy and its role in an advanced clinical trial for lung cancer
- Hyalinizing Clear Cell Carcinoma of the Lung
- An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics
- Accuracy of fine needle aspiration and core lung biopsies to predict histology in patients with non-small cell lung cancer
Showing 5 of 7 shared publications
- Liquid biopsy and its role in an advanced clinical trial for lung cancer
- Cancer patient perspectives regarding preparedness for end-of-life care: A qualitative study
- Rituximab and intermediate-purity plasma-derived factor VIII concentrate (Koate®) as adjuncts to therapeutic plasma exchange for thrombotic thrombocytopenic purpura in patients with an ADAMTS13 inhibitor
- Integrating Collaborative Learning and Competition in a Hematology/Oncology Training Program
- Abstract 2889: Human antibodies induced by vaccination with a carbohydrate mimetic-peptide vaccine show functional anti-tumor activity on human lung-cancer cells
- Improving Communication on Intent of Chemotherapy Using QOPI Scores and PDSA Cycles
- Metastatic Renal Cell Carcinoma Presenting as Painful Chewing Successfully Treated with Combined Nivolumab and Sunitinib
- A novel prostate cancer immunotherapy using prostate-specific antigen peptides and Candida skin test reagent as an adjuvant
- A novel prostate cancer immunotherapy using prostate specific antigen peptides and Candida skin test reagent as an immunostimulant.
- Primary bone marrow Hodgkin lymphoma in an HIV-negative patient
- An Unusual Case of Acute Promyelocytic Leukemia Presenting With Hypoplastic Bone Marrow and Pancytopenia
- Primary Bone Marrow Classical Hodgkin Lymphoma in HIV- Negative Population: Aggressive but Amenable
- Primary Bone Marrow Classical Hodgkin Lymphoma in HIV- Negative Population: Aggressive but Amenable
- Cancer patient perspectives regarding preparedness for end-of-life care: A qualitative study
- Absolute lymphocyte count (ALC) as predictor of Pneumocystis Jiroveci Pneumonia (PCP) infection in patients on immune checkpoint inhibitors (ICPi).
- A novel prostate cancer immunotherapy using prostate-specific antigen peptides and Candida skin test reagent as an adjuvant
- A novel prostate cancer immunotherapy using prostate specific antigen peptides and Candida skin test reagent as an immunostimulant.
- Rituximab and intermediate-purity plasma-derived factor VIII concentrate (Koate®) as adjuncts to therapeutic plasma exchange for thrombotic thrombocytopenic purpura in patients with an ADAMTS13 inhibitor
- A novel prostate cancer immunotherapy using prostate-specific antigen peptides and Candida skin test reagent as an adjuvant
- A novel prostate cancer immunotherapy using prostate specific antigen peptides and Candida skin test reagent as an immunostimulant.
- Improving Communication on Intent of Chemotherapy Using QOPI Scores and PDSA Cycles
- Therapeutic Implications of Angiogenesis in Cancer
- A Quality Improvement project to decrease overuse of vancomycin in an inpatient Hematology/Oncology service.
- Addressing Opioid-Associated Constipation Using Quality Oncology Practice Initiative Scores and Plan-Do-Study-Act Cycles
- Improving Communication on Intent of Chemotherapy Using QOPI Scores and PDSA Cycles
- Integrating Collaborative Learning and Competition in a Hematology/Oncology Training Program
- Primary bone marrow Hodgkin lymphoma in an HIV-negative patient
- CMV esophagitis: sequelae of radiation therapy
- Primary Bone Marrow Classical Hodgkin Lymphoma in HIV- Negative Population: Aggressive but Amenable
- Absolute lymphocyte count (ALC) as predictor of Pneumocystis Jiroveci Pneumonia (PCP) infection in patients on immune checkpoint inhibitors (ICPi).
- Accuracy of fine needle aspiration and core lung biopsies to predict histology in patients with non-small cell lung cancer
- Aggressive care at the end of life: A study of practice based factors in patients with stage IV cancer.
- Targeting nano drug delivery to cancer cells using tunable, multi‐layer, silver‐decorated gold nanorods
- Integrating Collaborative Learning and Competition in a Hematology/Oncology Training Program
- Aggressive care at the end of life: A study of practice based factors in patients with stage IV cancer.
- Liquid biopsy and its role in an advanced clinical trial for lung cancer
- An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics
- Abstract 5038: Applying reproducible genomic data science methods for the analysis of a rare tumor type
- Liquid biopsy and its role in an advanced clinical trial for lung cancer
- An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics
- Abstract 5038: Applying reproducible genomic data science methods for the analysis of a rare tumor type
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