Gustavo Vaca-Diez Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Senior Research Assistant
University of Arkansas at Fayetteville
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Biography and Research Information
OverviewAI-generated summary
Gustavo Vaca-Diez's research focuses on the development and application of microphysiological systems to study cardiovascular diseases, particularly calcific aortic valve disease. His work utilizes a three-dimensional valve-on-chip microphysiological system to investigate the progression of this condition and identify potential biomarkers. Recent publications explore how cell cycle progression, cholesterol metabolism, and protein homeostasis are implicated in early calcific aortic valve disease. Additionally, his research investigates the mechanosensitive pathways affected by physiological and pathological strain on valve cells within this novel human valve-on-chip system.
Vaca-Diez collaborates with researchers at the University of Arkansas at Fayetteville, including Kartik Balachandran, Ishita Tandon, Alan E. Woessner, and Patrick Kuczwara. He has authored six publications with 38 citations and an h-index of 2. His research is characterized by its active and recent contributions to the field.
Metrics
- h-index: 2
- Publications: 6
- Citations: 38
Selected Publications
- Elucidating the mechanosensitive pathways of physiological and pathological strain on valve cells in a novel human valve-on-chip system (2025) DOI
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression (2024) DOI
- A Three-Dimensional Valve-on-Chip Microphysiological System Reveals Novel Biomarkers of Early Calcific Aortic Valve Disease Progression (2023) DOI
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