Samir V. Jenkins
Role not yet determined Is this you? Add your title
Also affiliated: United States Food and Drug Administration (2015); University of Arkansas Medical Center (2023–2025); Yale University (2008); ORCID (2020)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Samir V. Jenkins' research focuses on the application of nanomaterials in therapeutic and diagnostic contexts, particularly in cancer treatment. His work investigates the photothermal properties of gold nanostructures and their conversion into self-assembled ionic nanomaterials for enhanced therapeutic effects. Jenkins has explored the use of nanocage-coated artificial extracellular matrices to promote neural stem cell differentiation and the nanoscale control of photothermal action in gold nanostructure-coated surfaces.
His research also extends to drug delivery systems, including liposome formulations for tumor-targeted delivery in conjunction with radiation therapy. Jenkins has examined the molecular mechanisms underlying cancer progression and dormancy, including the role of specific proteins in inducing reversible dormancy in lung tumor cells and the exosomal profiles of hepatocellular carcinoma cells. He has also investigated bystander effects in spatially fractionated radiation therapy and the proinflammatory activity of VEGF-targeted treatments.
Jenkins leads a research group and collaborates with researchers at the University of Arkansas for Medical Sciences, including Ruud P.M. Dings, Robert Griffin, and Azemat Jamshidi‐Parsian, as well as Narasimhan Rajaram at the University of Arkansas at Fayetteville. His scholarly output is characterized by a high h-index of 21 and over 1,400 citations across 75 publications, designating him as a highly cited researcher.
Metrics
- h-index: 21
- Publications: 73
- Citations: 1,386
Selected Publications
-
Synthesis of Peptide Analogs From Fish Venom With Potential Antimicrobial and Anticancer Activity (2026)
-
Abstract 4785: Thermal regulation of dysbiotic tumor vasculature (2026)
-
Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026)
-
CB-839 induces reversible dormancy in lung tumor-cells (2024)
-
Interrogating the Role of Endocytosis Pathway and Organelle Trafficking for Doxorubicin-Based Combination Ionic Nanomedicines (2024)
-
Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications (2024)
-
Abstract 186: Tumor exosome-macrophage interactions: The role of tumor-associated glycans and scavenger receptor class A (2024)
-
Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials (2023)
-
Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells (2023)
-
General principles of SFRT biology (2023)
-
Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes (2023)
-
Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking (2023)
-
Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking (2023)
-
Proteomic Analysis of Transcription Factors Involved in the Alteration of Ischemic Mouse Heart as Modulated by MSC Exosomes (2023)
-
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy (2022)
Collaboration Network
Top Collaborators
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Sample storage conditions induce post-collection biases in microbiome profiles
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
Showing 5 of 32 shared publications
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Sample storage conditions induce post-collection biases in microbiome profiles
Showing 5 of 23 shared publications
- Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs
- Anisotropic Seeded Growth of Cu–M (M = Au, Pt, or Pd) Bimetallic Nanorods with Tunable Optical and Catalytic Properties
- Gold Nanocage-Photosensitizer Conjugates for Dual-Modal Image-Guided Enhanced Photodynamic Therapy
- Synthesis of Hollow Gold–Silver Alloyed Nanoparticles: A “Galvanic Replacement” Experiment for Chemistry and Engineering Students
- Versatility of targeted antibiotic-loaded gold nanoconstructs for the treatment of biofilm-associated bacterial infections
Showing 5 of 17 shared publications
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation
- Enhanced Photothermal Treatment Efficacy and Normal Tissue Protection via Vascular Targeted Gold Nanocages
- Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
Showing 5 of 11 shared publications
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Sample storage conditions induce post-collection biases in microbiome profiles
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors
- Abstract LB-312: Breast cancer targeting by theranostic gold nanorods
Showing 5 of 8 shared publications
- Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces
- Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
- Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials
Showing 5 of 6 shared publications
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells
- A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro
- Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance
- Rapid quantification of mitochondrial fractal dimension in individual cells
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- CB-839 induces reversible dormancy in lung tumor-cells
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Versatility of targeted antibiotic-loaded gold nanoconstructs for the treatment of biofilm-associated bacterial infections
- Abstract LB-312: Breast cancer targeting by theranostic gold nanorods
- Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells
- A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro
- Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance
- Rapid quantification of mitochondrial fractal dimension in individual cells
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation
- Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces
- Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials
- Nanoscale Investigation and Control of Photothermal Action of Gold Nanostructure-coated Surfaces
- Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs
- Plasmonic Nanostructures for Biomedical and Sensing Applications
- Molecule-specific darkfield and multiphoton imaging using gold nanocages
Similar Researchers
Based on overlapping research topics