Narasimhan Rajaram Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI High Impact

Professor

University of Arkansas at Fayetteville

faculty

24 h-index 125 pubs 1,855 cited

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Biography and Research Information

OverviewAI-generated summary

Narasimhan Rajaram is a professor at the University of Arkansas at Fayetteville. His research program focuses on the application of optical spectroscopy techniques, particularly diffuse reflectance spectroscopy, for biomedical applications. He has investigated the use of these methods for monitoring tumor response to various treatments, including immunotherapy and radiation, and for characterizing the tumor microenvironment. His work also extends to evaluating differences in optical properties between indolent and aggressive murine breast tumors and assessing heat stress-induced changes in biological tissues.

Rajaram has received significant federal funding for his research. He is the Principal Investigator (PI) on an NIH/National Institute of General Medical Sciences grant totaling $2,103,742 for the Arkansas Integrative Metabolic Research Center. Additionally, he is PI on an NIH/National Cancer Institute grant of $251,222 for the determination of functional and molecular biomarkers of treatment resistance with multimodal optical spectroscopy, and an NSF grant of $50,000 for developing a multimodal imaging platform to image bioenergetics in live tissue.

His scholarly contributions are reflected in a publication record of 125 papers, with an h-index of 24 and over 1,855 citations. Rajaram collaborates with researchers at the University of Arkansas at Fayetteville, including Joel Rodríguez Troncoso and Jesse D. Ivers, and at the University of Arkansas for Medical Sciences, including Samir V. Jenkins.

Metrics

  • h-index: 24
  • Publications: 125
  • Citations: 1,855

Selected Publications

  • Metabolic Imaging and Characterization of Multicomponent Spheroid Models in Vitro. (2025) DOI
  • Advancing Optical Techniques for Cancer Diagnosis and Therapy Monitoring (2025) DOI
  • Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling (2025) DOI
  • Investigating Biomarkers of Radiation Resistance in Head and Neck Cancer Using Raman Spectroscopy (2025) DOI
  • Investigating Tissue Changes Due to Alcohol and Tobacco Consumption Using Optical Spectroscopy (2025) DOI
  • Design and Validation of a Multimodal Diffuse Reflectance and Spatially Offset Raman Spectroscopy System for In Vivo Applications (2024) DOI
  • Erratum: Investigating the relationship between hypoxia, hypoxia-inducible factor 1, and the optical redox ratio in response to radiation therapy (2024) DOI
  • Optical imaging of treatment-naïve human NSCLC reveals changes associated with metastatic recurrence (2024) DOI
  • Investigating In Vivo Tumor Biomolecular Changes Following Radiation Therapy Using Raman Spectroscopy (2024) DOI
  • Noncontact Diffuse Reflectance Spectroscopy of Synovial Fluid Samples for Rapid Identification of Infections (2024) DOI
  • Rapid Optical Sensing of Infection in Joint Fluids (2024) DOI
  • Design and Validation of a Multimodal Spatially Offset System Comprising Diffuse Reflectance Spectroscopy and Raman Spectroscopy (2024) DOI
  • Investigating the relationship between hypoxia, hypoxia-inducible factor 1, and the optical redox ratio in response to radiation therapy (2024) DOI
  • Racial and skin color mediated disparities in pulse oximetry in infants and young children (2024) DOI
  • Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance (2023) DOI

Federal Grants 3 $2,404,964 total

NIH/National Institute of General Medical Sciences Contact PI Apr 2021 - Feb 2027

Arkansas Integrative Metabolic Research Center

National Institute of General Medical Sciences $2,103,742 P20
NIH/National Cancer Institute Contact PI Aug 2019 - Jul 2026

Determination of functional and molecular biomarkers of treatment resistance with multimodal optical spectroscopy

National Cancer Institute $251,222 R01

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