X. Zhang

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NCTR

Also affiliated: Florida State University (2012); United States Food and Drug Administration (2010–2021); Massachusetts General Hospital (2010–2012)

6 h-index 12 pubs 228 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

X. Zhang's research focuses on the neurochemical effects of methylphenidate, a medication often prescribed for attention deficit hyperactivity disorder (ADHD). Zhang has investigated the long-term impacts of this drug on the brains of nonhuman primates, utilizing positron-emission tomography (PET) imaging techniques to assess changes in neurotransmitter systems, specifically dopamine. Their work has explored the consequences of discontinuing methylphenidate after prolonged exposure, contributing to an understanding of potential withdrawal effects and long-term brain function following cessation of treatment. Zhang's research is supported by collaborations with researchers at the National Center for Toxicological Research and the University of Arkansas for Medical Sciences. Zhang has authored 12 publications with a total of 218 citations and an h-index of 5.

Metrics

h-index: 6
Publications: 12
Citations: 228

Selected Publications

Discontinuation of methylphenidate after long-term exposure in nonhuman primates (2023)

Neurotoxicology and Teratology 4 citations DOI OpenAlex
MicroPET/CT assessment of neurochemical effects in the brain after long-term methylphenidate treatment in nonhuman primates (2021)

Neurotoxicology and Teratology 8 citations DOI OpenAlex
Molecular Imaging: A New Frontier in Neurotoxicology (2017)

Elsevier eBooks 2 citations DOI OpenAlex
MicroPET/CT assessment of FDG uptake in brain after long-term methylphenidate treatment in nonhuman primates (2016)

Neurotoxicology and Teratology 9 citations DOI OpenAlex
Evaluating neural progenitor cell proliferation following sevoflurane exposure in developing rat brain using PET imaging of [18F] fluoro-l-thymidine (2014)

Neurotoxicology and Teratology DOI OpenAlex
Minimally invasive quantitative assessment of inhalation anesthetic-induced brain cell death using microPET imaging (2011)

Toxicology Letters DOI OpenAlex
In Vivo Systems: Animal Models of Neurodegeneration* (2010)

Elsevier eBooks 1 citation DOI OpenAlex
Changes in gene expression after phencyclidine administration in developing rats: a potential animal model for schizophrenia (2010)

International Journal of Developmental Neuroscience 30 citations DOI OpenAlex
MicroPET imaging of ketamine-induced neuronal apoptosis with radiolabeled DFNSH (2010)

Journal of Neural Transmission 36 citations DOI OpenAlex