William Slikker Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Director

NCTR

Last publication 2025 Last refreshed 2026-05-16

faculty

67 h-index 480 pubs 19,656 cited

Research Areas

Links

ORCID Lab Website

OverviewAI-generated summary

William Slikker directs research focused on regulatory science, with a particular emphasis on toxicology and the application of emerging technologies. His work has explored the regulatory landscape of nanotechnology and nanoplastics from a global perspective, and the impact of new technologies on regulatory science frameworks. He has also investigated the intersection of artificial intelligence, real-world data, and public health, specifically in the context of drug and food safety.

Slikker's research extends to neuroprotection and neurotoxicity. He has studied the neurochemical effects of long-term methylphenidate treatment in nonhuman primates using microPET/CT imaging. His laboratory has also focused on establishing neural stem cells from fetal monkey brains for neurotoxicity testing and has investigated the neuroprotective potential of carnitine. His work also includes the transition from traditional animal models to New Approach Methodologies (NAMs) to protect human and animal health.

With an h-index of 67 and over 480 publications, Slikker is recognized as a highly cited researcher. His key collaborators include Tucker A. Patterson, Leah E. Latham, John Talpos, and Weida Tong, all from the National Center for Toxicological Research. He maintains an active laboratory website to disseminate his research.

Metrics

h-index: 67
Publications: 480
Citations: 19,656

Selected Publications

Proposed key characteristics of neurotoxic chemicals (2025)

DOI OpenAlex
Realizing Impact of Artificial Intelligence in Real World Enhances Public Health (2025)

DOI OpenAlex
Biomarkers of Neurotoxicity and Disease (2025)

1 citation DOI OpenAlex
Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods (2024)

27 citations DOI OpenAlex
Integrating artificial intelligence with bioinformatics promotes public health (2023)

3 citations DOI OpenAlex
In pursuit of precision medicine for brain injury and neurotoxicity and improved protection of human health (2023)

DOI OpenAlex
Society for birth defects research and prevention's multidisciplinary research needs workshop 2022: A call to action (2023)

DOI OpenAlex
Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing (2023)

3 citations DOI OpenAlex
Artificial intelligence and real-world data for drug and food safety – A regulatory science perspective (2023)

37 citations DOI OpenAlex
Discontinuation of methylphenidate after long-term exposure in nonhuman primates (2023)

3 citations DOI OpenAlex
Application of Nonhuman Primate Models in the Studies of Pediatric Anesthesia Neurotoxicity (2022)

5 citations DOI OpenAlex
Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits (2022)

DOI OpenAlex
Analysis of biofluid lipid changes: potential biomarkers for detecting central nervous system diseases and neurotoxicity (2021)

2 citations DOI OpenAlex
MicroPET/CT assessment of neurochemical effects in the brain after long-term methylphenidate treatment in nonhuman primates (2021)

7 citations DOI OpenAlex
Regulatory landscape of nanotechnology and nanoplastics from a global perspective (2021)

370 citations DOI OpenAlex