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Current · Arkansas
Last published
2026
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OpenAlex · ORCID
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2026-10-06
J
Jinchun Sun
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
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Also affiliated: Jiangnan University (2004–2005); United States Department of Health and Human Services (2012); United States Food and Drug Administration (2008–2026); University of Kentucky (2007–2009); Chinese Academy of Sciences (2020); Institute of Oceanology (2020); Qingdao National Laboratory for Marine Science and Technology (2020); University of Chinese Academy of Sciences (2020); Lanzhou University (1998–2000)
26 h-index
61 pubs
1,857 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jinchun Sun's research focuses on the application of metabolomics and mass spectrometry techniques to identify biomarkers for drug-induced toxicity, particularly in the liver and kidneys. Their work has investigated the metabolic changes associated with acetaminophen exposure in both animal models and human patients. Studies have utilized Nuclear Magnetic Resonance (NMR) and Ultra-Performance Liquid Chromatography coupled with Mass Spectrometry (UPLC/MS) to evaluate these alterations.
Sun has explored the use of metabolomics in understanding acute kidney injury in children following cardiac surgery and in adults. Additionally, their research has examined age-related changes in urinary composition in male Sprague Dawley rats and the impact of different data normalization methods on statistical analysis. Sun has a publication record that includes work on reference materials for quality assurance in metabolomics and lipidomics research.
Key collaborators include Richard D. Beger, Laura K. Schnackenberg, and Lisa Pence, all affiliated with the National Center for Toxicological Research. Sun has authored 61 publications with a total of 1,846 citations and an h-index of 26.
Metrics
- h-index: 26
- Publications: 61
- Citations: 1,857
Selected Publications
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Integrated miR-omics and proteomics reveal the regulatory role of miR in protein networks associated with COVID-19 disease progression (2026)
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Assessing the developmental effects of fentanyl and impacts on lipidomic profiling using neural stem cell models (2025)
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Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers (2024)
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Metabolomics evaluation of the photochemical impact of violet-blue light (405 nm) on ex vivo platelet concentrates (2023)
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Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice (2022)
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Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC) (2022)
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Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy (2021)
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Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients (2021)
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Bile Acid Profile and its Changes in Response to Cefoperazone Treatment in MR1 Deficient Mice (2020)
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Metabolomics Test Materials for Quality Control: A Study of a Urine Materials Suite (2019)
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Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection (2019)
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Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach (2019)
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Metabolomics‐based pathway changes in testis fragments treated with ethinylestradiol in vitro (2019)
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Evaluation of the Performance of Lipidyzer Platform and Its Application in the Lipidomics Analysis in Mouse Heart and Liver (2019)
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An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma (2019)
Collaboration Network
Top Collaborators
Richard D. Beger
National Center for Toxicological Research
44 shared publications
In database
- Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity
- Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)
- Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS
- Metabonomics of acute kidney injury in children after cardiac surgery
- Serum metabolomic profiles from patients with acute kidney injury: A pilot study
Showing 5 of 44 shared publications
Laura K. Schnackenberg
National Center for Toxicological Research
30 shared publications
In database
- Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity
- Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS
- Metabonomics of acute kidney injury in children after cardiac surgery
- Serum metabolomic profiles from patients with acute kidney injury: A pilot study
- Translational biomarkers of acetaminophen-induced acute liver injury
Showing 5 of 30 shared publications
Zhijun Cao
National Center for Toxicological Research
10 shared publications
In database
- Proteomic analysis of acetaminophen-induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Evaluation of the Performance of Lipidyzer Platform and Its Application in the Lipidomics Analysis in Mouse Heart and Liver
- Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach
- An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma
Showing 5 of 10 shared publications
Lisa Pence
National Center for Toxicological Research
9 shared publications
In database
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach
- An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma
- Metabolomics evaluation of hydroxyproline as a potential marker of melamine and cyanuric acid nephrotoxicity in male and female Fischer F344 rats
- Metabolomic analysis of urine from rats chronically dosed with acrylamide using NMR and LC/MS
Showing 5 of 9 shared publications
Thomas Schmitt
National Center for Toxicological Research (US)
8 shared publications
- Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS
- Evaluation of the Performance of Lipidyzer Platform and Its Application in the Lipidomics Analysis in Mouse Heart and Liver
- Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach
- An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma
- Comprehensive analysis of alterations in lipid and bile acid metabolism by carbon tetrachloride using integrated transcriptomics and metabolomics
Showing 5 of 8 shared publications
Li‐Rong Yu
National Center for Toxicological Research (US)
8 shared publications
- Proteomic analysis of acetaminophen-induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach
- An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma
- Aptamer-Based Proteomics Identifies Mortality-Associated Serum Biomarkers in Dialysis-Dependent AKI Patients
Showing 5 of 8 shared publications
Xi Yang
National Center for Toxicological Research (US)
7 shared publications
- Translational biomarkers of acetaminophen-induced acute liver injury
- Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans
- Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice
- Proteomic analysis of acetaminophen-induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury
- Evaluating effects of penicillin treatment on the metabolome of rats
Showing 5 of 7 shared publications
Sudeepa Bhattacharyya
Arkansas Children's Hospital
6 shared publications
In database
- Translational biomarkers of acetaminophen-induced acute liver injury
- Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans
- Metabolomics evaluation of hydroxyproline as a potential marker of melamine and cyanuric acid nephrotoxicity in male and female Fischer F344 rats
- Metabolomics Analysis of Urine Samples from Children after Acetaminophen Overdose
- Metabolomic analysis of urine from rats chronically dosed with acrylamide using NMR and LC/MS
Showing 5 of 6 shared publications
Didier Portilla
University of Virginia (US)
6 shared publications
- Metabonomics of acute kidney injury in children after cardiac surgery
- Serum metabolomic profiles from patients with acute kidney injury: A pilot study
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Aptamer-Based Proteomics Identifies Mortality-Associated Serum Biomarkers in Dialysis-Dependent AKI Patients
- Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy
Showing 5 of 6 shared publications
William F. Salminen
National Center for Toxicological Research (US)
5 shared publications
- Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice
- Proteomic analysis of acetaminophen-induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury
- Evaluating effects of penicillin treatment on the metabolome of rats
- Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity
- Comprehensive analysis of alterations in lipid and bile acid metabolism by carbon tetrachloride using integrated transcriptomics and metabolomics
Ricky D. Holland
National Center for Toxicological Research (US)
5 shared publications
- Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS
- Metabonomics of acute kidney injury in children after cardiac surgery
- Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis
- Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies
- Corrigendum to “Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS” [J. Chromatogr. B 871 (2008) 328]
Jaclyn R. Daniels
National Center for Toxicological Research
5 shared publications
In database
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach
- An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma
- Aptamer-Based Proteomics Identifies Mortality-Associated Serum Biomarkers in Dialysis-Dependent AKI Patients
- An Aptamer‐Based Approach to Assess the Human Plasma Proteome for Pre‐Analytical Variability
James Greenhaw
National Center for Toxicological Research
4 shared publications
In database
- Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice
- Evaluating effects of penicillin treatment on the metabolome of rats
- Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity
- Comprehensive analysis of alterations in lipid and bile acid metabolism by carbon tetrachloride using integrated transcriptomics and metabolomics
Donna L. Mendrick
National Center for Toxicological Research
4 shared publications
In database
- Proteomic analysis of acetaminophen-induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury
- Evaluating effects of penicillin treatment on the metabolome of rats
- Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity
- Comprehensive analysis of alterations in lipid and bile acid metabolism by carbon tetrachloride using integrated transcriptomics and metabolomics
Huizhong Chen
National Center for Toxicological Research
4 shared publications
In database
- Evaluation of metabolism of azo dyes and their effects onStaphylococcus aureusmetabolome
- Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena
- Bile Acid Profile and its Changes in Response to Cefoperazone Treatment in MR1 Deficient Mice
- Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice
Similar Researchers
Based on overlapping research topics
Laura K. Schnackenberg
National Center for Toxicological Research
Metabolomics and Mass Spectrometry Techniques
Drug-Induced Hepatotoxicity and Protection
Acute Kidney Injury
Pritmohinder S. Gill
University of Arkansas for Medical Sciences
Drug-Induced Hepatotoxicity and Protection
Acute Kidney Injury
Biomarkers
Richard D. Beger
National Center for Toxicological Research
Metabolomics and Mass Spectrometry Techniques
Drug-Induced Hepatotoxicity and Protection
Biomarkers
Lisa M. Pence
National Center for Toxicological Research
Metabolomics and Mass Spectrometry Techniques
Acute Kidney Injury
Biomarkers
Grover Paul Miller
University of Arkansas for Medical Sciences
Metabolomics and Mass Spectrometry Techniques
Drug-Induced Hepatotoxicity and Protection
Pharmacological Effects and Toxicity Studies
J. A. Hinson
University of Arkansas for Medical Sciences
Metabolomics and Mass Spectrometry Techniques
Drug-Induced Hepatotoxicity and Protection
Pharmacological Effects and Toxicity Studies