Jeffrey B. Stambough
Assistant Professor, Adult Reconstruction
Also affiliated: University of Southern California (2025); Hospital for Special Surgery (2018); Barnes-Jewish Hospital (2013–2015); American Academy of Orthopaedic Surgeons (2022); University of Wisconsin–Madison (2022); University of Arizona (2025); Thomas Jefferson University (2025); Washington University in St. Louis (2013–2018); Cornell University (2004); University of Arkansas Medical Center (2023–2025); Hospital of the University of Pennsylvania (2012); Smith & Nephew (United States) (2025); Zimmer Biomet (United States) (2018); Cincinnati Sportsmedicine and Orthopaedic Center (2009); OrthoCarolina (2017–2022); University of Wisconsin Health (2022); Stanford Medicine (2018); OrthoCarolina Research Institute (2018–2022); Deaconess Hospital (2000–2004); University of Cincinnati (2004–2010); University of Pennsylvania (2008–2012); Stanford University (2018–2022)
Orthopaedics Surgery, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Jeffrey B. Stambough's research focuses on investigating cost-saving strategies and clinical outcomes in joint arthroplasty, as well as treatments for infected joints and novel surgical instrumentation for complex joint replacement. His clinical interests include arthritis of the hip and knee, hip and knee arthroscopy, hip and knee problems, hip and knee infections, hip pain, hip replacement, knee pain, and knee replacement. He also addresses periprosthetic fractures, which are fractures around hip or knee implants.
Stambough has a background in basic science research from his time at the National Institutes of Health and the McKay Orthopaedic Research Laboratory. He has published on topics including rapid recovery protocols for primary total hip arthroplasty, the impact of the COVID-19 pandemic on elective hip and knee arthroplasty, and decolonization protocols for primary total joint arthroplasty. He is also an author on publications related to the American Joint Replacement Registry annual reports.
His scholarly metrics include an h-index of 28, with over 200 publications and nearly 3,000 citations. He leads a research group and collaborates with several colleagues at the University of Arkansas for Medical Sciences, including Simon C. Mears, C. Lowry Barnes, and Benjamin M. Stronach.
Research Overview
Clinical Interests Include: Arthritis of the Hip and Knee Hip & Knee Arthoscopy Hip & Knee Problems Hip and knee infections Hip Pain Hip Replacement Knee Arthroscopy Knee pain Knee Replacement Periprosthetic fractures (fractures around hip or knee implants
Metrics
- h-index: 29
- Publications: 224
- Citations: 3,058
Positions
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Associate Professor 2023–presentUniversity of Arkansas for Medical Sciences Orthopaedic Surgery ORCID
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Assistant Professor, Adult Reconstruction publications 2017–2026University of Arkansas for Medical Sciences Orthopaedics Surgery, College of Medicine Institutional directory
Selected Publications
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Is Robotic-assisted THA Associated With Decreased Risk of All-cause Revision or Revision for Dislocation? An Analysis of the American Joint Replacement Registry (2026)
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Periarticular Injection for Pain Control after Surgical Treatment of Knee Periprosthetic Joint Infection (2026)
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Implant Costs Consume a Large Proportion of the Reimbursement in Revision Hip and Knee Arthroplasties (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Mixing Components from Different Manufacturers in Total Hip Arthroplasty: An Analysis of the American Joint Replacement Registry (2026)
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Postoperative complications following total shoulder arthroplasty in multiple myeloma patients with prior bone marrow transplantation (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Postoperative Clopidogrel Thromboprophylaxis in TJA (2025)
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2025 ICM: Debridement, Antibiotics, and Implant Retention (2025)
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Total Hip Arthroplasty: A Surgical Revolution. (2025)PubMed OpenAlex
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Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition (2025)
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Interprosthetic Femur Fractures: A Multicenter Retrospective Study (2025)
Grants & Funding
As listed on this researcher's institutional profile.
- AAHKS Fellowship Education and Innovation Program Grant 2024 American Association of Hip and Knee Surgeons Principal Investigator
- Phase 2 Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Chronic Prosthetic Joint Infection of the Knee or Hip Without Exchange Arthroplasty (IRB 298577) Trellis Bioscience Principal Investigator
Collaboration Network
Top Collaborators
- The Effect of the COVID-19 Pandemic on Electively Scheduled Hip and Knee Arthroplasty Patients in the United States
- Choices, Compromises, and Controversies in Total Knee and Total Hip Arthroplasty Modifiable Risk Factors: What You Need to Know
- Flexion Instability After Total Knee Arthroplasty
- Inpatient versus Outpatient Total Knee Arthroplasty
- Rapid Recovery After Total Joint Arthroplasty Using General Anesthesia
Showing 5 of 81 shared publications
- The Effect of the COVID-19 Pandemic on Electively Scheduled Hip and Knee Arthroplasty Patients in the United States
- Choices, Compromises, and Controversies in Total Knee and Total Hip Arthroplasty Modifiable Risk Factors: What You Need to Know
- Flexion Instability After Total Knee Arthroplasty
- Inpatient versus Outpatient Total Knee Arthroplasty
- Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation
Showing 5 of 61 shared publications
- Piezo1 opposes age‐associated cortical bone loss
- The Medial Pivot Design in Total Knee Arthroplasty
- Extensor Mechanism Disruption Remains a Challenging Problem
- Sepsis and Total Joint Arthroplasty
- Suppressive Antibiotic Therapy After Debridement, Antibiotics, and Implant Retention is Well-Tolerated Without Inducing Resistance: A Multicenter Study
Showing 5 of 39 shared publications
- The Effect of the COVID-19 Pandemic on Electively Scheduled Hip and Knee Arthroplasty Patients in the United States
- Choices, Compromises, and Controversies in Total Knee and Total Hip Arthroplasty Modifiable Risk Factors: What You Need to Know
- Flexion Instability After Total Knee Arthroplasty
- Inpatient versus Outpatient Total Knee Arthroplasty
- Rapid Recovery After Total Joint Arthroplasty Using General Anesthesia
Showing 5 of 18 shared publications
- Social Needs of Patients Undergoing Total Joint Arthroplasty
- Streamlining Hospital Treatment of Prosthetic Joint Infection
- Narcotic Refills and Patient Satisfaction With Pain Control After Total Joint Arthroplasty
- The Alpha-Defensin Prosthetic Joint Infection Test Has Poor Validity for Native Knee Joint Infection
- Does Patient Health Literacy Affect Patient Reported Outcome Measure Completion Method in Orthopaedic Patients?
Showing 5 of 18 shared publications
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Senolytics deplete senescent osteocytes and improve bone health in metastatic breast cancer
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 9 shared publications
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Senolytics deplete senescent osteocytes and improve bone health in metastatic breast cancer
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 9 shared publications
- Current status of virtual reality simulation education for orthopedic residents: the need for a change in focus
- Prevalence of Chronic Opioid Use in the Elderly After Hip Fracture Surgery
- Demographics, Treatment, and Cost of Periprosthetic Femur Fractures: Fixation Versus Revision
- Use of the Locking Attachment Plate for Internal Fixation of Periprosthetic Femur Fractures
- The Hip and Femur Fracture Bundle: Preliminary Findings From a Tertiary Hospital
Showing 5 of 8 shared publications
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Senolytics deplete senescent osteocytes and improve bone health in metastatic breast cancer
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 8 shared publications
- Flexion Instability After Total Knee Arthroplasty
- The Influence of Knee Osteoarthritis on Spinopelvic Alignment and Global Sagittal Balance
- Changes in Mediolateral Postural Control Mechanisms During Gait After Total Knee Arthroplasty
- Management of Periprosthetic Joint Infection and Extensor Mechanism Disruption With Modular Knee Fusion: Clinical and Biomechanical Outcomes
- Inter-Rater Reliability of Clinical Testing for Laxity After Knee Arthroplasty
Showing 5 of 6 shared publications
- Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation
- Piezo1 opposes age‐associated cortical bone loss
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
Showing 5 of 6 shared publications
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 6 shared publications
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 6 shared publications
- Skilled Nursing Facility Star Rating, Patient Outcomes, and Readmission Risk After Total Joint Arthroplasty
- Acetabular wedge augments for uncontained tibial plateau defects in revision total knee arthroplasty
- Clinical Practice Guidelines in Action: Differences in Femoral Neck Fracture Management by Trauma and Arthroplasty Training
- Revision Total Hip Arthroplasty in the Setting of a Well-Fixed Cup: Early Report on the Cup-in-Cup Technique
- Revision arthroplasty for periprosthetic joint infections: When to consider one-stage versus two-stage protocols?
- Electronic Medical Record Audit Time Logs as a Measure of Preoperative Work Before Total Joint Arthroplasty
- A Review of Periprosthetic Tibial Fractures
- Extensive Preoperative Work Is Required for Revision Hip and Knee Arthroplasty
- Treatment of Hip and Knee Periprosthetic Joint Infection Requires Extensive Administrative Work
- Amino Acid Supplementation May Help Prevent Muscle Wasting After Orthopedic Surgery, but Additional Studies Are Warranted: A Systematic Review of Randomized Clinical Trials
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