Bethany C. Paxton
Researcher
Also affiliated: Winthrop Rockefeller Foundation (2026)
Unknown Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Bethany C. Paxton's research focuses on understanding and targeting mechanisms of multiple myeloma, particularly dormant and therapy-resistant cancer cells. Her work investigates the role of Notch3 signaling as a potential therapeutic target to eradicate these resistant myeloma populations. Paxton has also explored the restoration of bone health in multiple myeloma through sclerostin inhibition, examining its effects on lytic lesions. Her research utilizes various models, including cell lines and xenograft assays, to study disease progression and therapeutic interventions. Paxton collaborates with researchers at the University of Arkansas for Medical Sciences, including Japneet Kaur, Elena Ambrogini, Aric Anloague, and Sharmin Khan, with whom she has co-authored multiple publications.
Metrics
- h-index: 2
- Publications: 9
- Citations: 6
Selected Publications
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Human REV1 interacts with DHX36 to promote replication and tolerance of G-quadruplex DNA (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition (2025)
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Abstract 5099: Notch inhibition as a therapeutic approach to eliminate dormant cancer cells in multiple myeloma (2025)
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Conservation of the insert-2 motif confers Rev1 from different species with an ability to disrupt G-quadruplexes and stimulate translesion DNA synthesis (2023)
Collaboration Network
Top Collaborators
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Abstract 5099: Notch inhibition as a therapeutic approach to eliminate dormant cancer cells in multiple myeloma
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 7 shared publications
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Abstract 5099: Notch inhibition as a therapeutic approach to eliminate dormant cancer cells in multiple myeloma
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 7 shared publications
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Abstract 5099: Notch inhibition as a therapeutic approach to eliminate dormant cancer cells in multiple myeloma
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 7 shared publications
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Abstract 5099: Notch inhibition as a therapeutic approach to eliminate dormant cancer cells in multiple myeloma
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 6 shared publications
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Abstract 5099: Notch inhibition as a therapeutic approach to eliminate dormant cancer cells in multiple myeloma
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
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