Aric Anloague

Researcher

University of Arkansas for Medical Sciences

faculty

4 h-index 51 pubs 50 cited

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Biography and Research Information

OverviewAI-generated summary

Aric Anloague's research focuses on understanding the molecular mechanisms that drive bone destruction in metastatic cancer and multiple myeloma. His work investigates the role of specific signaling pathways and cellular interactions in these processes. Recent publications examine how osteocytes, specialized bone cells, contribute to bone loss in breast cancer metastasis through senescence and trigger destructive processes. Anloague also studies signaling axes in multiple myeloma, such as NOTCH3-CXCL12 and CCL3-HMGB1, which promote chemoresistance and regulate osteocyte RANKL expression, respectively. His research has explored therapeutic strategies, including sclerostin inhibition, for healing lytic lesions and restoring bone health in multiple myeloma. Anloague's scholarly output includes 51 publications and 50 citations, with an h-index of 4. He has established significant collaborations with researchers at the University of Arkansas for Medical Sciences, including Olivia Reyes‐Castro, Hayley M. Sabol, Japneet Kaur, and Elena Ambrogini, with whom he shares multiple publications.

Metrics

  • h-index: 4
  • Publications: 51
  • Citations: 50

Selected Publications

  • Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026) DOI
  • Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026) DOI
  • Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026) DOI
  • Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026) DOI
  • Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition (2025) DOI
  • Abstract 5099: Notch inhibition as a therapeutic approach to eliminate dormant cancer cells in multiple myeloma (2025) DOI
  • A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma (2024) DOI
  • Senolytics deplete senescent osteocytes and improve bone health in metastatic breast cancer (2024) DOI
  • Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis (2024) DOI
  • A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma (2024) DOI
  • Osteocytes: New Kids on the Block for Cancer in Bone Therapy (2023) DOI
  • Abstract 5675: Pathological crosstalk between osteocytes and breast cancer cells in bone metastasis (2022) DOI

Collaborators

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