Match tier Listed
Presence Current · Arkansas
Last published 2021
Sources OpenAlex · ORCID
Refreshed 2026-08-15

L.P.F. Balapiti-Modarage

Researcher

Unknown Researcher

2 h-index 5 pubs 198 cited

  • Enzyme Inhibitors
  • Glycoside Hydrolases
  • Humans
  • Small Molecule Libraries
  • Poly ADP Ribosylation
  • DNA Replication
  • Neoplasms
  • Poly(ADP-ribose) Polymerases
  • Cell Death
  • Cell Line, Tumor
  • Protein Domains
  • SARS-CoV-2
  • Coronavirus Papain-Like Proteases
  • COVID-19 Drug Treatment
  • Amino Acid Sequence

Biography and Research Information

OverviewAI-generated summary

L.P.F. Balapiti-Modarage studies the structural basis of enzyme inhibition, with recent work focusing on SARS-CoV-2 Nsp3 macrodomain targeting. This research leverages insights from human poly(ADP-ribose) glycohydrolase (PARG) structures and inhibitors. Balapiti-Modarage has authored 5 publications with 189 citations and an h-index of 2. Key collaborators include Shobanbabu Bommagani and Darin E. Jones, both from the University of Arkansas for Medical Sciences, with whom Balapiti-Modarage shares one publication each. The researcher's work is situated within the broader fields of molecular biology and pharmacology, contributing to the understanding of enzyme function and potential therapeutic targets.

Metrics

  • h-index: 2
  • Publications: 5
  • Citations: 198

Selected Publications

  • Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors (2021)
    Progress in Biophysics and Molecular Biology 63 citations DOI OpenAlex
  • Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death (2019)
    Nature Communications 134 citations DOI OpenAlex

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Collaboration Network

13 Collaborators 5 Institutions 1 Country

Top Collaborators

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